In contrast, rhein intervention showed a trend of decreasing TG and LDL-C levels and increasing HDL-C levels.
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Compared to control, concentrations of CML and MG-H1 were significantly increased due to diabetes (both 1.5-fold, p < 0.001), with a significant reduction of CML by GLO1 overexpression (1.2-fold, p < 0.001), while MG-H1 levels showed a trend of increase with GLO1 overexpression, although not significant ( p = 0.113; Fig. 4 B, D).
For mitomycin C, data from two non-randomized studies are available, which only showed a trend towards a survival benefit [ 297 ], [ 339 ].
This mirrors findings in great white pelicans ( Pelecanus onocrotalus ), where reversibly deflighted individuals showed a trend towards higher CORTf levels [ 2 ].
Although not statistically significantly different from the WT, in the reaction with COX, Y67F Cyt c showed a trend toward higher activity, suggesting that the presence of the hydroxyl group has a mild inhibitory effect, whereas the Y67E replacement produced a more pronounced significant inhibitory effect.
Furthermore, the testosterone and intracellular cAMP levels in the pcDNA3.1(+)-lncRWDD3 + 200 ng/mL prolactin group were significantly higher than those in the pcDNA3.1(+)-lncRWDD3 group, and the lncRWDD3 interference group showed a trend toward increased testosterone after 200 ng/mL of prolactin was added, which suggests a facilitating effect of PRL on testosterone secretion ( Figure 5 B).
Dogs turned around more frequently when guiding the unfamiliar tester, possibly seeking reassurance, but showed a trend toward fewer stress-related behaviours.
Similarly, when analyzed within each group, this symptom showed a trend toward elevated IL-6 levels in the Self-RPD+ group (32.9 pg/mL ± 51.1 pg/mL vs. 12.9 pg/mL ± 5.1 pg/mL), although this difference was not statistically significant ( p = 0.078).
In the ITT population, the OS data also showed a trend in favor of atezolizumab but it was not statistically significant and remains immature [ 28 ].
As shown in Table 3 , when the ultrasonic power reached 100 W, P 2b+21 and P 22 showed a trend of increasing and then decreasing with the prolongation of the ultrasonic time, with P 2b+21 and P 22 being significantly higher (p < 0.05) and P 23 being significantly lower ( p < 0.05) than that of the untreated control.
A significant association was observed between BM break counts and the number of anti-VEGF injections in the first year, whereas a higher break count also showed a trend to correlate with better visual acuity; this did not reach statistical significance, these observations, however, should be interpretated in the context of our cohort.
Moreover, with the increase in temperature, T-AOC showed a trend of initial increase followed by a decrease.
Regarding antioxidant enzymes, both the single MPs group and most of the combined exposure groups showed a trend of initial induction, followed by the inhibition of CAT and SOD activities ( Figure 2 B and Figure 3 C).
Bowel resection (HR: 1.438, p = 0.124), stoma formation (HR: 1.739, p = 0.080), and diaphragm stripping (HR: 1.430, p = 0.150) showed a trend toward increased hazard but did not reach statistical significance.
In a previous study, patients affected by PC showed a trend through longer operative time and higher blood loss, even if not statistically relevant, as compared with those affected by other periampullary tumors [ 18 ].
The results showed a trend towards greater model accuracy with more loci used to construct the linear regression model in a certain range of less than five loci.
Under high temperature treatment, the chlorophyll index of grape leaves in the Control group showed a trend of first decreasing and then recovering.
E2 pretreatment showed a trend toward reversing these impairments and improving all OCR parameters, although the changes did not reach statistical significance.
Within the adaptive immune system, PTEN low tumors showed a trend toward higher expression of effector CD8+ cells and B lymphocytes, with overexpression of the immunoglobulin gene signature (IGG signature) [ 24 ], Zhao’s prostate immune-related signature [ 25 ], and exhausted T cell signature.
The comparative analysis of geographical origin across study years showed a trend toward urban predominance, though this was not statistically significant (χ 2 = 16.665, p = 0.082).
Interestingly, CD44, a known GBM stem cell marker [ 48 ], showed a trend towards reduced—though not significant—expression in orthotopic xenografts after COX-2 knockout.
NJ in the Cll were found to be statistically significant, they showed a trend toward normalization vs.
The result of nephrotoxicity induction shows that PCM administration increased these parameters in the plasma ( Figure 2 ); however, only creatinine and uric acid were significantly increased, while urea showed a trend toward increased levels.
Furthermore, a study found that regular consumption of matcha improved emotion perception and showed a trend toward better sleep quality in older adults with mild cognitive impairment.
At the same time, CX516 showed a trend toward cognitive decline in the novel object recognition (NOR) test and anxiogenic effects in the elevated plus maze test.