However, longer incubation showed a trend of higher toxicity of DAC, especially in mWT1-C1498 cells when comparing IC 50 of two drugs at two time points.
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Concerning IHCs, the damage showed a trend similar to OHC loss ( Figs. 2C-D ).
NT-proBNP showed a trend towards a higher level in the PLA group in comparison to the PIO group, but levels fluctuated very strongly during the study.
Further, our post hoc analysis showed that patients with mild depression (MADRS >12) showed a trend towards more utilitarian responses compared to the subjects without mild depression (MADRS <12).
The transcription levels of IL-6, IL-8, IL-13, IL-17, and IFN-γ showed a trend of being downregulated in the jejunum of infected animals compared to the negative controls,.No immune cell recruitment could be seen after infection, and no intestinal pathologies, such as villus shortening or increased levels of apoptosis.
In addition, the model showed a trend for impact factor, where a 1 unit increment in impact factor showed an observation of 102.2% more key methodological items present.
Drains themselves showed a trend indicating that they may augment infection rates.
Yet some test measures showed a trend towards improvement from oral β-alanine intake [ 55 ].
While the group observing the real aquarium showed a trend for lower heart rate and muscle tension as well as for an increase in skin temperature, none of the group comparisons reached statistical significance.
The subgroup of patients with optic nerve injuries showed a trend towards a visual field expansion of 5.8° (± 1.2) in the VRT group compared to 4.3° (± 0.7) in the placebo group [ 11 ].
The '11+' [ 31 ] results showed a trend towards reduced risk of MTSS and undefined ankle injury; however, these were not convincing enough to conclude their effectiveness in injury prevention.
The combination treatment of BTZ with toyocamycin, either at 0.5 mg/kg or 1.0 mg/kg, showed a trend toward enhancing anti-tumor activity represented as smaller tumor volumes when compared with BTZ or toyocamycin alone ( Figures 6a and b ).
One study used perfused rat livers after PH and showed a trend toward decreased de novo lipogenesis as compared with controls. 28 Furthermore, mitogen stimulation of cultured primary rat hepatocytes leads to decreased lipogenesis. 33 Hepatic lipid metabolism is likely to be regulated by numerous factors in the regenerating liver, 27 , 31 and our data indicate that the effect of cyclin D1 is to diminish lipogenesis.
14) However, against our expectation, the patient group with collateral grade 0/1 had higher LV ejection fractions and showed a trend toward lower Killip class compared to the patient group with collateral grade 2/3.
Retrospective subset analyses of TROG 02.02 showed a trend for improved outcomes of patients with p16− tumors treated with cisplatin and the hypoxic cell sensitizer tirapazamine compared to cisplatin alone [ 16 ].
When blood pressure was analyzed in mIGF-1 Tg; SIRT1 CKO mice, DBP showed a trend of increase compared to WT, although this was not significant and was to a lesser extent when compared to mIGF-1 Tg mice (Fig. 5 ); SBP on the other hand was found restored to WT level in mIGF-1 Tg; SIRT CKO mice (Fig. 5 ).
In one study the unilateral airflow wcorrelated with verbal-spatial task performance in 23 right-handed men.[ 7 ] In another study, the effect of thirty min of unilateral forced nostril breathing was studied in 51 right handed volunteers.[ 8 ] Spatial task performance (a right hemisphere specific task) was significantly increased during left nostril breathing, while verbal task performance (a left hemispheric task) showed a trend of increase during right nostril breathing.
7 Niacin was the only agent tested in the Coronary Drug Project that showed a trend for efficacy. 8 A meta-analysis of 22 trials showed that old lipid-lowering agents failed to prevent cardiovascular events. 9 Moreover, older lipid drugs were associated with higher risk for mortality by accidents and violence, 10 leading to the discredit of the beneficial effects of lipid-lowering
SNPs with p<0.0031 or 0.0031<p<0.1 were considered to be significantly or showed a trend of being associated with disease risk respectively.
Non-basal values of 129P2 mice showed a trend to be higher than those of basal levels, although this difference did not reach significance (t = −2.602, p = 0.032, corrected p<0.0167).
In lymphocyte cell RNA, from individuals of known rs11573156 genotype, there was no allelic RNA expression difference for exons 5 and 6, but G allele carriers (n = 7) showed a trend to lower exon 1–2 expression compared to CC individuals.
Patients with suboptimal response at 12 months showed a trend toward lower EFS; those with suboptimal response at 18 months had a treatment-free survival comparable to optimal responders.
Surface roughness analysis showed a trend of smoother interface when cutting the cornea after the shortest deswelling time (0 hours) (IS and RAS analysis) (RAS 0 hours: 16.5 [mean], 16.1[median], standard deviation 1.1; RAS 48 hours: 17.4 [mean], 18.3 [median], ±2.9; RAS 72 hours: 21.0 [mean], 22.5 [median], ±6.0 ; IS 0 hours: 2.8 [mean], ±1.5; IS 48 hours: 2.9 [mean], ±0.7, IS 72 hours: 3.4 [mean], ±1.0) (see Figure 3A and B ).
However, immunization with TcpF+CTB was highly protective and showed a trend toward greater protection than immunization with CTB alone (82% vs 64% survival).
There were 30 eyes with OAG and 5 eyes with OHT for this analysis, and the results also showed a trend toward better IOP response at each time point for the OHT group, but the result was not significant ( P < 0.182).