Acute phase LADSS Group 3 also showed a trend of association with poor LVEF recovery after Bonferroni correction (Model 1: β = −4.8, p = 0.04), but this trend of association was no longer observed after further adjusting for LGE scar amount in Model 2.
LA Total -GLS and LA Conduit -GLS showed a trend towards significant difference between non-hypertrophied cFD patients without LGE (LVH-/LGE-) and controls (32 ± 8%(LA Total -GLS) vs. 38 ± 5%(Controls), p = 0.04; 21 ± 5% (LA Conduit -GLS) vs. 24 ± 4% (Controls), p = 0.05, Fig. 3 C,D).
The US cohort showed a trend towards less pronounced CRS events (p=0.04).
While DOACs showed a trend toward reduced mortality (RR: 0.90, 95%CI: 0.81-0.99, p=0.04), the marginal significance and confidence intervals approaching the null value suggest a modest effect.
Further analysis of the normal group revealed no significant gender differences in GLS (p=0.12 ), but age stratification showed a trend toward declining GLS with advancing age (p=0.04 ).
In our study, IMRT had a lower V95% than VMAT (98.66±0.01 vs 98.9±0.02, p=0.08), which showed a trend towards statistical significance, but with a higher Dmax in VMAT (74.09±0.6 vs 74.5±1.11, p=0.04), which was statistically significant and higher D2 in the VMAT arm (71.9±0.58 vs 73.2±0.66), which was highly statistically significant (p=0.02).
Ten patients with FTP 2 were responded after and showed a trend of a superior response than those with FTP 3–4 (10/11 vs. 14/25, p = 0.041), indicating that a higher FTP may predict an increased risk of nonresponse to CCT.
Within the BD group, subjective distress correlated with RSQ anger (ρ = –0.65, p = 0.012, q = 0.025) and showed a trend-level association with RSQ anxiety (ρ = 0.55, p = 0.041, q = 0.05), whereas no significant correlations were observed in controls.
Results A univariate analysis showed that CD133 expression in male patients at the late stage (II and III) was significantly associated with worse progression-free survival (PFS) ( P = 0.0057) and overall survival (OS) ( P = 0.015), and a multivariate analysis showed a trend toward worse OS ( P = 0.041).
Increasing maternal age showed a trend toward reduced live birth in multivariable models (all adenomyosis: aOR 0.88 per year, 95% CI 0.77-0.99, p=0.042; direct marker analysis: aOR 0.86 per year, 95% CI 0.75-0.99, p=0.037).
Within the compartment-consistent set, the only BH-significant association was Vorinostat (HDAC pan; KW P = 0.003, BH P = 0.035) with C3-favored sensitivity ( Figure 5D , left panel); Crizotinib (ALK/ROS1/MET) showed a trend-level signal (KW P = 0.042, BH P = 0.14; Figure 5D , right panel). 4.
IL-6, IL-10, and IL-15 concentrations showed a trend towards higher levels in the amelanotic OMM samples (4.22 pg/mL and 0.74 pg/mL, p = 0.042; 13.21 pg/mL and 1.67 pg/mL, p = 0.038; 3.89 pg/mL and 0.71 pg/mL, p = 0.066, respectively; Table 11 ).
Preterm delivery (PTD) showed a trend toward lower rates in the LMWH group; this was statistically significant in the one-sided Fisher’s exact test ( p = 0.042), although not by chi-square ( p = 0.089).
Furthermore, patients in group A showed a trend to lower PD-L1 TPS values ( p = 0.042–0.452 for various cut-off values, Table 1 ), which was also associated with poorer response to ICI therapy in the current (Supplementary Table 1) and previous studies [ 30 ].
Moreover, 3D LV radial strain showed a trend toward reduction in the obese group (36.1 ± 5.2% vs. 38.6 ± 4.1%, p = 0.043), though this does not survive correction for multiple comparisons and should be interpreted cautiously.
PCoA analysis of the bacterial community showed a trend toward separation based on ripening stage, although with substantial overlap among groups (R = 0.2153, P = 0.043).
When grouping cases with mTLS and/or LA together in PTs or pMets, positive cases showed a trend, not reaching statistical significance, toward longer OS but not PFS in pMets (Log rank p = 0.043 and 0.34).
At 10 mo, Rer1 showed a trend towards a significantly reduced expression in 5XFAD female mice (Fig. 5 K) (Genotype: F(1,10) = 5.315, p = 0.044; RGs: F(2,20) = 0.402, p = 0.674; Genotype*RGs: F(2,20) = 0.537, p = 0.593).
This showed a trend towards improved survival for patients with baseline sSema4D < 41.74 ng/mL (log-rank 4.045, p = 0.044; Figure 3 B).
Positive surgical margin rates showed a trend toward improvement over time ( χ 2 = 12.9, df = 6, p = 0.044).
Divergence emerged over time: at 4 and 5 months the tUS– group showed a trend toward lower DI values compared to tUS+ (p = 0.044 and p = 0.017 uncorrected; Bonferroni-adjusted p = 0.265 and p = 0.101, respectively).
Although we did not observe a 3‐way interaction of group × condition × response ( F (3,105) = 2.041, p = 0.113, partial η 2 = 0.055), we observed that irrespective of the stimulus condition the low perceivers showed a trend towards increased confidence in reporting the absence of the target compared to the high perceivers (significant group × response: F (1,35) = 4.382, p = 0.044 partial η 2 = 0.111, with post hoc pairwise comparisons yes: F (1,35) = 0.698, p = 0.409, partial η 2 = 0.020; no: F (1,35) = 2.696, p = 0.110, partial η 2 = 0.072) (Figure 3E ).
In the stationary pattern condition, post hoc analysis showed a trend toward an increased PPD ratio [uncorrected p = 0.044; corrected p = 0.088], whereas no significant difference was observed in the moving pattern condition (uncorrected p = 0.230; corrected p = 0.460) (Fig. 3 B).
Further analysis showed a trend towards a higher utilization of non-excisional techniques in males ( p = 0.045) and a significant association between co-morbidities and the use of excisional techniques ( p = 0.049) (Table 1 ).
Analyses on specific metabolizer phenotypes showed a trend for higher frequency of CYP2D6 ultrarapid metabolizers (UMs) in remitters compared with non-remitters in patients with TRD (χ 2 = 4.76, p = 0.045), but not in patients without TRD (χ 2 = 0.02, p = 1.00, Supplementary Table S9 ).