“did not reach statistical significance”

A favorable trend toward nodal downstaging was observed (ypN0–1 OR 1.57; ypN2–3 OR 0.60), although these differences did not reach statistical significance.

The six minute walking distance challenge test seemed to show a decreasing trend with increasing exacerbation severity but such changes did not reach statistical significance.

In HER-2-positive and TNBC subtypes, we observed a positive trend suggesting that higher percentages of N20-CD8 + T cells may correlate with better outcomes; however, these findings did not reach statistical significance, possibly due to limited sample sizes (Supplementary Fig. 13 ).

The difference between the subgroups using the WOMAC (Table 3 ) global and clinical variables, including pain, stiffness, and function, did not reach statistical significance either, although a possible trend toward a worse baseline condition for the fast group was shown.

The results also showed a trend to less damage in parp-1 o/o mice (Figures 3 and 5 ), although, again, the difference did not reach statistical significance ( p = 0.053, by 1-way MANCOVA fixed effects test).

When the whole cohort was analysed, POSTN-positive breast cancers showed a trend towards a poorer outcome, although this did not reach statistical significance (Additional file 11a,b).

Tumour grade showed a trend towards reduced survival with increasing dedifferentiation, with colorectal cancer related deaths occurring in 34.5% (10/29), 48.4% (171/353) and 56.3% (40/71) of patients with well, moderately and poorly differentiated tumours respectively, although this did not reach statistical significance in our cohort of patients.

The trial showed a trend toward a better outcome in the CCP group but did not reach statistical significance and therefore missed the primary endpoint, which was defined as survival and no longer severe COVID-19 on day +21 after enrollment.

Although dehydroepiandrosterone sulfate (DHEAS) showed a trend towards increase, it did not reach statistical significance but was associated with reduced fatigue, a common symptom in MS.

The intensity of GLuc luminescence in rat blood tends to be higher in the IPP (+) group [IPP (−) vs IPP (+) (AU); 2600 ± 224 vs 2824 ± 241, p = 0.13, Cohen’s d = 0.96]: Although the difference did not reach statistical significance ( p = 0.13), the large effect size in the animal experience (Cohen’s d = 0.96) suggests a notable trend (Fig. 7j ).

Compared to saline-treated mice, the mRNA level of Ehhadh in lung tissue showed a decreasing trend but did not reach statistical significance ( P = 0.0594) in mice with neutrophilia-dominant allergic airway inflammation ( Fig. 2I ).

It should also be added that while the association between PKC δ and disease-free interval did not reach statistical significance, there was a trend towards significance, that is the P -values were 0.074 and 0.052 using univariate and multivariate analyses, respectively.

PFIC responders showed a trend toward increased bile salt concentration and CDCA/CA ratio in bile after PEBD, although these did not reach statistical significance (Figure 3 ), but no increase in cholesterol and phospholipid content.

The results of the meta-analysis were consistent with these findings, with an overall trend toward greater SAF in smokers than in non-smokers for similar age groups, but the difference did not reach statistical significance ( Supplementary Table S7 , Figure S9 ).

Results of the meta-analysis In the randomized clinical trials, the FVC mean difference at 12 months between patients treated with CYC and patients treated with placebo or another immunosuppressant showed a positive trend in favor of the CYC group (mean difference = 4.15%), but did not reach statistical significance (95% confidence interval (CI) = -0.51 to 8.80; Figure 2a ).

Filter used for "age at marriage" produced a large number of false positive and displayed a positive trend but did not reach statistical significance (15/424 vs. 5/336 p = 0.080).

The 5-year DSS and 5-year DFS in the dMMR group only showed a trend of worse survival but did not reach statistical significance.

Younger age as a prognostic factor did show a trend towards improved local and regional control which did not reach statistical significance (borderline significant p values).

There was also a strong trend for putatively tolerant children to be more susceptible to malaria compared to the exposed sensitized children, although this relationship did not reach statistical significance.

Although a decreasing trend was observed for other side effects, these differences did not reach statistical significance ( Table 4 ).

There was a small trend for increased fluorescent intensity following anti-λR treatment of RSV-infected HAE that did not reach statistical significance.

Although there was an increasing trend in the expression of VEGF mRNA with treatment of angiotensin II, it did not reach statistical significance.

S47A mutants showed a trend toward increased basal and ligand dependent activation in reporter assays, but did not reach statistical significance.

In addition, a clear trend was seen towards higher bacterial loads in the pulmonary and systemic compartments of recombinant MIF treated mice, although the differences with control mice did not reach statistical significance ( Figure 4 ).

showed beneficial effects of higher PEEP on morbidity and mortality.[ 43 ] Two other trials with 549 and 767 enrolled patients reported no improvement in survival due to mean PEEP levels of 13±3.5 or 15.8±2.9 cm H 2 O, respectively, in ALI or ARDS.[ 40 49 ] An actual meta-analysis including data from 2484 patients showed a trend toward reduced mortality with higher PEEP even though the difference did not reach statistical significance (odds ratio 0.90 CI 0.72–1.02; P = 0.077).