Furthermore, when controlling for metastasis at the time of diagnosis, clustering using the 22-miRNA profile (reduced to 18 miRNAs due to mapping attrition) showed a trend toward significance (median RFS 8 vs 27 months, and 64 vs 105 months for metastatic and non-metastatic subgroups, respectively, stratified log rank p = 0.11).
In the absence of tissue composition correction, our raw data showed a trend towards increased GABA+/water ( t (1,36) = −1.64, P = 0.11) and GABA+/Creatine ( t (1,36) = −2.01, P = 0.05) in older adults relative to younger adults.
No other significant correlations were observed, though abnormal_sum demonstrated a negative trend with SIR_3 year ( p = 0.111, marginal significance).
Under multivariate analysis, patients with poor survival spectra showed a trend of correlation with increased risk of death compared to patients with non-poor survival spectra (Cox regression model, HR [95% CI] = 2.48 (0.81–7.57), P = 0.111, Table 3 ).
Despite a strong trend towards lower levels in surviving patients became apparent, the difference again did not reach statistical significance (p = 0.113; Fig. 4B ).
In the positive CK7 prediction group, OS was also poorer than negative prediction group (P = 0.052), which was very close to being statistically significant and RFS was not good enough (P = 0.113) (Fig. 9 ).
However loads peaked 2 dpi at significantly higher levels in male nasal swabs compared with female (mean log 10 7.16 vs 6.44 gRNA IU/mL, respectively (Mann–Whitney rank sum test, p = 0.013), though only weakly significant 4dpi (one-tailed t-test, p = 0.114).
For female respondents, age ( p = 0.016***) and education level ( p = 0.047***) emerged as the strongest predictors, with floor level showing marginal significance ( p = 0.115*), suggesting women’s safety awareness is more strongly influenced by socio-demographic factors and environmental context.
At 10 weeks HFD mice already showed a trend towards reduced burying activity (21 ± 7; control: 29 ± 7, p = 0.1151), and after 30 weeks of diet, the HFD mice demonstrated significantly reduced activity compared to age-matched controls (10 ± 7; control: 20 ± 9; p = 0.0004).
For TA, the directional dependency approached significance, with p = 0.116 at 50 kPa and p = 0.067 at 75 kPa.
Almost significant ( p = 0.11741) was the frequency of isolation of C. tropicalis in the Surgery department (panel a).
This effect was attenuated by the presence of minor alleles rs35643203 and rs12201140, which showed a clear trend towards low VIP level association (p = 0.118 and p = 0.049, respectively).
In large trajectories, NK cells showed a trend migrated faster at 1.94 ± 0.2 μm/min on pTNF-treated PAECs versus 1.5 ± 0.23 μm/min on control PAECs, P = 0.1184 (Fig. 4 F, right).
For those taxonomic groups found consistently within both the infauna and epifauna, namely the amphipods and isopods (n = 22 samples), the difference in terms of δ 13 C, when accounting for site-specific variability as a random intercept in the LMM model, was marginally non-significant (infauna respective to epifauna: C = −1.7 ± 1.0 SE; t = −1.6; p = 0.12).
A weak trend for shorter median TTT (by 45 days; p = 0.12) and attained age (by 36 days; p = 0.12) was observed for animals with tumors exhibiting LOH (Supplementary Fig.
Fatigue showed a trend toward increased risk in the eptinezumab group (RR: 1.92, 95% CI 0.84–4.39, P = 0.12, I 2 = 41%), though it was not statistically significant.
Although HCT-ALB independently predicts mortality, it showed a nonsignificant trend toward superior discrimination compared to HCT alone ( P = 0.12), it was significantly inferior to ALB ( P < 0.001).
In contrast, in primary PCa, the Wnt pathway showed a trend towards increased activity (p = 0.12), and median FOXO activity was only slightly lower than in healthy tissue (p = 0.12) indicating that PI3K pathway activity was restricted to a subgroup of PCa.
All S6 scores significantly detached from baseline as demonstrated by the results of the one-sample t-tests where both GA and MD returned significant findings [GA: AOT t (35) = − 7.20, p < 0.001; CTRL t (35) = − 4.96, p < 0.001], [MD: AOT t (35) = − 3.00, p = 0.005; CTRL t (35) = − 3.91, p < 0.001] while FL exhibited only a trend toward significance but selectively for the AOT group [AOT t (35) = − 1.61, p = 0.12; CTRL t (35) = − 1.10, p = 0.28].
One of the central hub genes KIF23 showed a trend toward association with poor survival (Hazard ratio = 2.2; p-value = 0.12), though this did not reach statistical significance, likely due to the limited sample size of CHOL in TCGA.
Going back to our choice of the parsimonious model, even though the one we arrived at did not significantly differ with the MMP-Model, there was a trend toward marginal significance ( p = 0.121), and thus one might wonder whether our results would change had we adopted the more complex model.
Accordingly, a two-way repeated measure ANOVA showed a slight trend in favour of an easier prediction task on A-V intercept ( β diff = - 0.011 ∈ [ - 0.07 , 0.003 ] 95 % C I , p = 0.122 ).
When ant 48 was retained in the dataset the proportion of ommatidia on the left eye was not quite significant as a fixed factor explaining directional choice taken (p = 0.123).
Additionally, a positive trend was identified between miR-432-5p and non-perseverative errors in the WCST ( r = 0.212, p = 0.124).
Patients with TBI showed a trend towards elevated PER2 ( OR = 3.00 [0.84–9.33], P = 0.125) , but not towards delirium occurrence ( P = 0.556).