Barely Significant

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approached significancep = 0.0511.0× alpha
After adjustment for multiple comparisons, reported ratings (and thus intensity of symptom) of anxiety approached significance at day 17 (1.0 ± 0.4, p = 0.051) and were significantly lower at the intervention endpoint (1.0 ± 0.3, p = 0.048) as compared to baseline (3.3 ± 1.0).
approaching significancep = 0.0511.0× alphagold
In European populations ( n = 194), the mean ratio was elevated (0.91 ± 2.59) compared to a meta-mean of 0.54, approaching significance in parametric testing ( t -test, p = 0.051), but with strong non-parametric confirmation (Wilcoxon test, p = 7.54 × 10 −6 ; Binomial test, p = 2.14 × 10 −16 ) and small positive effect size (Cohen’s d = 0.14) (see Figure 3 ). 4.
showed a trendp = 0.0511.0× alpha
Plasma Appetite-Related Gut Peptides The LED pdr intervention showed a trend towards a decrease plasma GLP-1 (Week, p = 0.051) ( Table 4 ), without a significant difference between dietary groups (Protein×Week, p = 0.176; CHO×Week, p = 0.675; Protein×CHO×Week, p = 0.600) ( Supplementary Table S1 ).
borderline significancep = 0.0511.0× alpha
When adjusted, 3MS scores did not show a significant association with serum calcium, intact PTH, fetuin-A, T50, the use of cinacalcet, or the use of VDRAs, although the association between 3MS and the use of phosphate binders was at a borderline significance ( p = 0.051).
showed a trendp = 0.0511.0× alpha
FGF21 showed a trend ( p = 0.051) in overall change in participants following the LCHF diet after decreasing from a median (IQR) of 148.16 (203.49) to 99.4 (92.43) pg/mL at week 4 and increasing again to 167.38 (152.08) pg/mL at week 8, with post-hoc analysis reporting a trend ( p = 0.069) between baseline and week 4, whereas no change was observed in HCLF.
In addition, pre-menopausal women with obesity showed a significantly higher chance to have an intermediate chronotype (OR = 2.21, 95% CI 1.28–3.83; p = 0.004), whereas post-menopausal women with obesity showed a trend to have a higher morning chronotype (OR = 1.42, 95% CI 0.98–2.06; p = 0.051), although this did not reach statistical significance.