Excerpts

For GR activity, the statistical analysis revealed a significant main effect for the group, which was almost significant (H = 5.655, p = 0.052).

ST32db showed a trend toward decreasing SREBP1 protein levels relative to the control group ( p = 0.052).

On the other hand, NK-cell mediated viral suppression was 34 ± 7% in the presence of PRO (increased in 8/10 donors) and 37 ± 4% with ROM/PRO combination (increased in 7/10 donors), this latter being higher than in ROM-treated and untreated co-cultures in a statistically significant and nearly significant ( p = 0.052) manner, respectively ( Figure 5 B).

There was also a strong trend towards an increase in Young Adult Sleep Dis rats than Young Adult Normal Sleep rats ( p = 0.052).

In contrast, CD34 displayed higher sub-umbilical scores (median 3) compared with supraumbilical (median 2), with a strong trend toward significance ( p = 0.052) and a large effect size, suggesting increased microvascular density/activation in the sub-umbilical segment.

Testosterone levels were lower in male CRC patients (median 14.32) compared with healthy controls (median 17.69), with a trend toward significance ( p = 0.052; Mann–Whitney test).

One study observed that the levels of serum IL-6 in patients with alcohol dependence did not significantly decrease although they showed a trend from baseline to 16-week follow-up ( p = 0.052) [ 70 ].

This effect is quite close to significance (test for trend, p = 0.052).

Ligands showed similar expression in cuprizone-treated and control samples, except for the increased expression of two genes—Plau (plasminogen activator urokinase) and Spp1 (secreted phosphoprotein 1)—which showed borderline significant differences in expression ( Table S15 , adjusted p -value = 0.052).

According to the plotter, M6PR-high patients show a strong trend towards increased survival [HR:0.64 (0.45–1.01), p = 0.052], when including patients from all stages; and a significantly increased survival in the case of advanced-stage (III–IV) GC patients [HR:0.63 (0.42–0.95), p = 0.026].

Although no correlation was observed between the sCD163 levels and TNM stage in a Spearman’s rho correlation test ( p = 0.141), an intergroup analysis revealed that patients with TNM stage IV tumors showed a trend towards higher sCD163 levels compared to TNM stage 0/I patients ( p = 0.052, Figure 2 B).

Generally, there was a strong trend for lower CS activity in SY5Y-APP695 cells compared to SY5Ymock cells ( p = 0.052).

Factor B (FB) levels on postoperative day 2 (V2.2) showed a trend toward significance, with lower concentrations associated with higher CAM-S scores (β = −0.549, p = 0.052; R 2 = 0.302).

A recent phase II trial for patients with residual disease or high-risk pCR after receiving neoadjuvant or postoperative anti-HER2 agents reported that the GP2 vaccine had no significant benefit in DFS in the total population, yet a subset analysis showed a trend toward improved DFS in the HER2+ group that received the GP2 vaccine ( p = 0.052) [ 46 ].

We observed an almost significant reduction in neuroblast surveillance in the SGZ of male mice fed with n-3 PUFA-deficient diet ( p = 0.0521) compared to male mice fed with the balanced diet, as well as a trend toward reduction in the GCL of male mice compared to females ( p = 0.0594), both fed with the n-3 PUFA-deficient diet ( Figure 7 b).

The history of positive repeated TUR (re-TUR) (HR: 4.93, p -value = 0.0001) and T1 tumor stage (HR: 2.04, p -value = 0.0159) were associated with shorter RFS, while G3 tumor grade according to the 1973 WHO classification showed borderline significance (HR: 1.83, p -value = 0.0522).

The association between the SERP2 gene and the 0–6 h effect-site MEC was marginally significant (adjusted p = 0.05245; Supplementary Table S5 ).

Although the time course of left ventricular ejection fraction (LVEF) showed a trend toward reduction in the sham compared to the V-V ECMO group after the end of the experiments, the difference failed to reach statistical significance ( p = 0.053). 2.3.

However, it should be mentioned that borderline significance was obtained for alleles of POLG c.-1370T > A (rs1054875) ( p = 0.053). 2.4.

For ELISA, the dementia group showed a trend of lower Aβ1-42/Aβ1-40 (0.051 ± 0.021 vs. 0.062 ± 0.022, p = 0.053) and higher t-Tau (594 ± 502 vs. 313 ± 145, p = 0.028) and p181Tau (81 ± 46 vs. 56 ± 22, p = 0.034) than the MCI group.

No significant differences were observed for circGrin2b, circCnot6l, circRtn4, circPrex2 or circSlit1 for female animals, although circSlit1 had a strong trend for upregulation ( p = 0.053).

A two-way ANOVA revealed a significant STRESS × PEPTIDE interaction for the time spent in the enclosed sector-2 and the percentage of entries in the enclosed sector-2 (F2,52 = 3.25; η2 = 0.12; p = 0.047 and F2,52 =3.42; η2 = 0.18; p = 0.042, respectively), and a marginally significant STRESS × PEPTIDE interaction for the enclosed sector-1 time (F2,52 = 3.12; η2 = 0.11; p = 0.053), without any significant main effects of the factors (F < 1.0; η2 < 0.02; p > 0.40).

In contrast, including plasma samples from BC patients in the statistic tests introduced a certain degree of noise and the mutation c.742C>T in sample 079MS was not detected despite being close to significance ( p -value = 0.053) ( Table S4 ).

The hsa-miR-155-3p target SP4 showed a trend for down-regulation (FC = 0.43, p = 0.053). 3.

Our results do not support this, because a nearly significant ( p = 0.053) elevation of Adcyap1 mRNA expression occurred in the insular cortex that fits well with the observations of Broome et al.