Excerpts

For the plastic bag-samples, a highly significant difference between the reference material and the two obtained samples (plastic bag-metal and plastic bag-no metal) was observed (1-way ANOVA, F = 12.9, p = 4.5 × 10 −5 ), while the means of the two plastic samples showed no significant difference (post-ANOVA Tukey-test, p adjusted = 0.11).

We found that the expression of IL2RG, used by all common gamma chain cytokines, exhibited a highly significant upregulation pattern in SIV compared to control ( p = 0.000045), and in SIV/Meth compared to SIV ( p = 0.0001).

There was thus a highly significant association between flight performance in the cage and outside (Fishers exact test: two-tailed P = 0.0000452).

Apart from immunity and defense ( P = 5.84×10 −11 ), other highly significant biological processes highlighted include chemokine and chemokine-mediated signaling ( P = 4.53×10 −5 Table 3 ).

Variants at PHLPP1 were also nominally significant in the independent meta‐analysis of African individuals that included WGS data ( p = 4.56 × 10 ‐5 ).

The results are shown in Figure 2 , with the probability of belonging to the Dent and the Flint groups for each parental line (Figure 2 A) and the highly significant correlation ( P value = 4.6 × 10 -5 ) observed between the GWRR in a population and the average 'flintness' of its parents (Figure 2 B).

In this database, only one SNP (rs331142) in the ROBO1 gene showed a trend for association to ROBO1 expression ( p = 4.6 × 10 −5 ), but it did not reach genome-wide statistical significance (Tran et al. 2014 ).

Linear regression with parameters as predictors was highly significant, but accounted for a far smaller amount of variance than the synthetic data (adjusted r 2 = 0.36, p = 4.6E-5).

The P-value is highly significant when corrected for multiplicity (207 sites, Bonferroni corrected P-value = 4.6e-5).

Crude rates in PMRT were 22.5% for prepectoral reconstruction (25/111), 62.9% for submuscular DTI (22/35), and 39.1% for expanders (9/23), with a highly significant overall difference (global χ 2 p = 4.61 × 10− 5 ).

Further examination of the tumor tissue sections after anti-PD-1 therapy revealed the co-localization of mast cells and FOXP3 + Treg cells, which was consistently observed and highly significant ( p = 0.000047) when compared to control-treated tumors (Fig. 4e ) and this may be associated with downmodulation of HLA class I on tumor cells (Fig. 3g, h, f ).

The difference in this increase in nuclear enrichment upon exercise between HITT and TRAD was 1.89 and highly significant ( P = 4.7 × 10 −5 ; Fig. 6 C , SI Appendix, Fig.

These analyses demonstrated for example a clearly significant enrichment for ESRRA binding motifs (∼2-fold, P = 4.8E-5) ( Supplementary Data Sheet 1 ), suggesting that the transactivation activity of ESRRA may depend on the DNA methylation status of its binding motif.

50 synonymous), and highly significant G -test results ( G = 15.20, P = 0.000048).

Using a logistic regression on the model ln(w ij /(1−w ij )) = a+b ln(P i P j ) , we observe a highly significant negative correlation between confirmation probability w ij and log-transformed popularities of the interaction partners ( a = −1.41±0.04; b = −0.020±0.005, p = 4.8*10 −5 ; N = 62,864 statements).

Migraine showed modestly significant genetic correlations (Bonferroni-corrected P < 4.8 × 10 − 5 ) with chronic pain duration and susceptibility ( r g > |0.5 | ).

By that time, decreases in cell counts were still highly significant ( P = 0.000049 and P = 0.00006 for CD3 + and CD3 + CD4 + , respectively).

There was a highly significant effect of regions (linear mixed model, P = 0.000049).

As expected, we observe stronger average absolute correlation in the ISO-treated cohort ( R = 0.174 vs 0.111), and that while the control cohort’s correlations of the adrenergic signalling pathways with Serpina3n were not significantly higher than expected ( p = 0.728), the correlation of Serpina3n expression with the ISO cohort was highly significant ( p = 4.9 × 10 −5 ).

Meta-analysis of the 2 cohorts yielded highly significant evidence of association with JIA (OR 0.76 [95% CI 0.62–0.88], P = 4.9 × 10 −5 ).

Myc knock-down had a highly significant effect on the extent of glial dedifferention (one-way ANOVA, F (3,13)=18.99, p =4.94×10 −5 ).

Of note, eleven of the 16 novel GWS loci exhibited consistent genome-wide marginal significance ( P < 5 × 10 −5 ) between ADHD and MDD.

This revealed a highly significant correlation (r = 0.80, p<0.00005; Appendix 2—figure 1D ).

The results presented in Table 3 showed a highly significant ( p value = 0.00005, detection limit of the method being approximately 1 log CFU, CI-95%, 1.85, 2.77) log reduction (2.31) in microbial load after wiping the meat surface with the developed DW (count before treatment—5.48 log CFU/cm 2 ; after treatment—3.17 CFU/cm 2 ).

The differences are highly significant for every one of the possible comparisons involving two out of the three groups ( P < 0.00005 in every case).