IL-6 and CRP were positively associated with high nuclease activity of isolates ( P < 0.001 and P = 0.049, respectively), while S100A8/9 showed a trend ( P = 0.051) indicating that in inflamed airways, S. aureus isolates with high nuclease are selected, thereby presumably facilitating escape from NETs ( 18 , 19 ).
Further experiments using a small interfering RNA (siRNA)-mediated knockdown approach also showed a trend toward reduced SOX9 mRNA levels in PGR siRNA-treated hGLCs ( p = 0.051), consistent with PGR-dependent control of SOX9 transcription ( Figure S2 B).
The interaction of time x basepower showed a trend ( F 3, 75 = 2.703, p = 0.051, η2 = 0.098), while the factor group ( F 1, 25 = 0.931, p = 0.344, η2 = 0.036) and the interaction time x mismatch did not reach significance ( F 3, 75 = 1.478, p = 0.227, η2 = 0.056).
Model comparison showed no effect of imagery type of pages for the French texts (Estimate=0.014, t =0.718, χ 2 =0.510, p =0.475), while it showed a trend for the Davis texts (Estimate=-0.029, t =-2.046, χ 2 =3.800, p =0.051).
Moreover, we found that levels of cortisol (hydrocortisone) showed a trend for association with disability measured by EDSS after 2 years of follow-up ( p = 0.051, ANOVA test).
The PKG2 R242Q -expressing osteoblasts showed a trend toward higher BrdU incorporation ( P = 0.051) and significantly reduced cleaved caspase-3 staining compared with WT osteoblasts under basal conditions ( Figure 2, A and B ).
1 l); the DI was significantly greater than 0 in Septin5 +/+ mice (one-sample t test, p = 0.022) and showed a trend in Septin5 −/− mice ( p = 0.051), and no significant genotype differences were observed in either the preference index or DI (Fig. 1 l).
The Kruskal–Wallis test showed no effect of LPS, and the multiple comparisons only showed a trend in the difference between 50 and 800 μg/mL LPS ( p = 0.051).
When analyses were adjusted by line of treatment and recruitment country, two more variables — age under 12 years old and having an inflammatory phenotype — showed a trend towards improved response ( p = 0.051 and p = 0.085, respectively) (Table 6 ).
Meanwhile, MDD patients showed a trend of impairment in the dimension of working memory compared with HCs ( t = −3.796, p = 0.051, Bonferroni corrected).
For the traditional section, however, the only significant predictors were prior GPA and ethnicity (note type was not analyzed for this section), although class standing showed a trend ( p = 0.073), and major had borderline significance ( p = 0.051).
In soft tissue AS, combined PD-1 and PD-L1 expression showed a trend toward poor survival ( p = 0.051), whereas in UV-associated AS, PD-1 expression correlated with better survival ( p = 0.035).
Nevertheless, patients with high‐risk cytogenetics showed a trend toward lower 3‐year PFS than those without (77.8% vs. 89.4%, p = 0.051), and ultra‐high‐risk cytogenetics (≥2 high‐risk cytogenetics) had an even worse prognosis, with 61.2% 3‐year PFS.
Treatment with LFPRLR SMO also showed a trend towards reduction of Tregs in the liver, which is a major site of metastatic spread ( p = 0.0511).
Between the TZ and PZ, only the 2CU model parameter F p ( p = 0.0245) and the exponential EMM parameter α ( p = 2.10 × 10 −3 ) showed differences, while the 2CU model parameter E showed a trend to significance ( p = 0.0512).
However, the first-generation vaccine recipients showed a trend towards higher IgG levels compared to negative controls (p = 0.0513, ns, Fig. 4 B).
The pasture accumulation rate showed a trend ( P = 0.0513) for greater values in the Tall than in the Short treatment, and significant correlations with ingestive behavior variables, like IT ( r = 0.63, P < 0.0001) and GT ( r = −0.49, P < 0.0001).
Recipients of TCD-BM from CD11c-p28 f/f mice and T cells from WT mice (hereinafter referred to as KW) showed a trend of shortened survival compared with the WW group ( P = 0.0514), suggesting that donor DC-derived IL-27 p28 deficiency also contributes to the exacerbated aGVHD, albeit to a lesser extent (Fig. 3a ).
A two-way analysis of variance (ANOVA) showed a trend towards a significant interaction (p = 0.0514) between island composition (sucrose versus no sucrose) and egg-laying zone, suggesting that the presence or absence of a sucrose island influences the distribution of egg laying across the plates.
When analysed according to HIV status, HIV- women who delivered preterm showed a trend for lower γδ T cell frequencies than HIV- women who delivered at term and this was particularly evident in the first trimester (p = 0.0515) ( Fig 4F and 4G ). γδ T cell frequencies were also lower in the first trimester in HIV+ women who delivered preterm compared to HIV+ women who delivered at term, but this difference was not statistically significant ( Fig 4F ).
In CBDB/NIMH (Clinical Brain Disorders Branch/National Institute of Mental Health Sibling Study) sample (n = 188), rs3916441 also showed a trend of association (p = 0.0516) ( Table 1 ).
HbAS RBCs showed a trend toward reduced PTR compared to HbAA Townes controls (P = 0.0518; Figure 7C ).
Additionally, m6A levels showed a trend toward being higher in patients with T4-grade disease ( P = 0.0518; Fig. 1 D) and those with perineural invasion ( P = 0.0568; Fig. 1 E).
While no significant changes were observed in other enzymatic activities, β - N -acetylglucosaminidase, which hydrolyzes the β -1,4 or β -1,3 bonds between N -acetylglucosamine residues in host glycans and glycosaminoglycans, showed a trend of lower activity in the prebiotic group at month 6 ( p = 0.0518, Figure 4B , Table S12).
plantarum PFM105 treatment showed a trend toward increased villus length over the antibiotic treatment ( P = 0.0518) in the ileum ( Table 2 ), while it had little effect on crypt depth and the ratio of villus to crypt in the ileum.