Barely Significant

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showed a trendP<0.0010.0× alpha
Subgroup analysis showed a trend that reduced PTEN levels were associated with the following factors: depth of invasion (12 studies, 1599 patients; OR = 2.604, 95% CI = 1.554–4.366, P<0.001); lymph node metastasis (18 studies, 2258 patients; OR = 2.484, 95% CI = 1.836–3.360, P<0.001); distant metastasis (9 studies, 1393 patients;
highly significantP<0.0010.0× alphaqualifiedgold
Food Plant Preference 24 h after LCA Damage Determination of food plant preferences revealed a highly significant response that strongly depended on the different treatments applied ( Fig. 1B ; univariate ANOVA: F 4, 103 = 10.065, P<0.001), while colony identity did not affect the model (‘ant colony’ as random factor, univariate ANOVA: F 2, 103 = 0.315, P>0.05).
highly significantP<0.0010.0× alphaqualifiedgold
In concordance with the pattern of increasing genetic distance with increasing geographic distance, Mantel tests revealed highly significant isolation by distance in P . filiformis (P<0.001; S1 Fig ) Correspondingly, the neighbor-joining tree of pairwise genetic distance generally grouped populations according to geography ( Fig 2 ), with populations in the four main geographical areas grouping separately, with each group separated by long branches.
highly significantp-value of <0.0010.0× alphaqualifiedgold
Tumor focality was a strong predictor of survival, as patients with unifocal tumors had a median survival of 17 months (95% CI: 15.111–18.889), while those with multifocal tumors had a median survival of only 6 months (95% CI: 2.801–9.199), with a highly significant p-value of <0.001.
a strong trendP<0.0010.0× alphagold
Using our validated histological scoring system, we were able to detect significantly more villous distortion and total inflammation in TNF i∆ARE/i∆ARE → SCID mice compared to wt → SCID mice, and a strong trend towards more chronic inflammation as well (villous distortion index: 4.00 ± 0.00 vs. 2.00 ± 0.00, P<0.001; chronic inflammatory index: 4.5 ± 1.05 vs. 0.75 ± 0.75, P=0.06; total inflammatory score: 9.25 ± 1.19 vs. 3.25 ± 1.25, P<0.05).
highly significantp < 0.0010.0× alphaqualifiedgold
For boys: Likelihood ratio test comparison between the full model (including age and direct BIS-BAS orientation score) and null model was highly significant ( Χ 2 (21) = 11.22, p < 0.001), with a main effect for the direct BIS-BAS orientation score (estimate ± SE = 0.22 ± 0.06, z = 3.28, p = .001), suggesting that BAS-oriented boys took ~80% of others’ resources.