“showed a trend”

The present study did not reflect recurrence and prognosis; nevertheless, the univariate analysis of RFS showed a trend toward recurrence ( p = 0.051).

However, the tumor grade group G2 + G3 showed a trend towards worse OS compared to G1 (HR=2.386, 95% CI 0.994-5.727, p=0.051).

This showed a trend towards a higher proportion of CD8 naive cells in both scRNA-seq and flow cytometry data ( P = 0.051 and P = 0.065), suggesting microenvironmental differences between the two NPM1 classes affecting the T cell composition already at diagnosis.

Type 1 MNV showed a trend ( p =0.051) towards smaller probability for the correct detection compared to all other subtypes.

In soft tissue AS, combined PD-1 and PD-L1 expression showed a trend toward poor survival ( p = 0.051), whereas in UV-associated AS, PD-1 expression correlated with better survival ( p = 0.035).

However, patients positive for either or both SEPT9 and SHOX2 methylation showed a trend towards worse prognosis compared to methylation-negative patients, particularly when analyzing the cellular fraction ( p = 0.051) (Fig. 3a ) although statistical significance was not reached.

Regarding gender, the distribution showed a trend ( χ 2 (5) = 11.02, p = .051, Cramer's V = .21).

On the other hand, JAG1 gene SNPs rs2235811 and rs2275811 showed a trend to association with FN-BMD and LS-BMD ( p = 0.051 and 0.089, respectively); well above the multiple test-significance threshold estimated at 0.009.

Among 48 patients receiving 3L therapy, regorafenib showed a trend toward improved OS over sorafenib (HR, 0.33; 95% CI, 0.11 to 1.02; p=0.051), supported by restricted mean survival time analysis (p=0.028).

However, we observed that positive PD-L1 immunostaining in TCs showed a trend of worse overall survival despite not achieving statistical significance ( p = 0.051) ( Figure 3 ).

Further experiments using a small interfering RNA (siRNA)-mediated knockdown approach also showed a trend toward reduced SOX9 mRNA levels in PGR siRNA-treated hGLCs ( p = 0.051), consistent with PGR-dependent control of SOX9 transcription ( Figure S2 B).

Clinical Correlation The GMV alteration in the right putamen significantly positively correlated with the HAM-A score ( r = 0.44, p < 0.05; Figure 1B ), while the GMV alteration in the left IPL showed a trend to was negatively correlated with the HAM-A scores ( r = −0.39, p = 0.051; Figure 1C ).

Additionally, although higher CLR showed a trend towards increased mortality (OR 1.03, p = 0.051), it did not reach statistical significance in the multivariate analysis. 3.4.

Among these patients, Cys C was significantly decreased in follow-up period [1.01 (0.81-1.31) mg/L versus 0.97 (0.69-1.20) mg/L, p = 0.017] whereas estimated GFR showed a trend to increase (p = 0.051) (Table 3 ).

After adjustment, higher preoperative PVR (adjusted OR 1.25 per 1 WU increase, 95% CI 1.03–1.52, p = 0.024), higher LAS (adjusted OR 1.06 per 1-point increase, 95% CI 1.04–1.08, p < 0.0001), and higher intraoperative mPAP (adjusted OR 1.1 per 1 mmHg increase, 95% CI 1.05–1.16, p < 0.0001) remained independently associated with intraoperative MCS use, while right-sided transplant showed a trend toward independent association (adjusted OR 2.26, 95% CI 0.996–5.107, p = 0.051).

Age showed a trend-level effect (HR 0.96, 95% CI 0.92–1.00, p = 0.051) (Table 2 ).

Lithium-treated WT mice showed a trend towards being less immobile than other WT groups (F 2,60 = 3.13, p = 0.051).

In addition, dietary RE showed a trend in influencing the water-holding capacity in leg muscle of meat ducks ( P = 0.051).

Independent predictors included ECOG 0 and thoracic spine V 5 < 57.3%; planning target volume < 210 cm 3 showed a trend toward association ( p = 0.051).

The number of recurrences showed a trend for an association with additional resection ( p = 0.051).

FGF21 showed a trend ( p = 0.051) in overall change in participants following the LCHF diet after decreasing from a median (IQR) of 148.16 (203.49) to 99.4 (92.43) pg/mL at week 4 and increasing again to 167.38 (152.08) pg/mL at week 8, with post-hoc analysis reporting a trend ( p = 0.069) between baseline and week 4, whereas no change was observed in HCLF.

When the percentage of animals that explored the objects on day 4 was examined, the animals under HU showed a trend toward a lower percentage (27%) than animals without HU (48%) ( z (1, 3.805) = 1.951, p = 0.051, two-sided chi-squared test) or animals under the control HU condition (50%) ( z (1, 3.732) = 1.932, p = 0.053, two-sided chi-squared test). 3.3 Plasma metabolomics analysis When the effects of radiation were analyzed in the plasma of animals without HU or control HU, the riboflavin metabolic pathway was affected most along with glycerophospholipid, sphingolipid, and glutathione metabolic pathways being less affected in the comparison of sham irradiation vs. 0.75 Gy ( Figure 4A ).

The VAS, with anchors ‘Attentive' and ‘Dreamy', ( Figure 4 c ) showed a trend for a main effect for ( p =0.051) and a significant 3-way interaction ( p <0.01; Figure 4c ).

In this dataset, the LumB subtype showed a trend towards higher event rates in the high CCJ signature group during the first 0–5 years ( p = 0.051), and a similar pattern was observed in the Basal subtype ( p = 0.091) ( S4 Fig ).

The variant rs112076606 (A/G) showed a trend toward a significant association with both BMIC and UIC ( P = 0.051 and P = 0.081).