114 SNPs were found to be nominally significant on chromosome 9.
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676 patients completed the step 1 analysis, which showed a trend of NMSs worsening but not significant until the disease duration longer than 4–6 years.
Only motor function (UPDRS Part III 19 to 27.5, p = 0.012) and sexual dysfunction (NMSS domain 8 score 2.24 to 0, p = 0.016) showed borderline significant differences.
The use of natural extracts in cancer prevention and treatment has been an increasing trend as the numerous data in the traditional medicine suggest that these natural extracts possess anti-proliferative activities on different cancer types 25 – 27 .
During the study priod, meropenem consumption intensity showed an increasing trend with time from 2015 to 2019.
Related to the number of samples measured, although no statistical differences were found among experimental groups when SUV for [ 18 F]FDG is measured in the intestine, there is an interesting trend showing an attenuation from the LPS effects carried out by peptide VSAK (Fig. 1 C), results that agree with the PET images shown earlier.
3 is statistically highly significant and extends more than one order of magnitude in Ξ and over four orders of magnitude in mortality.
The ammonium concentration of soil amended with BSFFF and SAFI followed a decreasing trend throughout experiments.
an overall trendgold
During the follow-up periods, entire PD patients showed an overall trend of decrease in CSF α-syn and Aβ 1-42 , whereas serum NfL were increased.
Lower CSF α-syn and t-tau levels showed a trend of association with higher MDS-UPDRS III total scores at baseline, however, generalized linear models did not reach statistical significance (CSF α-syn, β = − 7.15, SE 3.85, p = 0.065; CSF t-tau, β = − 0.62, SE 0.34, p = 0.069). 311 PD patients showed MoCA total scores greater than 25 at baseline and were classified as PDNC.
NC 6 approached significance (Table 1 ; mean = 0.22, sem = 0.13), indicating that these conditions showed a small bias for being judged as moving.
Habitat conditions quantified by tree and shrub cover did not significantly influence abundances, species richness and community composition of the transects, except for a marginally significant positive correlation of tree cover and species richness.
In the meantime, coulombic efficiency (CE) showed a decreasing trend and dropped by ~ 3% for the fructose/PEG-fed electrochemical reactors and by 10% for the EtOH reactors.
However, the effect size was notably small and only marginally significant when considering young and healthy subjects (Cohen’s d = 0.13).
There was no significant evidence for unequal distributions of social value orientations among the four groups, Pearson’s Chi-squared test, χ 2 (9,99) = 16.87, p = 0.051, suggesting that baseline differences in prosociality should not explain group differences, even though the results almost reached significance.
It was reported that global coal consumption had shown a decreasing trend in recent years.
a slight trendgold
HSQC NMR of the recovered lignins suggest a slight trend towards greater ether cleavage with increasing solids loading (Figure ESI-7 a).
It would lead to an apparent trend for increased ether cleavage without more pronounced condensation at higher loadings, while increasing pulp yield and decreasing lignin recovery.
a negative trendgold
Slope was the 3rd ranked variable at Cape Crozier (ΔR 2 = 11.1%, also a negative trend) and aspect was the 4th (ΔR 2 = 9.4%).
a clear trendgold
The effect of CPA concentration was also significant for MII oocytes exposed to Me 2 SO (p = 0.014), but in this case, the CPA permeability did not exhibit a clear trend: the lowest permeability was 0.38 μm/s at 0.68 mol/L and the highest was 0.68 μm/s at 1.55 mol/L.
It was found that mKl was not expressed in the skin or the pulmonary tissue of NMR, while a highly significant expression of mKl was demonstrated in the liver of NMR.
At 4 dS m −1 , SA at 100 proved highly significant as it increased proline content by 71%, followed by improvement of 40% at 50 or 150 ppm.
a possible trendgold
Its distribution shift may imply a possible trend of polarisation in functions: both acquisitive and conservative species occur simultaneously.
In the GSEC, the scale and efficiency of the Changsha-Zhutan, the city groups on the west coast of the Taiwan Strait, and the Beibu Gulf city groups show an increasing trend, indicating existing factors of the allocation structure has formed a certain scale effect within the three urban agglomerations, but the pure technical efficiency of the urban agglomerations on the west coast of the Straits and the urban agglomerations outside the northern part of the Straits is showing a downward trend.
Yet, the variance among populations within groups was highly significant, reflecting the complexity of other factors that account for the pattern of genetic differentiation between Tunisian population 37 , 43 , 44 .