Barely Significant

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Compared to the HUA group, 15 metabolites were significantly increased and 9 metabolites were significantly decreased in the anserine intervention groups, with fructose, xylose, threonine D-glucuronide and methionine showing an increasing trend, and glycine and pipecolic acid showing a decreasing trend ( Figure 8 B).
Furthermore, when evaluating the percentage of days of abnormal bowel movements, where a day with normal bowel movements is defined as a day with less than or equal to three bowel movements per day with normal stool consistency (Bristol stool scale 3–5), in the PP population, patients in the placebo group showed a trend toward improvement during treatment but without significant results and an increase in abnormal days at week 16, which was numerically higher when compared to baseline levels ( Figure 5 ).
BCAA levels were negatively associated with vegetables (standardized β = −0.029, p = 0.088; −0.051, p = 0.003; −0.038, p = 0.043 for leucine, isoleucine, and valine, respectively), dairy (−0.037, p = 0.029; −0.063, p < 0.001; −0.041, p = 0.028), and fruit (−0.031, p = 0.084; −0.039, p = 0.030; −0.041, p = 0.034), and a positive trend was observed for meat and meat-derived products, but the associations did not reach statistical significance.