“showed a trend”

11 Lastly, when assessing for multiple factors in female patients in New York City, only intimate partner violence showed a trend to increased bodily trauma. 6 As illustrated above, sexual assault and resultant physical trauma are multifactorial public health concerns requiring further investigation.

A recent double-blind randomised controlled trial in young adults reported that 1 month of high-dose vitamin B 6 supplementation (100 mg/day) reduced self-reported anxiety and showed a trend towards reduced depressive symptoms compared with placebo, consistent with a role of vitamin B 6 in enhancing GABAergic inhibition ( 16 ) .

The VCNs showed a trend consistent with the fluorescence levels, with SRV2 RV transduced T and NK cells exhibiting slightly higher VCN values (Fig. 2e, j ).

At the gene expression level, qPCR analysis revealed that miR-205a mimic treatment significantly reduced Wnt4a mRNA levels, showed a trend toward downregulation of β-catenin , and upregulated GSK-3β , though the latter change did not reach statistical significance.

In Got1 cKO retinas, both heterozygous and homozygous cytosolic Lb NOX expression in rod PRs showed a trend towards restoring the fractional change in retinal OCR following FCCP treatment to WT levels, with a stronger rescue observed in the homozygous group ( Supp.

4.4 All-cause mortality Mortality data was pooled from all four studies and sotatercept showed a trend toward reduced mortality (OR 0.63; 95 % CI 0.33–1.20).

In the first-line CheckMate 649 trial, EBVaGC patients showed a trend toward improved survival with nivolumab plus chemotherapy (HR 0.61, 95% CI 0.26–1.45) or nivolumab plus ipilimumab (HR 0.76, 95% CI 0.22–2.64) compared to chemotherapy alone, although these results were not statistically significant due to the small subgroup size 26 .

Nevertheless, the cTnI levels returned to normal in only a few children, whereas the vast majority showed a trend toward repeated or continuous elevation of cTnI levels.

Similarly, while preoperative ctDNA showed a trend toward increased relapse risk, consistent with prior EC studies [ 47 ], this did not reach statistical significance.

39 In this study, NT-RFA showed a trend toward improved RFS (HR 0.81, 95% CI 0.57 to 1.15).

Live intranasal influenza vaccine showed a trend towards benefit in laboratory-confirmed influenza (RR 0.49, 95% CI 0.21 to 1.17), and an inconclusive effect in systemic adverse events ( general malaise: RR 3.09, 95% CI 0.18 to 53.20; fever: RR 1.71; 95% CI 0.09 to 33.24. 58 , 74 Administration of high-dose influenza vaccine in the elderly significantly reduced laboratory-confirmed influenza (RR 0.76, 95% CI 0.64 to 0.90), all-cause hospitalization (RR 0.93, 95% CI 0.90 to 0.96), and serious adverse events (RR 0.92, 95% CI 0.87 to 0.98) compared to standard-dose influenza vaccine.

Counseling on a healthy diet showed a trend towards benefit on composite cardiovascular outcomes that included myocardial infarction (MI), coronary heart disease death, cardiovascular death, need for myocardial revascularization, and stroke, compared to no NPI (RR 0.92, 95% CI 0.85, 1.00). 18 – 20 However, counseling on HD had no benefit on all-cause mortality (RR 0.98, 95% CI 0.90 to 1.05) and cardiovascular mortality (RR 0.98, CI 0.79 to 1.22).

60 Among children, one observational study with a long-term follow-up of 16 years reported that a brief 2 to 3-minute intervention, which included asking about smoking status and counseling, administered during routine dental visits, showed a trend towards benefit in reducing the likelihood of smoking in adulthood (OR 0.78, 95% CI 0.56 to 1.09). 61 A systematic review of 67 studies compared self-reported smoking with direct measurement of cotinine levels from biological fluids. 62 Pooling of results was not done because of substantial heterogeneity.

For VE-LQM, both sorghum and rice foreground abundances generally showed a trend of first increasing and then decreasing.

The NC-miRNA-mEVs, which were loaded with nonsense miRNA sequences, showed a trend of reducing type 2 inflammatory cytokine levels, but there was no statistically significant difference compared with the inflammation stimulation group.

In parallel, the composition and diversity of the intestinal microbiota showed a trend toward restoration.

The use of liquid plasma and cryoprecipitate showed a trend toward lower utilization in LMICs, although these differences did not reach statistical significance after correction.

The methylene proton of the n -pentyl chain in 1 H NMR showed a trend similar to CBN 1 : 2.36 ppm (CBD 2 ), 2.57 ppm ( 2a ), and 2.91 ppm ( 2b ).

3 Although anxiety scores showed a trend toward reduction, variability was observed and changes should be interpreted with caution.

Daily duration did not modify this association, but total cumulative time showed a trend toward a negative association with burden.

The low-calcium cluster (Cluster 2) also showed a trend toward reduced filter lifespan.

The occurrence of high-grade lesions (CIN2 and above, including CIN2, CIN3, and cervical cancer) showed a trend across age groups—highest in the ≥65-year group, followed by the 55–64, 25–34, 35–44, ≤24, and 45–54-year groups.

4 However, although our findings showed a trend toward lower bacterial diversity in the OAB group, they did not support this hypothesis, consistent with other studies that found no significant changes in diversity. 12 , 13 Previous studies comparing urine and vaginal bacteria in individuals with and without UUI found no differences in diversity but noted differences in Lactobacillus species between the two groups. 13 , 21 This finding suggests that the key distinction might not be in the overall diversity of the urinary microbiome but rather in the specific types of bacteria present.

At the 6-month time point, only one cluster showed a trend towards a significant difference between the two groups ( Fig. 6B ).

Variables including numeric radiosurgery dose (HR = 1.35; 95% CI 0.99-1.87; p = 0.061) and loss of coordination at clinical presentation (HR = 2.74; 95% CI 0.94-8.02; p = 0.065) showed a trend towards association but did not reach statistical significance.