Arginine supplementation showed a trend towards a decrease in VOC pain and a significant decrease in opioid use in children with SCD 113 .
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35 , 36 Immunoblots of hepatic lysates showed a trend for increased PERK phosphorylation in Ephx2 fl/fl mice upon ethanol feeding and attenuation in Alb- Cre; Ephx2 fl/fl mice ( Figure 6 B ).
Furthermore, no significant changes in bile flow and biliary excretion of BAs were observed between aged WT and Slc10a1 -/- mice, although Slc10a1 -/- mice showed a trend toward slightly increased bile flow ( Figure 4 D and E ).
The only example where increased sucrose showed a trend toward impacting oral colonization was for A12, where recoveries from oral swabs were consistently at least 5-fold higher in the high-sucrose diet than the average diet at day 10 and day 20.
Interestingly, cytarabine treated cells with no addition of FL showed a trend of increased pERK1/2 expression similar to adding 30 ng/mL FL to control cells.
15 , 16 However, a meta‐analysis of randomized trials in cardiac surgery showed a trend towards benefit of a liberal transfusion strategy, whereas in observational studies, transfusion (vs no transfusion) was associated with higher mortality. 31 In critical care patients, a randomized trial found that a liberal transfusion strategy (transfusion started when hemoglobin was <9 g/dL)
Univariate testing of independent variables like LVEF <50%, and BMI > 25 kg/m 2 showed a trend toward a positive association.
CpG ODN priming prolonged the course of pneumococcal meningitis, and CpG ODN-treated mice showed a trend towards lower mortality.
Interestingly, the AUCs for MetS generally increased along with age stratification in men, while in women generally showed a trend of rising first and then decreasing.
Among parameters assessing the nutritional status, low B12 intake (OR = 2) showed a significant association with Vitamin B12 deficiency, whereas low calorie intake (OR = 1.89) and a lower calcium intake (OR = 1.7) showed a trend toward positive association though not statistically significant.
Pretreatment with 1 μ M DEX or GIE showed a trend to reduce the phosphorylation of NF- κ B p65 proteins, but no significant difference compared to LPS plus IFN- γ -induced cells (IN) ( p > 0.05).
Overall, 16,835 of 17,698 genes showed a trend of decreasing modification level of 5hmC in FL than DLBCL, and 50% of the total 5hmC differential modification between DLBCL and FL was driven by a small proportion of genes (~10%) (Fig. 1d ).
The significant difference in IGLL5 did not reoccur in the qRT-PCR independent cohort, but showed a trend consistent with RNA-seq observations, with approximately 10% of women with PMD showing strikingly higher (>12-fold) IGLL5 compared to controls after E2-withdrawal (Figure S6C, D).
Vehicle-treated Rac2 −/− BMDM showed a trend toward lower cholesterol ester accumulation relative to vehicle-treated WT BMDM, although this difference was not significant (Fig. 3 e).
Nevertheless, the results from qPCR showed a trend for an early upregulation of Dlx1, though not statistically significant, and a significant upregulation of Dlx6 and 5, as well as significantly elevated and sustained expression of Gad1 through 14 dpt.
Peptide VP treatment showed a trend for increasing Treg cells, decreasing Th17 cells, increasing the ratio of Treg/Th17 in the spleens and PLN, but there was no significant difference.
3 d) showed that while SP1 protein levels were significantly decreased in RM villus trophoblasts compared with control samples (The percentage of SP1 positive stain cell is 12.2 ± 0.8 % and 18.3 ± 1.1 %, respectively, P <0.05), the CXCR5 and BMP8A protein expression levels showed a trend of reduction in the RM placental trophoblasts, but the difference did not reach a statistical significance (The percentage of CXCR5 positive cells is 7.3 ± 0.4 % and 8.5 ± 0.4 %, respectively, P > 0.05; The percentage of BMP8A positive cells is 8.0 ± 0.5 % and 8.6 ± 0.3, respectively, P > 0.05), suggesting that CXCR5 may be less likely related to RM pathogenesis than SP1does.
Postoperative prothrombin time, prothrombin activity, international normalized ratio, and total bilirubin showed a trend toward improvement.
Non-irradiated SF3B1- mutated CLL cells showed a trend towards a higher expression of ACSM3 with large variation between patients, which could not be linked with VAF of the mutation.
The learning group effect showed a trend towards significance only when considering the sequence errors.
Flow cytometric analysis on day 7 demonstrated that V-iTregs as well as C-iTregs showed a trend toward suppressing allograft infiltration of CD45 + leukocytes, CD4 + T cells, CD8 + T cells, and F4/80 + macrophages compared with that of the control group without iTreg transfer, albeit without statistical significance ( Fig 4C ).
Patients with radiological progression on MRI (PRECISE 4-5) showed a trend to an increase in PSA density.
For AIs, the HR showed a trend towards longer PFS for patients with non-VM versus those with VM, but the 95% CI crossed 1.
In a previous study, haplotype construction, including R287Q and K55R, also showed a trend for a deleterious impact of the 3′-UTR SNP on the outcome of deceased-donor renal transplantation in Caucasians 15 .
Of these, six miRNAs were significantly upregulated after UNC1999 treatment (i.e., miR-130a-3p, miR-134-5p, miR-192-5p, miR-4429, miR-223-3p and miR-320c) and four miRNAs showed a trend towards upregulation (i.e., miR-494-3p, miR-23a-3p, miR-21-5p and miR-27a-3p) (Supplementary Fig. 6h–v ).