Moreover, in inflamed biopsies, a positive trend was detected (Pearson’s test p = 0.058).
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Microglial EP2 expression (MI) was higher in the lesion ( p = 0.029) and showed a positive trend in the peri-lesional tissue ( p = 0.058) compared to NNC (Fig. 4 e).
We calculated the average latitude of recorded nests for each year ( Fig 3A ), which shows a positive trend over time (r Pearson = 0.86, p = 0.058).
When focusing on the dominant host, red oak ( Quercus rubra ; n = 32), no significant relationship was detected below 1 m ( ρ = 0.096, p = 0.600), but a positive trend was observed above 1 m ( ρ = 0.339, p = 0.058), suggesting a tendency for greater oviposition on taller portions of larger individuals ( Figure 3 ).
Regarding inflammation‐related genes, IL‐6 expression was significantly lower in the FEHC group compared to the FCD group ( p = 0.0363; Figure 7A ), while IGF‐1 expression showed a positive trend in the FEHC group compared to the FCD group ( p = 0.0585; Figure 7F ).
Additionally, a positive association between miR-1-3p and TNF was identified (p = 0.031, β = 2.193), with a positive trend observed for IL-17 (p = 0.059, β = 1.932) ( Fig. 6 ). 3.7 Functional enrichment analysis To identify miRNA-target interactions and the pathways affected by the validated miRNAs, we employed the MIENTURNET tool [ 30 ].
The lumen stenosis rate showed a positive trend but did not reach statistical significance (r = 0.510, p = 0.059), and MLA was significantly negatively correlated with RC (r = -0.767, p < 0.001).
Although not statistically significant, a positive trend between the change in MVPA and the change in general health was observed (ρ = 0.19, p = 0.059).
2a ; Model 2 A: Estimate = 0.762, SE = 0.146, p < 0.001; Table 2 ) and the model with FFC as random slope revealed a positive trend for the influence of the frequency of female coalitions (Model 2B: Estimate= 0.723, SE = 0.318, p = 0.059).
Regression analysis In univariate analysis, the RRI was positively correlated with age ( r = 0.36, P = 0.013), SBP ( r = 0.32, P = 0.011), PP ( r = 0.31, P = 0.017) and media-to-lumen ratio ( r = 0.39, P = 0.003); RRI and the inhibitory response of L-NAME to ACh vasodilation showed a positive trend ( r = 0.25, P = 0.059).
There was no significant association between the whole‐blood IGS and LINE‐1 transcription expression (Figure 1D ), despite a positive trend ( P = 0.06) between the IGS and circulating IFN‐α (data not shown).
The correlation between SKP2 protein levels and IC50 values showed a positive trend (Pearson r = 0.7767), with a p-value near significance ( p = 0.06), (Supplemental Fig.
Further subgroup analysis revealed that HbA1c levels ≥6.5% were significantly and positively associated with anterior circulation stenosis ( r =0.13, P =0.03) and showed a positive trend with posterior circulation stenosis ( r =0.13, P =0.06).
33 37 One additional study, 39 a CBSM web-based programme, reported a positive trend in functional well-being (p=0.06) and emotional well-being (p=0.07) on the FACT-G subscale.
The variable VPR showed a positive correlation with SCD ( p = 0.04) and a positive correlation with CAD ( p ≤ 0.01), while also presenting a positive trend with SIW ( p = 0.06).
Pooled effect size analysis demonstrated a RR of 1.11 (95% CI = [1.00, 1.24]), indicating a positive trend favoring the treatment group, but this did not reach conventional statistical significance ( p = 0.06).
For ROCF score, we observed a positive correlation with CSF irisin ( p = 0.001; r = 0.468), and a positive trend near statistical significance for serum irisin ( p = 0.060; r = 0.331) (Figure 2D,H ).
Although the expression of PSMA3-AS1 in relation to the size of the tumor was not statistically significant, a positive trend towards higher PSMA3-AS1 expression in bigger tumors was demonstrated ( p = 0.06), ( Figure 6 ).
Among carriers, there was a positive trend between bacterial density and M.pneumoniae copy number (rho 0.23, p = 0.06, Supplementary Figure S3B ).
However, the correlation between muscle and liver P efficiency showed a positive trend ( p = 0.060).
There also appears to be a positive trend with the tree composition of the genera Eugenia , Podocarpus, Olea , and Washingtonia ( Figure 4 d), but this relationship is not statistically significant ( p = 0.060).
However, there was a positive trend-level correlation between RT difference and M-ratio scores, Spearman’s r = 0.32, p = .06, BF 10 = 1.02 (Fig. 4 B), suggesting that—if anything—lower RT differences, which are indicative of better mentalising, are associated with lower M-ratio.
However, when comparing pathological complete response (TRG1) with all other categories, a positive trend was noted ( p = 0.06), but without statistical significance.
The subgroup analysis suggested that the combination therapy not only provided significant improvement in PFS (HR = 0.60, 95% CI 0.39–0.90; p = 0.01), but also had a positive trend to prolong OS (HR = 0.69, 95% CI: 0.46–1.02; p = 0.06) in patients with brain metastasis (Fig. 4 A, B).
In the overall population, OS was significantly improved in the toripalimab group, with 17 months in the experimental arm vs 11 months in the placebo group (HR = 0.58, 95%CI: 0.43-0.78; P = 0.0004), maintaining a positive trend in PD-L1 CPS ≥ 10 subgroup, though without reaching statistical significance (17.0 months vs 10.9 months, HR = 0.64, 95%CI: 0.40-1.03; P = 0.06)[ 26 ].