“showed a trend”

However, although the majority of expressed precursor tRNAs showed a trend toward a decrease ( Fig. 3 b and Table S2 ), at the individual gene level only four tRNA genes demonstrated a statistically significant decrease (FDR <0.05), due to the variability in the genotypes of the three mutants.

Moreover, these bivalent cis-elements showed a trend toward reduction of H3K4me3 peak intensity in all patients, suggesting a correlation between a prolonged exit from the cell cycle as a consequence of Ibrutinib treatment and demethylation of both H3K27me3 and H3K4me3 at silenced chromatin.

Overall, the results showed a trend towards a reduced incidence and related risk of stroke and ICH associated with rivaroxaban use compared with phenprocoumon.

However, even lower dose steroids (≥1 to 2 mg/kg/day) showed a trend toward significance in the multivariable models, and this was included in the weighted score.

DFS, PFS, and EFS showed a trend of better outcomes for those perfused with cisplatin, but likely due to the small number of patients in the study and shorter follow-up period of the cisplatin cohort, these differences were not significant.

In addition, participants with diabetes and normal albumin level showed a trend of lower FR+CTC levels compared to those without diabetes and albumin level <35 g/L, but the differences were not statistically significant ( P =0.0631 and 0.0645, respectively).

Nutritional enrichment affected gephyrin ( F 2,16 = 4.9, p < 0.3) and KCC2 levels ( F 2,16 = 7.0, p < 0.01) and showed a trend of effect on GAD65/67 levels in Mthfr +/- female mice.

A future work will be focusing on evaluating other candidate cytokines (which in the present study showed a trend of change but with no statistical significance) such as IL-6, GM-CSF, CCL-5, and membrane protein DNAM-1 in HPV infection; (3) in the mixing of specimens for flow cytometry analysis, according to Hubert's study [ 21 ], the number of NK cells in cervical biopsies was too low to score, and they could only be counted in the stroma.

The first set consisted of two subgroups: catheters which showed a trend of increasing CMD-glycerol (climbers) and catheters which did not (decliners) (Fig. 2 ).

Secondary End Point The NRS analysis showed a trend of difference between groups.

In studies on a small number of MCI patients, treatment with Posiphen for 10 days reduced in CSF the secreted amino terminal fragments of APP (i.e., sAPPα and sAPPβ), total tau, p-tau, and showed a trend toward reduced Aβ42 ( Maccecchini et al., 2012 ).

In fact, the phase Ib/IIa study showed a trend toward dose dependence for reductions in iPTH and corrected calcium at evocalcet doses up to 12 mg in hemodialysis patients, although there was a limitation that the number of patients in the 8 and 12 mg groups was small [ 3 ].

In both buffaloes and cows, mycorrhizal milk samples showed a trend of a higher n ω-6/ω-3 ratio than nonmycorrhizal.

Interestingly, the residual strength of the GRAC showed a trend of first increasing and then decreasing with the increase of exposure time.

The roll angle error during the whole flight test is about 7°, and the error showed a trend of divergence.

A well-established mature endothelium marker so-called PECAM1 also showed a trend of upregulation.

Although exploratory analysis showed a trend towards lower leptin levels after an incomplete course of steroids, this did not reach statistical significance, and it is unclear if the association could be related to an acute suppressive effect of the initial steroid dose on placental leptin transfer and/or a stimulatory effect of >24 hour steroid exposure on adipocyte leptin production.

4 f), although the more posterior cortical regions also showed a trend towards a decrease (data not shown).

Further analyses utilizing historical controls also showed a trend similar to that for the internal controls.

Peripheral but not splenic CD4 T cells additionally showed a trend toward elevated levels of phosphorylated IRF3 (Ser396) ( Fig. 4j and m ).

However, 18 F-FDG uptake in nuchal SAT showed a trend towards lower TBRs during TSH suppression, in contrast to the findings in the vasculature.

Patients with abnormal QRS axis showed a trend of worse overall survival rates; however, the p value was not significant (p = 0.055, Fig. 1B ).

However, VEGF and the first receptor (VEGFR1) showed a trend towards a down‐regulation in gastrocnemius muscles of Irf3 −/− and Irf7 −/− mice compared to C57BL/6 mice (Figure 5 F,G).

High expression of miR-20b showed a trend towards earlier time to BCR, although this was not statistically significant (miR-20b, p = 0.18, logrank test, Fig. 4 ).

CD8 infiltration by IHC only showed a trend towards improved OS, but CD8A transcript levels were significantly associated with better OS (HR 0.72 (95%CI 0.55–0.95; p = 0.016, Fig 3B ).