Excerpts

For instance, SNP rs113303918 in the intron of the FHL1 gene is significantly associated with WHR in female and the combined male–female analyses ( P XWAS, female = 6.6x10 –12 and P XWAS, combined = 9.8x10 –14 , respectively), while being only nominally significant in the male-specific analysis ( P XWAS, male = 4.5 × 10 –5 ) and the per-allele effect sizes on WHR are similar in both sexes (effect size ratio = 0.93, SE = 0.26).

However, one can see that the proportion of under- and over-coordinated Ge atoms in the glass models is quite significant.

24 hpf), with a highly significant overlap between the developmentally regulated exons in PGC and soma (Supplementary Fig. 7a , p value 1.12 × 10 –46 , Fisher’s exact test).

Measuring 300 dimers visualised by rotary metal shadowing EM revealed rod lengths ranging respectively from 40.7 to 56.9 nm and from 41.0 to 56.0 for 90% of measurements in Tris and NaPi buffer, with a significant trend towards shorter rods in NaPi buffer: median rod length of 51.1 nm in Tris buffer vs 49.2 nm in NaPi buffer ( p -value 4.45 × 10 −3 ) (Fig. 1b, c and Source Data file).

Overall, all but one variant (p.P528T) affected either KA-evoked current amplitude or rectification or both when co-expressed with GluA1, although in some cases the effects fell short of significance when unpaired t -tests included Holm-Bonferroni correction for multiple comparisons (Fig. 8 , Supplementary Table 8 ).

The average score for each predicted function was calculated by normalising the scores from the individual methods (e.g., e -value or probability) to the range of 0–100, with 100 indicating a highly confident score (e.g., a highly significant e -value from Pfam or Gene3D; see methods).

The level of marginal significance, p -value, was calculated using two-tailed Student’s t test for pairwise comparison and one-way analysis of variance with Bonferroni adjustment for multiple variations.

An important trend in recent years has been to mitigate the speed limitation by simultaneously correcting multiple sub-pupils 17 or sub-areas 18 in the large view field.

Individuals initiating ART within the first year of HIV-1 infection ( n = 173, 16.3%, Table 1 ) showed a trend toward a faster decay of the HIV-1 reservoir in the univariable model than individuals starting after the first year of HIV-1 infection ( n = 884, 87.6%, Table 1 ).

An obvious trend can be seen, indicating possible errors in the ArcticDEM, the baseline, or front-back tilt of the rack structure that supports the antennas.

The critical product Ω* displays a decreasing trend with l (Supplementary Fig. 10 ), that in turn affects the point from which the effect of P and A on C changes from decreasing to increasing returns to scale.

However, a total of 1,399 genes exhibited highly significant differences (2-way ANOVA, False Discovery Rate < 0.01; Fig. 4a, b , Supplementary Data 1 ) by sex chromosome genotype (XX or XY).

Furthermore, levels of transcripts of the repolarizing channel genes KCNQ1 ( encoding Kv7.1) and KCND2 (encoding Kv4.2) were decreased, while the repolarizing channel gene KCNH2 (encoding Kv11.1) showed a trend toward higher levels (Fig. 4e ).

electron density at the 89 Y nucleus) and the spin-dipolar contribution is almost insignificant (hence the vanishing anisotropy) (Supplementary Table 14 ).

In Europe, either loss 13 – 17 and recovery or stability 18 – 21 are reported for seagrass meadows, with an overall trend toward decline reported for the Mediterranean endemic species Posidonia oceanica , which has lost between 13% and 50% of its areal extent since 1960 16 , 17 .

This difference was apparent as early as PD21, the time point at which the first wave of spermatocytes produce spermatids in WT testes.

There was also a mild trend toward a reduction in percentage of NCR + ILC3s among Lin – cells (Fig. 1a, c ), while percentages of ILC2s and ILC1s in Lin – cells were not affected by α-DR3 treatment (Fig. 1a, d ).

There was also a highly significant age trend with rate ratios increasing from 1.47 (95% CI: 1.45–1.49) in those up to 20 years of age to 5.20 (95% CI: 5.15–5.25) for individuals above 60 years.

A marginally significant direct effect of blood glucose on the amount of money shared in the DG is in line with the idea of resource accumulation and consistent with the previous findings.

A decreasing trend of the average initial spin polarization with increasing thickness of the 2D/3D graded samples is observed.

In addition, the statistical map showed that several brain regions have a nominally significant difference in FA between WT and Cyfip1 +/ − brains (Fig. 2c ).

The annual mean intensity of high temperature during 1961–2005 shows an increasing trend of 0.07 °C/10a.

A clear trend is that increasing the steric hindrance around the amide moiety elongated the N–S bond, which correlates to the performance of these reagents.

Indeed, when assessing the statistical significance of the gene level findings in each group, there are very few genes that are significant in one group that just missed significance cutoff in the other group (Supplementary Figure 2 ).

All of our interactors displayed a distribution of molecular masses that was comparable with the yeast proteome, and only a slight trend towards larger molecular masses (>100 kDa) was observed for the heat-shock interactors compared with the non-heat shock interactors (Supplementary Fig. 8a ).