“showed a trend”

PMR did not reduce lipid accumulation in PLC/PRF/5 and showed a trend toward increased lipid signal under FA, whereas metformin alone (and within PMR) reduced lipid signal in HepG2.

Additionally, in line with the observations in MCF7 cells, T47D cells showed a trend toward an overall increase in H3K27ac following E2 and FULV treatment at different time points, although these changes did not reach statistical significance (Supplemental Fig.

Among individuals aged ≥ 80 years, operated patients showed a trend toward lower lethality, although the difference was not significant.

Compared with the SIS3 and NPs-SIS3 groups, NPs-SIS3-Ab also showed a trend toward lower expression of these genes (Sup Fig. 4A).

Prematurity (gestational age < 37 weeks) showed a trend toward increased risk but did not reach statistical significance after adjustment (OR = 1.18, 95% CI 0.98–1.42, P = 0.08).

After the intervention (S2), the gut microbiota composition in the placebo group showed a trend toward recovery but was not fully restored to the baseline (S0) state.

For the Heteronormative beliefs: normative behavior scale, straight students showed a trend towards a small increase in heteronormative beliefs, while LGBTQ students showed a trend towards a decrease in heteronormative beliefs, however, the mean changes in this scale were not significantly different from zero for any of these groups (LGBTQIA-Maybe: W = −3.00; p = 0.500; LGBTQIA-No: W = 417.00; p = 0.146; LGBTQIA-Yes: W = −46.00; p = 0.163).

By 14 dpi, however, the m54.5p-null mutant was significantly attenuated (p = 0.0171) by ≈3-fold in lungs, and showed a trend towards attenuation in salivary glands ( Fig 6 ).

This was driven by C > A transversions which showed a trend toward being more frequent in the long-generation group (posterior probability = 0.858) ( Figure 3B ).

Our cohort showed a trend toward worse survival with higher SII, consistent with prior studies ( 12 ).

While the Abx group also showed a trend towards increased TC and LDL-C, the changes in TG and HDL-C did not reach statistical significance ( Figure 2D ).

In this subset, triple therapy showed a trend toward longer PFS than dual therapy, though the difference did not reach statistical significance (HR 0.70, 95% CI 0.39–1.26, P = 0.235).

Non-inoculated plants showed a trend toward increasing glucose and fructose levels with rising salinity.

In the multivariate Cox regression analysis, the five-gene signature (riskScore) showed a trend toward worse prognosis (HR = 1.374, 95% CI: 0.916-2.061), though it did not reach statistical significance (P = 0.125), potentially due to limited sample size ( Supplementary Figure S3B ).

The high-risk group showed a trend toward a higher predicted non-response rate based on the TIDE algorithm, suggesting a potentially poorer response to immunotherapy that warrants further investigation ( Figure 2I ).

Compared to the control group, 2 μM 3-OH-B[a]A significantly increased the p-AKT/AKT ratio ( p < 0.05), while 0.4 μM 3-OH-B[a]A showed a trend toward elevation but did not reach statistical significance.

At the family level, early disease mice exhibited the largest deviations from naïve controls, with decreased Lachnospiraceae and increased Prevotellaceae , Rikenellaceae , and Muribaculaceae , while during pre-disease, mice already showed a trend toward lower Lachnospiraceae and higher Lactobacillaceae ( Figure 6B ).

61.8% (21/34), p = 0.001), and LE showed a trend of shorter median occlusion time (0.0 (0.0–11.25) min vs. 0.0 (0.0–30.0) min), though the difference was not statistically significant ( p = 0.105).

χ 2 test analysis showed no statistically significant differences in the distribution of sex, educational level, or marital status between the two groups (p > 0.05), although descriptive data showed a trend toward an increasing proportion of unmarried individuals and higher education levels with increasing nutritional risk scores.

A post hoc comparison of baseline characteristics between dupilumab-treated patients with or without optimal response in pooled PRIME/PRIME2 showed a trend for more severe disease at baseline in dupilumab-treated patients without optimal response versus optimal responders, including higher proportions of patients with an IGA PN-S score of 4 (35.4% of patients without optimal response vs 27.8% of optimal responders) and a PGIS “severe” score (75.8% vs 68.5%), as well as fewer healed lesions from PAS (≥ 50% healed lesions from PAS in 7.1% vs 13.0% of patients) and higher use of antidepressants (11.1% vs 9.3%) (Supplementary Table 1 of the ESM).

In univariable analyses, age, PS, and the composite risk classification showed a trend or significant association with NRM ( Table 2 ).

Overall, the groups that underwent additional cartilage procedures showed a trend toward lower MCID achievement rates at 6 months; however, by 12 and 24 months, their MCID achievement rates became comparable to those of the isolated HTO group ( Figure 5 ).

This finding is consistent with the study by Arun-Kumar and Naresh-Babu, who reported that local infiltration of TXA showed a trend toward reduced intraoperative blood loss but with comparable effectiveness to intravenous TXA in spine surgeries [ 8 ].

After adjusting for age and other confounders, BP use was independently associated with improved OS, whereas RFS showed a trend toward benefit, particularly among patients aged ≥60 years.

However, survival analysis showed a trend toward delayed tumor recurrence in mice receiving the 5-FU + KRCT6j combination compared with the control and 5-FU monotherapy groups (Fig. 5 F), although this difference did not reach statistical significance, suggesting a potential role for TYRO3 inhibition in delaying tumor recurrence.