Excerpts

EBV is accepted as a major contributor to Hodgkin lymphoma and there are striking and highly significant correlations between the incidence of Hodgkin lymphoma and breast cancer which suggests that EBV may also contribute to some breast cancers [16] .

In addition, it also demonstrated a possible trend for males to have a higher malignancy risk compared to females.

We find that all coefficients are highly significant, meaning that a model that would only consider diversity or ubiquity, or both of them without an interaction term, would not be as accurate.

When morcellated uterine tumors are unexpectedly found to be leiomyosarcomas or tumors with atypical features (atypical leiomyoma, smooth muscle tumor of uncertain malignant potential), there may be significant clinical consequences.

The NP 311–325 CD4 T cell response in IL-7Rα 449F cells also showed a trend towards impairment, but this was not a significant difference ( Figure S4 ), perhaps due to the lack of a robust response in WT CD4 T cells in these chimeric mice.

The levels of tPSA over the years didn't show a significant trend, however, because of the significant decrease of percentage of patients with tPSA>20 ng/mL, we can still conclude that PSA screening had benefits over the years.

When data were cumulated for patients with localized melanoma or disseminated disease (e.g., absence or presence of metastases), there was a clear trend whereby percentages of total γδ T cells and their Vδ1 and Vδ2 subsets declined in patients with advanced disease, but again only differences in percentages of Vδ2 T cells were significantly different.

Specifically, whereas events 27 and 39 yielded only marginally significant evidence that the tree topologies obtained using the recombinant fragments fitted the data significantly better than the tree topology determined from the 720,090 nt long original alignment ( i.e., yielded test p-values between 0.05 and 0.01), events 7 and 10 only yielded statistically significant p-values for the AU test, events 8, 13, 16, 28, 33, 34, and 74 only yielded significant p-values for the AU and WSH tests and none of these yielded significant p-values with the SH test.

While in this study, the use of serum resulted in a slightly higher test performance of THBD-M and the multiplex compared to plasma, this difference was of borderline significance.

However, this association remained only marginally significant after adjusting for multiple comparisons (FDR = 0.056).

Emotional Abuse Recently, family-environmental factors such as abnormal intra-familial relationships, lack of emotional warmth towards the child, child maltreatment (physical/emotional), frequent arguments and fights between adults in the family, ambiguous communication patterns, parental separation/divorce and isolated family units, showed a trend towards an increasing risk for having a child with ADHD-related disorders, as reported previously in numerous studies.

In the present study, group interactions and second-order conditioning were present in both experiments, with the conditioned inhibition effect in Experiment 2 approaching significance.

All correlations were highly significant and showed a decrease in pH, oxygen and an increase in conductivity with decreasing temperature values ( Table 1 ).

Female mice also had disturbed glucose metabolism: the mice showed a trend toward elevated fasting glucose at 14 weeks, and a statistically significant elevation at 26 weeks of age.

GBP-1, which is expressed in response to interferon-γ, is considered to be an activation marker during inflammatory diseases, and up-regulation of GBP-1 in humans has been associated with a highly significant, increased five-year survival rate in colorectal cancer patients.

We found that carps displayed a statistically highly significant spontaneous preference to align their bodies along the North-South axis.

Since melatonin secretion is affected by day length, differences in melatonin secretion because of variations in day length may be significant factors in the geographical gradient in height.

The world distribution of age at menarche shows a decreasing trend as the geographical latitude approaches approximately 25–30 degrees and then increases again toward 0 degrees (near the equator) [44] .

While maternal grandmothers were more fecund than paternal grandmothers for homosexuals (t = 1.944 p = 0.052), with a marginal significance, there was no difference in grandmother fecundity in the heterosexual sample.

Lower levels of apelin compared to baseline persisted after six months from surgery and were not related to the highly significant reduction in BMI observed.

4 ) – a highly significant point and, even though the in vitro model has its limitations in fully mimicking the cell destructive process after transplantation, the data clearly demonstrate that pegylated, nanoparticle decorated islets have superior survival advantages over naked islets.

The combination phylogeny for birds showed marginal significance between behaviour and curvature, but this result was diminished by the lack of explained data.

Retinal Vessel Calibre and Association with HIV and Age In unadjusted analyses, there was a significant trend of narrower arteriolar diameters (P-trend = 0.002), and venular diameters (P-trend = 0.001) with increasing age in the HIV-infected group, also evident when stratified by gender (data not shown).

When performing an interaction contrast between diagnosis and age group, we observed highly significant clusters in the bilateral inferior and superior parietal cortex, the orbitofrontal cortex, the paracentral lobule and the lingual cortex.

The mortality data was not case-mix adjusted and there is likely to be significant variation here across England.