“showed a trend”

However, when all subjects were considered, we found a significant correlation between the RPRE-M and AL change for the first year, and the regression line showed a trend for an inverse relation between a lower refractive increase and more myopic defocus in the nasal and temporal eccentricities.

The present study also showed a trend for an increasing gradient of total ApoB concentrations ranging from ApoE2/2 carriers to ApoE4/4 carriers; this result replicates previous work [ 28 ].

Kaplan-Meier plots of poorly differentiated prostate cancer entities (ranked Gleason 8–10) also showed a trend towards longer recurrence-free patient survival for MB-positive cases [ 18 ].

R-naproxen pretreatment of Swiss 3T3 cells for 1 h also showed a trend of dose-dependent inhibition of EGF-stimulated Cdc42 activation, which was maximal at 300 μM drug and comparable to treatment with 10 μM of Cdc42 specific inhibitor CID2950007/ML141 ( Fig 2B ).

According to a nation-wide phylogeographic analysis, 3b showed a trend for migration from the southwest to other regions, which is consistent with the known drug trafficking route in which Yunnan links the Golden Triangle to the inland of China.

In addition to an increased occurrence of hypertension, patients with the variant allele in IL8 rs1126647A>T showed a trend towards improved PFS/OS (22 vs 14 months for median PFS and 40 vs 25 months for median OS), although the differences between groups did not reach statistical significance.

Kaplan-Meier analysis showed a trend in shorter OS for patients with RRM2, TS, and ERCC1, BRCA1 overexpressed tumours.

Likewise, patients who had lower HGF or VEGF 121 levels also showed a trend toward improved ORR versus patients with higher levels, though the interaction test did not show enough power ( Table 3 ).

The LD showed a trend to decrease body weight in Elovl6 +/+ Ldlr −/− mice and to increase body weight in Elovl6 −/− Ldlr −/− mice.

The metabolic profile of the combined IFG/IGT group showed a trend towards similarity to the type 2 diabetes group.

Although cells cultured for 4 days on BM-ECM showed a trend toward greater numbers of MSCs, it never attained statistical significance.

spicata height ( Table 1 ; Fig 6b ; S1 File ), although average height showed a trend of being highest in canopy microsites, followed by edge and interspace microsites: canopy x ̄ = 28.8 cm ( σ x ̄ = 2.4 ) , edge x ̄ = 27.6 cm ( σ x ̄ = 2.5 ) interspace x ̄ = 22.8 cm (σ x ̄ = 2.3) .

Furthermore, in our assay, acute and chronic CRF01_AE, and C showed a trend of higher inhibition with increasing concentrations of the virus.

Despite the limited samples size in the present study, several previously reported associations for case control status were replicated at p≤0.05 and all published SNPs that were in the dataset showed a trend for association ( Table 4 ).

Phosphorylation at tyrosine 488 (p-c-Src418), the c-SRC activating phosphorylation site, was significantly increased and phosphorylation at tyrosine 530, the c-SRC inactivating phosphorylation site, showed a trend to be decreased under stiff conditions (Figure 1B ).

Surprisingly, heat-stressed intertidal Acropora showed a trend of up to 26% lower tissue biomass than the controls whereas heat-stressed subtidal Acropora were able to maintain their tissue biomass ( Fig. 5D ).

ADAMTS19 methylation associates with local, but not with distant, CRC metastases ADAMTS19 hypermethylation was frequent in adenomas and showed a trend for decreasing frequency during tumor progression (Fig. 5a ).

Since all of these parameters showed a trend towards alterations consistent with impaired insulin sensitivity, we cannot exclude that the number of studied animals (n = 5) was too low to unravel significant DEHP effects on additional parameters of insulin resistance and impaired glucose metabolism.

Even though the difference was not statistically significant, also NK cells showed a trend toward increased frequency in the population of hematopoietic cells infiltrating the tumors of Dexo(B16 + pIC)-treated mice (15.5%) as compared to mice administered with saline or the other Dexo formulations ( Fig. 5f , middle).

Biochemical analysis of collagen content by the sircol assay showed a trend for increased collagen content in the lungs of rats treated with Si NW at 91 days post-exposure with a significant increase of collagen in the 250 μ g dose of Si NW when compared to control rats ( Figure 8 ).

Interestingly, in lean mice chronic THC showed a trend to reduce whole gut transit, shortening the time taken for the blue marker to be defecated.

The DTI score, which quantifies the number of VPs per investigated surface area, showed a trend toward higher mean values in the carriers of FLG mutations compared with FLG wild-type subjects at week 0 (427.0 and 336.2, respectively) and after 6 weeks of therapy (296.6 and 224.3, respectively), although the differences did not reach statistical significance (data not shown).

Caspase genes (CASP 4, 6 and 8) and other signaling pathway genes important for inflammation (MAPK1, MAPK13, IRF1 and NLRX1) also showed a trend of increased expression at the hepatic phase ( Table 2 ).

43 With the TCGA breast cancer data set, higher expression of NSD1 showed a trend toward better overall survival when all tumor subtypes were considered ( Figure 6c ) and significant survival advantage in HER2-negative patients (135 high and 134 low expression cases, Figure 6d ).

BG particles showed a trend towards increased cell survival with ZA treatment; however, interpretation was confounded by the decreased cell numbers seen with BG alone.