Barely Significant
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“showed a trend”

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In the literature

Notably, metformin treatment showed a trend toward increased expression of cell cycle regulators, such as p21 and Cdkn1b (not statistically significant), while significantly reducing the expression of the angiogenesis-related gene Mmp9 and showing decreasing trends in Mmp2 and the inflammation-associated gene Nos2 ( Fig. 4D and E ).
did not reach statistical significanceP = 0.0861.7× alphaplainly factual
In addition, the difference in change from baseline between the groups (Extended Data Table 1a ) showed a trend toward a reduction in arterial inflammation in the low-dose IL-2 group compared to placebo, but did not reach statistical significance (−0.103, 95% CI −0.22 to 0.02, P = 0.086).