Although the injection route did not affect the percentage of specific hIgG against functional sites and anti-complexing protein antibodies, intradermal injection of BoNT/A showed a trend toward increasing the production of total hIgG against BoNT/A (Fig. 1 ).
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Although not statistically significant, BCR::ABL1 negativity showed a trend toward increased risk of relapse.
3) For Stage III, immunotherapy showed a trend toward superior DFS versus chemotherapy, though statistical significance was not reached (HR = 0.28, 95%CI: 0.04-1.96, P = 0.204), and both outperformed WW (HR = 0.05, 95%CI: 0.004-0.54, P = 0.014 and HR = 0.34, 95%CI: 0.05-2.17, P = 0.113, respectively).
Contrary to prior findings, LDLr −/− /MD-1 −/− mice exhibited progressive weight gain, with no significant difference compared to LDLr −/− /MD-1 +/− mice, although the latter showed a trend toward a plateau (Fig. 1 a, upper).
Results showed a trend for significant association between HbA1c and H 2 S as continuous variables ( Supplementary Table 2 ).
At T 2 , no significant contrasts emerged (all p > .309), although the Placebo group showed a trend towards higher scores than the VR-Intervention group.
There was a trend towards decreased compliance after SCI compared to Sham animals, and only SCI + acute BoNT‐A treated animals showed a trend towards preserved compliance compared to Sham.
9 Lithium augmentation showed a trend towards greater symptom reduction at the end-point.
Screening showed a trend toward lower all-cause mortality (HR 0.42) but did not reach statistical significance (95 % CI: 0.10, 1.82). 4.
Importantly, we observed the “obesity paradox,” wherein obese patients showed a trend toward better OS compared to non-obese patients in the Appalachian cohort.
All background fertilization treatments showed a trend to reduce CI from Pi to Pf, but these reductions were statistically significant (p<0.05) only in the slow-release inorganic fertilizer (Pi: 57.76 ± 6.85 vs.
Using the HOMA-IR index as a measure of insulin resistance, the Ndst1 AKO mice showed a trend towards increased HOMA-IR even on a chow diet ( Fig. 2 D).
In both univariate and multivariate Cox regression analyses, higher social deprivation showed a trend toward increased mortality, with significant associations in univariate models that attenuated after adjustment for age at diagnosis and sex ( Supplementary Table S7 ).
Subgroup analysis showed no effect of probiotics or antibiotics alone although antibiotics showed a trend towards benefit for long-term decolonisation (RR 1.21, 95% CI 0.99-1.48).
Consequently, several variables that showed a trend toward association with stiffness, such as female sex, age under 50, and partial-thickness tears, may have yielded false-negative results.
In contrast, CD274 /PD-L1 mRNA showed a trend to reduced expression in KEAP1 -mutated and a significantly decreased level in NRF2 signature-high cells from CCLE ( Fig. 7 B–C, top).
Diastolic EL/CO also showed a trend toward systolic EL/CO.
Dermatoscopic features All the reference dermatoscopic features showed a trend towards reduction at 6-months post-treatment when compared with baseline ( Figure 2 and Supplementary Table 1 ).
Patients with R0 resection showed a trend toward longer PFS compared with those with R1/R2 resections (23.1 vs 18.2 months).
Discussion The main findings of this study testing the effect of use of PTX in patients with CCC showed a trend toward reducing serum levels of pro-inflammatory cytokines, such as IL-6 and TNF-α, and increasing serum levels of the anti-inflammatory cytokine IL-10.
Although the difference in mortality was not statistically significant, patients treated with TXA showed a trend toward lower death rates, suggesting potential feasibility for trauma care in both civilian and military settings.
35.44 ng/mL, IQR 28.61–46.34 ng/mL; p = 0.002), whereas the exacerbation subgroup showed a trend toward increased levels (Figure 3A ).
3.3 Effects of pepper - peanut intercropping on photosynthetic indexes of pepper According to Figure 2A , the photosynthetic rate of pepper showed a trend of increasing first and then decreasing.
For severe disability, the multivariable model achieved an AUC of 0.854 versus 0.619 for the univariable model; the difference showed a trend but did not reach statistical significance ( P = 0.088).
In node-negative cases (N0), a high PIV also showed a trend toward worse outcomes, although the results were marginally significant.