Excerpts

A highly significant correlation has been established between the automated analysis and the in vivo micro-CT analysis which, in addition with Ashcroft scoring, contributes to validate automated analysis as an end-point measure for quantifying the severity of BLM-induced pulmonary fibrotic alterations in mice.

In particular, the lists of highly significant GO groups presented in Table 1 contained the same GO groups when excluding the designated sample.

Considering deep relationships between the clades, only clades 7–11 were grouped with quite significant support.

No correlation approached significance (-.06 > r s < .12, p s >.24).

Comparisons between instructed mind-wandering periods across groups also showed a trend towards increased high gamma power over parieto-occipital electrodes in the meditator groups.

QQ plots of observed vs expected log-rank p-values for LUAD patients ( Fig 5A ) indicate a strong trend of more significant p-values than those expected by chance.

S2 Table PPIs with nominally significant log-rank p-values for LUAD patient survival PPI and KS.

We also found a significant trend towards higher severity of emphysema in those with lower CD4/CD8 ratios ( Fig 1 ).

Significant p-values marked in bold (p < 0.05); highly significant p-values (< 0.0001) marked with **.

There were 20 highly significant Quantitative Trait SSRs (QTSs) detected by mixed linear model approach analyzing a full genetic model with genetic effects of additive, dominance, epistasis and their environment interaction.

The only effect that approached significance was Element 5, suggesting that liberals became more aware of uncertainties in climate science after reading the medical analogy.

In all three models, and in both men and women, there were significantly increased odds of drinking more than the daily recommended limit (>4/3 units) in the 7+ calls group, although this was only of borderline significance in the fully-adjusted model for men.

A trend was also observed for these participants to be more likely to report strict dieting and overvaluation of weight/shape, however these estimates approached but did not reach significance.

Except for ETM values, highly significant correlations were found between most of the MRI methods investigated.

Stratification of OS by treatment center revealed a highly significant increase in OS for patients who underwent surgery in expert centers according to CPGs.

Prediabetes-associated SNPs and microalbuminuria In Mendelian randomization, which is a form of instrumental variable regression analysis, the instrumental variable-estimated size of the effect of prediabetes on log-UACR was highly significant and consistent for all outcomes (β = 0.015 [95% confidence interval (CI) 0.014–0.016] for fasting plasma glucose, 0.065 [0.011–0.012] for postprandial glucose, and 0.216 [0.198–0.234] for HbA1c; Table 4 ).

An interesting trend is emerging from the characterization of multimodular C . perfringens CAZymes, where the enzymatic activity of the catalytic module rarely matches the binding preferences of the resident CBM32 modules [ 14 , 21 , 25 , 51 ].

Interestingly, a clear trend towards reduced Th17 levels in draining lymph nodes of mice receiving either early single or combination treatment was present, despite the late time point of analysis (day 35).

However, we found a close to significance trend for trials where the first author was a psychologist/social scientist to report more favorable outcomes for pharmacotherapy than studies where the first author was a psychiatrist/MD (b = -0.25, 95% CI -.51 to 0.01, p = 0.06).

OVX caused a marked increase of cathepsin K compared with SHAM; SW and RAL alone showed a trend of enzyme reduction that reached significance when combined ( Fig 5A ).

RAL treatment of OVX rats showed a decreasing trend in body weight gain compared to OVX group.

Hence, in the obtained final model, the season-treatment-physiological stage interaction is very close to significance, whereas the apiary-treatment-physiological stage interaction is clearly significant, as are the physiological stage-apiary and the treatment-apiary interactions, and the apiary factor.

According to the present investigation, the occurrence of drug resistance mutations both in viruses from individuals receiving ART and in transmitted viruses to ART-naïve individuals is increasing at a global level[ 21 ],[ 22 ] It is noteworthy that the prevalence of TDR is low in resource-limited settings, however it maybe show an increasing trend in recent years.

SM also showed a trend towards modifying CD4+ T cell memory subsets from HIV+ subjects.

The contour of normalized characteristic admittance shown in Fig 4B presents a clear trend approaching 1, as the network length and the electrode dimension increase.