On the other hand, studies on breast and ovarian cancer demonstrated that the patients with the PIK3CA mutation showed a trend towards a favorable prognosis [ 32 – 34 ].
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The monophasic group showed a trend toward obesity when compared to the biphasic group, with higher BMI and waist circumference (in both males and females), though these differences did not achieve statistical significance.
When compared to 10 healthy donors, with an equal number of men and women, male CLL patients had lower steroid levels with significant differences noted for DHEA-S, DHEA, and ADT; female CLL cases showed a trend towards lower DHEA-S and DHEA levels (Fig. 3 a, left panel).
Modifying the model from previous studies In previous studies, we showed a trend towards an effect of sumatriptan on cilostazol induced headache in both healthy volunteers and in MO patients [ 2 , 3 ].
6c ); also NP-40 insoluble species of TDP-35 showed a trend of reduction in presence of BAG3, but differences are not significative.
The HDL-C concentration showed a trend to being lower than the control group.
However, a meta-analysis of eight observational studies with different types of chelators involving 1562 participants (median participants per study: 153; range: 78–534) showed a trend toward longer OS in patients who took chelators particularly those with LR-MDS.
Immunoblot analysis of 4HNE products identified two major bands corresponding to molecular weights of 70 and 100 kDa, which showed a trend toward an increase in cerebral hemispheres, hippocampus, thalamus, and cerebellum; however, such changes were not significant ( Fig. 9 ).
Effluent glucose showed a trend to being higher in DCD livers than DBD livers (DBD median 9.7, IQR 5.5‐11.2; median DCD 12.2, IQR 6.8‐22.1 mmol/L). 3.6 Glucose challenge to interrogate a non‐rising perfusate glucose Two of the four livers which did not generate a perfusate glucose above 10 mmol/L were interrogated with additional glucose (Figure 6 ).
Additionally, patients with nonprogression of PDR showed a trend towards an overall decrease in BA across all time‐points, whereas patients with progression of PDR were somewhat unchanged.
Sterole levels in plasma and liver lysates showed a trend toward lower levels in Wls‐HECKO that did not reach statistical significance ( http://onlinelibrary.wiley.com/doi/10.1002/hep.29613/suppinfo ).
In univariable analyses, adjuvant radiotherapy showed a trend towards more complications (OR 7·23, 0·75 to 69·95) and removal of the implant (OR 5·12, 0·76 to 34·44), without reaching statistical significance.
We observed that slow-growing tumors induced by a low dose of MCA (5 μg) expressed high levels of cell surface NKG2D ligand and showed a trend to develop earlier in NKG2D-sufficient than NKG2D-deficient mice ( 35 ).
3.4 Exposure‐response relationships for serum sodium There was no apparent trend in serum sodium concentrations over time in the placebo group, while some patients in each of the ESL groups (particularly the highest dose group) showed a trend for decreasing serum sodium concentrations over time (data not shown); these patients were considered outliers.
Both enzymes showed a trend of increasing, reaching a peak at 24 h, followed by a gradual decrease.
The SOFM showed a trend in the results and indicated the resemblance in CYP’s expression under the influence of CsA.
Furthermore, DCW also showed a trend of increasing first and then decreasing.
In addition, the lesional skin of DMF-treated animals showed a trend toward lower relative numbers of CD11b + Ly6C Lo monocyte-derived cells at day 11 after the first antibody transfer (Figures 1 C,D).
Conversely, the mean spike rate within a burst and its mean duration showed a trend to decrease ( Figures 2E2 , F2 ; spike rate, SE: 6.33 ± 1.49 Hz; 1w: 5.56 ± 0.13 Hz; 2w: 4.71 ± 0.11 Hz; 3w: 4.24 ± 0.06 Hz; burst length, SE: 14.0 ± 1.66 s; 1w: 7.4 ± 0.2 s; 2w: 6.6 ± 0.1 s; 3w: 6.4 ± 0.1 s; refer to figure for P values).
The accumulation of PAs showed a trend that increased initially and then decreased gradually back to baseline.
Results: Genotype and echocardiography were recorded during the inclusion period in 100 patients, 79 of whom were classified as having severe genotypes. Although the severe group were younger they had a lower fractional shortening (33.66 ± 6.6 vs 36.9 ± 6.3, P < .05), left atrial area (14.9 ± 3.6 versus 18.0 ± 4.2 cm 2 ; P < .01) and volume (39.9 ± 18.7 versus 51.0 ± 18.7 mL; P < .05) and showed a trend to lower left ventricular ejection fraction.
Results showed a trend toward statistical significance in reduction of verbal comprehension (113.3 vs. 112.0) and a statistically significant reduction of perceptual organization (110.4 vs. 101.7), freedom from distractibility (110.1 vs. 98.5), and processing speed (111.6 vs. 104.2) ( 10 ).
This discrimination was not feasible with Th1, Th2, or Th17 cytokines, although IFN-γ showed a trend to discriminate between AIR and HS.
As shown in Figures 6d and 6e , lysosomes from nfe2l2 -KO mice showed a trend toward reduced RNASE uptake in comparison with Nfe2l2 -WT littermates, although it did not reach statistical significance.
Spontaneous food intake in absolute amounts measured over 24 hr showed a trend of increase in CNO-treated Arc→hM3Dq Cartpt cre/cre mice where CART is absent when compared to the same mice injected with saline ( Figure 4A ); this increase reached statistical significance when expressed as a percentage of BW ( Figure 4B ).