Nimutuzumab as a humanized EGFR mAb with less toxicity showed a trend benefit for ORR and OS in the second-line treatment of advanced ESCC ( Wang et al., 2024 ).
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Among patients with GBM, the p53-negative subgroup in the AFTV group showed a trend toward improved survival (65.6 months mOS) compared to the same subgroup in the control group (35.8 months).
As VSM/Ps differentiated, the expression of PALLD showed a trend of first increasing, then decreasing, and then increasing again, while the overall expression trend of R3HDM1 did not change significantly (Fig. 10 g-h).
With the increase in okara addition, the SHF content in both doughs showed a trend of decreasing and then increasing, while SS content showed a trend of increasing and then decreasing.
Monocyte counts showed a trend toward higher values in COPD patients, though this difference did not reach statistical significance (0.46 ± 0.25 vs. 0.43 ± 0.26 × 10 9 /L, p = 0.059).
However, both independently assessed lean mass indicators showed a trend toward improvement in the HL-BFRT group.
When considering only the top eight fencers per event, the overall sample showed a trend toward RAE, with a higher proportion of athletes born in the second and third quarters.
The simulated Chinese adolescent population showed a trend for higher median exposure than in Chinese adults ( C max +16.8%, C avg +19.9%, C trough +24.7%) due to differences in body weight but with a large overlap of distribution between the two groups.
For composite brain SUVR, higher BMI was significantly associated with lower SUVR B ( p = 0.0046), while SUVR SG showed a trend toward reduced SUVR B , though it did not reach statistical significance ( p = 0.0701).
Maize biomass showed a trend of cumulative increase as fertility advances, with biomass values peaking at the end of the growth period.
Although 2.5% NaCl also showed a trend toward increased tumor formation, it did not reach statistical significance ( Takahashi et al., 1994 ).
Results showed a trend toward larger (more negative) α- ERD in HSNO compared to the other conditions (Fig. 2 b), with a significant difference only between HSNO and SRHY (t = -3.62, p holm = 0.002).
It can also be seen that the four vegetation types consistently showed a trend of increasing, then decreasing, and then increasing with the increase of soil layers, and the HR peaked at 0–60 cm and 120–200 cm, CK at 60–80 cm, and 100–120 cm, and SC at 80–100 cm layers.
glabripes showed a trend toward association with OS, these did not reach statistical significance.
Given that as adults age the number of comorbidities increases, we showed a trend in every age group for increased risk of ICU admissions and mortality with increasing numbers of comorbidities.
They found that, while both approaches improved spine BMD, only the sequential approach showed a trend toward improved FN-BMD.
3 F), an important regulator of microglia proliferation, migration, and phagocytosis [ 32 , 95 ], showed a trend toward increase in AD-water group.
However, unloading showed a trend towards partial mitigation of the induced degeneration with decreased iNOS and TRPV4 expression, an increased water/sGAG ratio, reduced sGAG release, and recovery of the disc height.
Relugolix also showed a trend toward a higher percentage of patients with testosterone recovery 90 days post-treatment cessation and a 54% lowering of the risk of major adverse cardiovascular events compared with leuprolide; and this was all based on the data generated from the HERO trial, which we published in the New England Journal [of Medicine] [ 7 ].
Consistent with this, the melanoblast deficit in embryos showed a trend to a decrease from E11.5 to E15.5, although this was not significant, at least with these cohort sizes.
Neurological symptoms Individuals with loop variants in CSNK2A1 showed a trend toward a higher number of non-seizure neurological symptoms, though the difference was not statistically significant ( p = 0.11, Figure 5A ).
The cell membrane/cytoplasm ratio of Rho was similar to that of ASIC1 in Glu-induced HT22 cells Rho in the total protein showed a trend of initially increasing, then decreasing, and then gradually increasing again ( Figure 2A,B ).
The number of DALYs showed a trend of younger aggregation as the SDI decreased, and the upward trend of ASDRs with age became gentler.
The analysis showed a trend towards an interaction between SMI and treatment on OXY; however, this was not significant (χ 2 =3.331, P =0.068).
In contrast, while SOD levels showed a trend toward reduction, and MDA levels tended to increase, neither change reached statistical significance ( Figure 1D–E ), suggesting that while oxidative stress is apparent, certain oxidative markers like SOD and MDA may be less sensitive to CPF’s effects or may require longer exposure for significant alterations to manifest.