Patients carrying the IL1RN CTA haplotype had significantly lower SF mean levels of IL10 (p=0.034), and showed a trend towards lower levels of IL1β and IL6 ( table 4 ).
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WAT from N2KO mice showed a trend for higher expression levels of the macrophage markers EGF-like module-containing mucin-like hormone receptor-like 1 (Emr1) (1.66-fold higher) and Cluster of Differentiation 68 ( CD68 ) (1.87-fold higher) in N2KO mice respectively when compared to WAT from WT mice ( Fig. 5A ).
In our analysis of OED group, they did not show a significant PFS difference between patients with chemotherapy plus rituximab and those with chemotherapy alone, but only showed a trend of improved OS for patients treated with chemotherapy plus rituximab.
Of the tested variants, the risk variant in HHEX showed a trend towards a low birthweight and the risk variant in the CDKN2A/2B locus was associated with high birthweight.
As for the MMP1 −1607 1G/2G polymorphism, a Greek study showed a trend for association with exfoliation syndrome [ 37 ].
In the present study, the analyses showed a trend toward favoring the use of cryoablation than the microwave ablation in terms of the restoration and maintenance of sinus rhythm during a long-term follow-up.
However, after 48 hours, HD ASCs showed a trend toward being slightly higher in number than normal ASCs (Fig 1).
We found that treatment with anti–Tim-3 alone had little or no effect and treatment with anti–PD-L1 alone showed a trend toward delayed tumor growth, but this varied between experiments and did not reach statistical significance ( Fig. 5 ).
In the case of the interaction with BMI, the results showed a trend opposite to the original expectations: across models and adjustment sets, smoking intensity was associated with higher γ-GT in subjects with normal weight but not in obese subjects, with effect estimates being of intermediate magnitude in subjects with BMI 25 to <30 kg/m 2 ( Table 5 ).
The results showed a significant reduction in micturition frequency in men; however, the remainder of assessed outcomes showed a trend toward improvement without reaching significance.
Interestingly, many works demonstrated that ADSCs not genetically-altered to express specific factors also showed a trend for increased neuromuscular function and increased survival, potentially through trophic factors that ADSCs themselves naturally provide [ 16 ], [ 17 ].
Moreover, the vestibular group showed a trend of higher mean values for FC, DS, ST and CV and lower values for Sw in both single and DT conditions than controls, even if between groups differences were not statistically significant.
All animals showed a trend of spending more time in the target quadrant of the swimming pool.
IM plasma levels showed a high inter-patient variability, and low IM plasma exposure (minimum concentration [Cmin] <1100 ng/mL) showed a trend of low rate of objective response and a rapid evolution of resistance (short time to progression).
Other-directed movements showed a trend in the opposite direction, increasing over the interval considered.
Higher apoE levels were also associated with increased Th1 cytokine secretion, as the serum cytokine profile showed a trend towards greater Th1 cytokine concentrations (TNF, IL1- β , and IFN- γ ) in septic, induced mice compared to septic, noninduced (low apoE) mice [unpublished data].
Compared with controls, EIPH-affected horses showed a trend to a hypercoagulable state (shorter times of clot activation and higher clot firmness for most of the considered tests) before the race, when, however, many differences were not statistically significant, likely due to the individual variability.
The use of alcohol progressing to dependence in more than three years in late onset group but in only less than one year in early onset group, is another evidence for special need for substance abuse in general and sedative abuse in particular in early onset group Complications: Despite an overall similarity between the two groups, the early onset group showed a trend for more legal and less social 155 BISWAJITDEeta/. problems.
Patients in the high risk arm with large localized tumors showed a trend toward improvement with the addition of etoposide, but this trend did not reach statistical significance [ 132 , 133 ].
For the 24-hour recordings, the pNN50-effect seen with the EC- and OC-averages of 24-47 hours before the recording showed a trend towards a stronger effect in individuals not taking beta-adrenergic receptor blockers (data not shown).
After 18 h, a large amount of PC3 treated cells was still present in late S and G2/M phase, whereas LNCaP, as expected, showed a trend to accumulate in S phase ( Figure 2C ).
Whereas yeast strains mutated in UBC12 and PAS3 showed a trend for extended lifespan, this did not reach statistical significance.
As expected, due to the strong correlation between ACPA and HLA-SE , carriage of HLA-SE alleles also strongly associated with erosive disease at 5 years ( Table 2 ). Only 2 of the 18 SNPs tested showed a trend towards association with the presence of erosions by Year 5.
In addition, we also found that with an increase in oxygen free radical contents in the pancreas, hormone levels showed a trend to increase; thus, we presume that on one hand, excessive free radicals may lead to oxidative damage of islet cell, while on the other hand, increase of oxygen free radicals may induce secretion of SS, which is attributed to SS’regulatory effect. 5.
Of note, EPA and ALA non-significantly lowered the expression of the ABCA1 gene, while CLA showed a trend for higher expression ( Figure 2 ).