Barely Significant
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“showed a trend”

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Aged ≥ 70 years ( p = 0.022) remained significantly associated with worse OS, while ≥ 3 metastatic sites ( p = 0.065) showed a trend towards an association with poorer OS. 3.3 Efficacy of Different Treatment Regimens of Anlotinib Regarding the different combination regimens, median PFS and OS varied numerically across subgroups receiving anlotinib monotherapy (PFS, 5.6 months; OS, 11.3 months), anlotinib plus chemotherapy (PFS,
By analyzing the clinical data of 30 patients with BRCA wild‐type recurrence, multivariate Cox regression analysis showed that platinum‐based chemotherapy remained the key factor for prolonging TTSP (Figure 5D ), whereas a PARPi duration longer than 12 months again showed a trend towards a shorter TTSP duration. 4 Discussion The approval of olaparib for patients with BRCA‐mutated advanced OC has catalyzed the rapid development of PARPis and the expansion of their indications.
The main findings can be summarized as follows: VR intervention was associated with significant improvements in hyperactivity/impulsivity and oppositional behaviors; following intervention, neural activity in the right MFG, a region implicated in cognitive control, showed a trend toward normalization, as reflected by decreased PerAF values, while activity in the left PCL, associated with sensorimotor integration, was increased; improvements in inattention were relatively limited, and elevated activity in the left ITG persisted after intervention and was positively correlated with oppositional defiant symptoms.
Based on median intensity values, DW showed a trend toward the largest reduction (approximately 17%), followed by RT (approximately 8%), while HW showed no improvement compared to the unwashed sample; however, none of these differences reached statistical significance ( n = 8 per group), and this observation should therefore be considered a trend rather than a demonstrated outcome.
Although ε4 showed a trend toward increased risk (aOR 1.09, 95% CI: 0.46 to 2.49) and ε2 toward a protective effect (aOR 0.82, 95% CI: 0.24 to 2.36), these did not reach statistical significance after multiple testing correction (BH‐FDR‐adjusted p > 0.05) (Table 2 and Figure 2 ).