“a strong trend”

Analyzing the stromal compartment and thus excluding TLS-associated B cells, this effect was significant in the intratumoral region (p=0.047) and displayed a strong trend in the peritumoral region (p=0.058).

There was a strong trend for a main effect of stimulus type, F (1, 23) = 3.99, MSE = 0.029, p = .058, η 2 p = .148.

Decomposition revealed a strong trend towards a significant Instruction x Waveform interaction in the AP 30 -positive group [F 1,34 = 3.84, p = 0.058, η p 2 = 0.10].

A two-way ANOVA showed a significant effect of time (F(3, 53) = 3.735 p = 0.0165) as well as a strong trend for an effect of bedding (F(1, 53) = 3.743, p = 0.058) to increase Bmal1 expression in LB group.

7 C) in a sex-dependent manner from d3 to d14 (p < 0.01) and a strong trend at d28 (p = 0.058, Fig. 7 C).

At 48 h, the effect of oAβ challenge was more apparent, showing decreased Vps25 levels in all cell types, with a significant decrease in N2a-PRNP cells and a strong trend in PrP KO cells ( p = 0.058) (Fig. 1 D, E). nSMase2 and Rab31 showed similar results at both 6 h and 48 h (Fig. 1 D, F–H).

For DFS, TRα showed a strong trend as an independent factor for recurrence ( Table 4 ; p = 0.058).

However, there was a strong trend toward a reduced ratio of p-AKT (S473) to total AKT ( p = 0.0582) ( Figure 2 B).

However, higher-resolution micro-computed tomography (microCT) measurements of cortical bone in the midshaft of the femur demonstrated that BAY-treated mice had a subtle but significantly greater cortical bone volume fraction ( P = 0.0286; Figure 5B ) as compared with VEH-treated mice, resulting from a strong trend for greater cortical bone volume ( P = 0.0583; Figure 5C ) without an impact on cortical bone tissue volume ( P = 0.2807; Figure 5D ).

S-NT-A animals showed a significant reduction in this measure compared to C-NT mice ( p = 0.0145, Tukey’s test), and there was a strong trend for a decrease in this measure compared to S-NT-R animals ( p = 0.0584).

Interestingly, there was a strong trend toward a similar degree of nSMase2 reduction in sporadic FTLD-TDP-A ( p = 0.0586).

For ambulatory time following five impacts, there was no treatment group or interaction effect however time post-injury showed a strong trend for significance ( F 3.067,54.44 = 2.620, P = 0.0588, Fig. 10 A).

There was a strong trend for an effect of sex [ F (1, 14) = 4.27, p = 0.0589, Figure 4A ].

However, interestingly, we found a strong trend for loss of club cell Creb1 to augment the percentage of cells that were granulocytes in female airways ( p = 0.059, Figure 3H ; Table 3 ).

A strong trend for a genotype x treatment interaction was noted ( p = 0.059) ( Figure 3H ).

For spheroid staining, Donor 2 revealed a significant reduction in BMPR2 expression compared to Donor 3 ( p = 0.007), with a strong trend in reduction in relation to Donor 4 ( p = 0.059) and a diminished though evident trend in comparison to Donor 1 ( p = 0.106).

Between baseline and 1 year, average daily step count and percentage of time in moderate activity intensity significantly decreased (−9.7·10 2 ±2.2·10 3 steps and −1.1 ± 2.5% respectively; time effect, both p < 0.001), while percentage of time sedentary showed a strong trend toward an increase (1.3 ± 5.6%, time effect, p = 0.059), with no differences between groups.

Over the 30‐min testing duration, locomotor activity decreased ( F (3,44) = 88.547, p < 0.001) irrespective of Mn and sex, as all mice habituated to the arena over time (Figure 6 ); there was also a strong trend for Mn‐exposed males to be more active early in the test (during the first 10 min; Figure 6 ; t = 1.989, p = 0.059).

A statistically significant link between AMU and AMR was further determined for sulfonamides ( p = 0.010) and tetracyclines ( p = 0.042), and a strong trend for such a link was also found for fluoroquinolone use and quinolone resistance (all when classified into tertiles; p = 0.059; Table 2 ) among commensal E. coli .

The classical monocytes initially showed a strong trend to be higher in the BCG group ( p = 0.0597), and both groups showed a steady increase in numbers from weeks 36 to 88 (F i g. 3 I).

It is of special interest that in the parasagittal plane, a strong trend in distance from skin to hyoid bone was found, with a cut-off point of 1.28 cm, with a sensitivity of 58% and specificity of 70%, although not significant ( p = 0.0599).

Second, importantly, this study demonstrates that OCT-guidance was associated with a significant reduction in cardiovascular mortality and with a strong trend (p = 0.06) for a reduction in all-cause mortality.

Multivariable analysis revealed a strong trend to poor survival with a STR compared to those with a GTR (HR 1.88; 95% CI 0.9633–3.66, P = .06) ( Table 3 ).

RESULTS/ANTICIPATED RESULTS: Our preliminary results show a strong trend for decreased mortality in the 2PE-exposed group (16.1% mortality (n=31) vs 38.5% mortality in vehicle control (n=26), p=0.06, Barnard’s test).

Additionally, microvascular invasion was associated with a higher risk of progression in the univariate analysis (HR = 2.20, p = 0.050), and although it remained a strong trend in the multivariate analysis (HR = 2.05, p = 0.060), it was just shy of statistical significance.