“showed a trend”

In addition, cluster B patients showed a trend towards superior spike (S1)-, nucleocapsid (N)- and membrane (M)-specific T cell responses as enumerated by IFN-γ or IL-2 spots forming units (SFU)/10 6 PBMCs ( Figure 5 H), and cluster B accumulated significantly more patients with ≥15 S1-specific IFN-γ SFU/10 6 PBMC than cluster A ( Figure 5 I), suggesting that cluster B patients had a more robust SARS-CoV-2-specific cellular immune response as early as a week after symptom onset.

In SMA type-3 patients, the index scores for verbal comprehension, perceptual reasoning, and working memory did not differ from the normal population but showed a trend of IQ scores towards lower points.

The expression level of MiSVP2 in leaves and buds showed a trend of first decreasing and then increasing, and the lowest expression levels occurred during floral differentiation.

The level of serum E2, vice versa, showed a trend towards the increase in all treated groups, especially in ETU-H sample ( Figure 1 A) vs.

Similarly, our study also showed a trend of increasing TG and decreasing HDL-C as the incidence of IHD increased.

Following bovine insulin treatment, the levels of glucose in the haemolymph showed a trend of first decreasing and then increasing, which was followed by a decrease in comparison to the PBS-buffer-treated group ( Figure 2 H); this trend was likely caused by subsequent changes in glucose levels in pupae treated with bovine insulin.

While in otherwise wild-type animals, PHB depletion showed a trend to increase the content of lactate, in daf-2 mutants, PHB depletion showed a trend to decrease lactate content.

Blood biochemistry after 6 weeks showed a trend toward the reduction of AST with the highest sEV dose, which became significant after 12 weeks in comparison with vehicle and lower dose sEV.

PD03-treated cells also showed a trend towards increased CGB expression ( Fig.

tb + SIV)) showed a trend to be higher than that measured in Group 3 (M. tb only) ( Figure 2 I). 3.2.

Although not significant, the steroid group showed a trend toward reduced 28-d mortality[ 89 ].

The glycolytic capacity ECAR of CD8 + T cells of chronic HIV-infected cART–naïve was not higher than uninfected, and chronic cART treatment showed a trend to decrease in glycolytic capacity ECAR ( Fig 2G and H and Table S1).

3.4 Gel strength and WHC analysis Table 1 shows the strength of the emulsion gel, and the gel strength after HIU treatment at different powers showed a trend of first increasing and then decreasing with increasing ultrasound power.

Several data were acquired in both experiments: the lung-weight and wet-to-dry ratio showed a trend toward a greater increase in pigs with higher mechanical power, without achieving statistical significance in the single experiments.

Response of Wheat Stem Dry Weight per Length to Light Quality in Population Dry weight per length in the wheat stem of both varieties showed a trend of increasing and then decreasing from anthesis to dough stage.

In the DM group, most IVIM parameters showed a trend of rising first and then falling over time.

Signs of life ( p = 0.03) and witnessed cardiac arrest ( p = 0.04) showed a trend towards improved neurological outcomes, however both failed to reach the Bonferroni-corrected p-value threshold.

Further analysis of the individual lesions showed a trend towards a higher level of tumor heterogeneity, as measured by K app , in the pseudoprogressive lesions throughout the first 12 weeks of treatment (baseline: 0.84; 3 weeks: 0.64; 12 weeks: 0.76) compared with the responding lesions (baseline: 0.59; 3 weeks: 0.54; 12 weeks: 0.56); although this did not reach statistical significance, it may reflect underlying immune cell infiltration or cell death over the course of treatment.

In our current study we found that microstate D showed a trend toward a decrease in CHMP2B -FTD as compared to controls.

The IgG responses to the seven vaccine serotypes showed a trend consistent with the OPA responses (Supplementary Figure 2).

27 Despite the proven benefits of statins, the data from the SPARCL (Stroke Prevention by Aggressive Reduction of Cholesterol Levels) trial showed a trend toward an increased rate of ICH with statin therapy. 28 However, a post hoc analysis revealed that the highest risk was linked to previous hemorrhagic stroke, and there was no relationship between ICH and low‐density lipoprotein cholesterol levels. 29 , 30 In the present study, we found that statin therapy was associated with a lower risk of ICH.

In Cluster II, the DEGs showed a trend of increased expression and were identified to be related to the deposition and formation of SCW, biosynthesis of secondary metabolites, various transport pathways, and signaling pathways, and as those dramatically enriching lignin biosynthesis, transport of nitrogen compounds, and transmembrane transport of amino acids, like the PAL gene (PH02Gene27016) and LAC gene (PH02Gene03534).

In a phase II clinical study focusing on head and neck cancer that enrolled seven NPC patients, sorafenib was well tolerated and showed a trend of longer time to progression, but this was not statistically significant. 298 The combination of sorafenib, cisplatin, and 5‐fluorouracil was shown to be tolerable in 54 recurrent/metastatic NPC patients, but the contribution of sorafenib to the chemotherapy was not clear. 299 In a phase II trial of pazopanib in 33 patients with recurrent/metastatic NPC, the partial response rate was 6.1%, with the clinical benefit rate of 54.5%. 300 Sunitinib was assessed for its efficacy and safety in 14 pretreated recurrent/metastatic NPC patients.

High SREBP1c also showed a trend of association with poor survival, although not statistically significant (Figure 4C ).

Indeed, our analyses showed a trend of T cells to move towards tumor cells following CXCL12 inhibition in all patients that were classified as tissue responders ( figure 6E ).