“nominally significant”

A nominally significant similar relationship was observed for the right amygdala, though this did not survive multiple comparison correction (Figure 4b ; Table 2 ; t = −2.2; p = .03, q = 0.06).

Although the direction and magnitude of association for 8 SNPs (at the UMOD, GCKR , PIP5K1B , PRKAG2 , STC1 , VEGFA , SHROOM3 , and ALMS1/NAT8 loci) were consistent with our previous findings for eGFR and prevalent CKD [16] , [17] , only two SNPs showed nominally significant associations with ESRD ( Table 2 ): rs1260326 in GCKR (OR = 0.93; p-value = 0.03) and rs12917707 in UMOD (OR = 0.92; p-value = 0.04).

Although 2-component systems did not reach the FDR 0.1 threshold in DINE-CD, it was nominally significant at P = .03.

However, among the 116 EpiScores, only CXCL10 showed a nominally significant difference ( p = 0.03 95% CI: 0.001–0.0188; Figure 1 ), but this did not remain significant after FDR adjustment, highlighting the uncertainty of small effect sizes. 3.5.

The treatment effect for 360 mg, every 2 weeks vs placebo was nominally significant (−16.3%; nominal P = .03); however, significance could not be claimed because the hierarchical testing sequence was interrupted.

While a nominally significant association of higher PGS with lower CSF Aβ 42/40 was observed ( n = 169, uncorrected p = 0.03), the only other biomarker to show a significant association was SNAP‐25.

The CLDN3 variant was nominally significantly associated with dyslexia when comparing the discovery and RD cases with either the TD cohort ( P = 0.03) or the general population (i.e. gnomAD data; P = 0.003) (Supplementary Table 17 ).

We also observed higher insulin levels in LoF heterozygotes and homozygotes in the first 30 min of the test (β=0.59, p =2.6×10 –3 ) and a nominally significant trend toward elevated insulin levels throughout (β=0.34, p =0.03).

We also explored the mRNA expression in decidua of genes ±500 kb of INHBB and found a nominally significant correlation between a transcript encoded by the EPB41L5 gene, ∼250 kb centromeric to INHBB , and preeclampsia (p = 0.03).

In the sub-elite, the recessive model was nominally significant ( p = 0.03), but it did not survive FDR (FDR-adjusted p = 0.09).

SNPs that remained nominally significant (p = 0.03) and therefore contributed to explaining additional THP variance after adjusting for rs12917707 were rs115312009, rs147825435, rs76619864, and rs75432530.

Out of 56 SNPs analyzed, one SNP in the ESR1 gene (rs2982712) was nominally significantly associated with PND (OR 0.83, 95% CI 0.71–0.98, p = 0.03) as well as with persistent depression (OR 0.77, 95% CI 0.61–0.98, p = 0.03) in the overdominant model (DD/dd vs.

Nominally significant greater reductions in infarct size (% of LV) were noted in the LDE-MTX group in the modified intention-to-treat analysis (−3.9 ± 6.9 vs −9.4 ± 8.4, p = 0.030; Table 2 and Fig. 1 ) and in the per-protocol analysis (−2.7 ± 4.7 vs −8.5 ± 5.9, p = 0.024; Supplementary Table 3 ).

We also found a nominally significant association between alcohol intake and risk of HCC ( p = 0.03).

In the NHANES sample ( Figure 2 ), only hypertension demonstrated a nominally significant interaction with the joint association of IADL impairment and depression ( p = 0.03); however, this was not replicated in the CHARLS cohort ( Figure 3 ).

One previous study has reported a nominally significant association between a SNP in the TERT region (rs2736122) and endometrial cancer (reported P = 0.03) (Prescott et al. 2010 ), but this SNP was not significant in our larger analysis ( P = 0.85; Supplementary Table 5), whilst a recent multi-cancer study of nearly 2,000 5p15.33 SNPs did not report an association with endometrial cancer (Wang et al. 2014 ).

There was a nominally significant excess of heart failure (HR 1.34, 95% CI:1.03 to 1.75, p=0.03) but no associations with other studied cardiac outcomes.

The interaction between rs738409 and sucrose intake on triglyceride levels was nominally significant among normal-weight individuals ( P = 0.03), while among overweight individuals, a tendency for interaction was observed with ω-6:ω-3 PUFA intake ratio ( P = 0.08).

A further nominally significant difference was observed for case 8 (p=0.031), which did not survive Bonferroni correction.

Also an inverse relationship between milk and milk product SFA and the proportion of EPA was nominally significant after adjustments (for log-transformed: β = −0.069, P = 0.031).

A nominally significant difference was observed for bevacizumab at the 12-month landmark, favoring grade 2 over grade 3 (68.3% vs. 37.2%, p = 0.031); however, this isolated finding was not supported by a significant global log-rank comparison across grades ( p = 0.09) and was not consistently observed at other landmarks.

Among all methods and metabolites, only the weighted median estimate for GCST90277281 indicated a nominally significant association (OR = 0.93, 95% CI: 0.87–0.99, P = .031), suggesting a possible weak inverse effect.

A single nominally significant finding (procedure–LIX, p = 0.031, ε 2 = 0.05) would not remain significant after correcting for multiple comparisons.

There was a nominally significant relationship between TL and preeclampsia (PE) in the IVW model (OR: 0.799; 95% CI: 0.651-0.979; P = 0.031).

In pairwise meta-regression using the first-line 1/2-gen EGFR-TKIs subgroup as the reference, the later-line third-generation subgroup showed a nominally significant difference ( p = 0.0311), whereas the first-line third-generation subgroup did not ( p = 0.1646).