Barely Significant

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Where comorbidity groupings were associated with dramatic FA changes, the tensor-based-registration method did not necessarily translate into higher overall t-statistics than when using FA-based registration [32] , but there were noticeable reductions in significance for comparisons which had yielded borderline significance with the FA-based method (e.g. thalamic lactate/N-acetylaspartate, white matter appearance on conventional MR imaging, discharge neurology).