Excerpts

Similarly, the interaction between the lipid phase concentration and homogenization time (X 1 X 3 ) showed a slightly significant negative effect on SE% ( p = 0.0066) ( Fig. 1 (a-III)).

Not every ‘poor’ tumour relapses and not every ‘good’ tumour remains disease free, but an overall trend is seen in the population and the 3-year RFS based on CT predicted T-stage criteria was 71 vs 43% ( P <0.0066).

All tests against chance level (37.5%) were highly significant: 3-year-olds binomial two-tailed p = 0.0066, 4-year-olds p = 0.022, 5-year-olds p = 0.001.

In the Static Functional Index, the Toe Spread Factor (TSF), which is the measurement from toes 1 to 5, is the most significant ( p < 0.0001), followed by the intermediary toe spread (ITS) factor (toes 2 to 4), which has near marginal significance ( p = 0.0066), and it excludes the print length (PL) factor, due to its high variability and statistical insignificance ( p = 0.3362).

Using a time-to-failure Cox mixed effects model, the authors found that FFR was a highly significant continuous predictor for events (HR <0.01; p=0.0067), while CFR was no significant predictor (HR 0.74; p=0.44).

We also found marginally significant heritability for G × E interaction in TDI ( h G×E 2 = 0.42%, P = 6.70 × 10 −3 calculated by LDSC; h G×E 2 = 0.23%, P = 1.16 × 10 −2 calculated by LDAK-SumHer).

All of the top 20 differentially regulated pathways showed highly significant enrichment (p=0.0067) and were immune-related, including leukocyte activation, innate immune response, and cytokine production ( Figure 6F ).

The association for CORE_MATRISOME was found to be marginally significant (p = 0.0067 under SKAT) ( Figure 3 B).

Similarly, when examining the yearly occurrence of OPSCC in males, we found a significant trend for both p16 positive cases (Spearman r = 0.9286, p = 0.0067; linear regression R 2 = 0.8675, p = 0.0023) and p16 negative cases (Spearman r = 0.8469, p = 0.0238; linear regression R 2 = 0.7591, p = 0.01) (Fig. 1 C).

After one intake cycle, SYN‐53 already showed a trend towards greater efficacy over placebo, which became significant after two cycles (ΔTSS MAX : −3.44 ± 0.42 vs. −1.87 ± 0.37; p = 0.0067), with 38% vs. 24% symptom relief.

The differences between genotypes was highly significant, Chi-square test χ 2 (2, 358 ) = 10.0, p value = 0.0067.

The difference between the two genes in I TE is highly significant based on a paired-sample t -test (t = 4.4527, DF = 5, P = 0.0067, two-tailed test).

Finally, we found a near-significant effect of antipsychotic drug use on mean caudate volume (β=0.016; P -value=6.71 × 10 −3 ), implying that caudate volume of depressed patients was greater as the percentage of patients taking antipsychotic drugs was higher ( Supplementary Figure S7 ).

At present, the OS data on the first‐line use of osimertinib compared to geifinib or erlotinib is immature, but osimertinib has displayed a positive trend (HR 0.63, 95% CI 0.45–0.88%; p = 0.0068). 44 The efficacy of osimertinib was better than that of first‐generation EGFR‐TKIs in a first‐line setting, this may due to the lower early resistance rate of osimertinib, which delays the emergence of acquired resistance. 34 , 45 , 46 In addition, in contra

The mean size of the growth fraction, as determined by MIB-1 labelling index (MIB-1 LI) at first biopsy, showed a highly significant difference in the disease-free survival between the two groups ( P =0.0068).

5G-I , the difference in RFS time between the patients with and without venous invasion was markedly significant in the high-risk group (P=0.0068), but was not significant in the low-risk group (P-value=0.1244).

There was a negative trend in APC for meningitis (APC = ‒3.42; 95% CI ‒5.65, 1.13; p = 0.0068) between 2010 and 2024.

By contrast, in another previous study conducted by Goodarzi and Van Herle on hCG and hyperthyroxinaemia in 17 male patients with germ cell tumours aged 16–50 years, a highly significant correlation of serum β-hCG levels between 200,000 and 3.06 million U/L with total T4 was observed ( r = 0.76; P = 0.0068) ( 25 ).

Of the K14CreER TM+/- /Atg7 f/f mice treated with DMBA and 4-OH Tam, 40% (six out of 15) developed SCCA compared to 0% (0 out of 16) of K14CreER TM+/- /Atg7 f/f mice treated with DMBA only, trending towards significance (Fisher's exact test P = 0.0068).

The frequency of allele Pan I A revealed a negative trend towards the south (τ = 0.23, P = 0.0068, Fig. 4 ).

The overall survival (OS) data was only 25% mature at time of analysis and was not statistically significant however did show a positive trend (HR 0.63, 0.45–0.88; p = 0.0068).

Although methylation at CpG site cg19859270 of GPR15 failed to reach significance, the gene expression signal for GPR15 correlated negatively with RTE% ( P = 0.0068, r 2 = 0.0803) ( Figure 6H ) and was elevated in smokers ( Figure 6I ).

There was a highly significant increase in α for atomoxetine compared to placebo when collapsing across voxels as well as across Fixation and Task-counting ( p = 0.0068, t = 2.93; paired t test, Fig 4B and 4C ).

The median survivals of the control group and the 2 groups treated with 100 and 300 μg/kg of SGN CD70A were 20 days, 28 days, and 57 days, respectively; and the survival difference between the SGN-CD70A 300 and the control group was highly significant, with P = .0069 ( Figure 4B ).

AB1 Reduced the Gene Expressions of BRCA1 , BRCA2 , and p53 in MCF10A Cells AB1 resulted in a highly significant reduction in the gene expression levels of BRCA1 (0.25/ p = 0.0069) by 75%, BRCA2 (0.061/ p = 0.0016) by 99.939%, and p53 (0.055/ p = 0.0019) by 99.945% compared to the control of each gene as represented in Figure 9 A. 2.6.2.