Barely Significant

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highly significantp = 0.0080.2× alphaqualifiedgold
When partitioned into low (n = 16) and high (n = 17) reactive groups, the high reactive group showed a highly significant decrease in SBR during the IT period compared to baseline (11.1 ± 1.09 blinks per min to 6.2 ± 0.95 blinks per min, t 1,30 = − 2.9, p = 0.008) and a significant increase in SBR from baseline during the CT period (11.1 ± 1.09 blinks per min to 15.6 ± 1.71 blinks per min, t 1,30 = 2.7, p = 0.012).
highly significantp = 0.0080.2× alphaqualifiedgold
In detail, the intensity of tumoral HLA-I HC/β 2 -m surface expression correlated highly significant positively with the density of intra-tumoral CD8 + T cells ( p = 0.008 resp. 0.003), but negatively with the number of CD8 + T cells adjacent to FoxP3 + cells within a radius of 30 μm ( p = 0.009 resp. 0.007) ( Table 5 ).
a significant trendp = 0.0080.2× alphagold
In the higher quartiles of blood cadmium, there were significantly higher proportions of females, those with high school or equivalent education, those with lower household incomes, current smokers, and stroke patients. Blood cadmium concentration and stroke As shown in Table 2 , in the most adjusted model, participants in quartiles 2, 3, and 4 had an OR for stroke compared with the lowest reference group for blood cadmium in the total population, with OR of 1.32 (95% CI 0.55–3.14), 1.65 (95% CI 0.71–3.83), and 2.67 (95% CI 1.10–6.49), respectively, with a significant trend (p = 0.008).
highly significantp < 0.0080.2× alphaqualifiedgold
Interestingly, despite the fact that the actual target of selection is not known, the clinal frequency change is highly significant ( p < 0.008) based on Student’s t test for 10,000 random sets of SNPs generated by jackknifing 21 SNPs out of the 197 SNPs segregating in the region of interest (3R: 4,239,638-4,271,390, Additional file 1 : Figure S15).