“showed a trend”

Although all three patients showed a trend towards reduced CD25 upregulation and CD62L down-regulation upon CD3 and CD3+CD28 activation as well as a small memory T cell pool (CD4 + CD45RA − CD45RO + cells), these results were within the range of normal donor variation (data not shown).

Mothers with MDD showed a trend similar to mothers with GAD.

The NP 311–325 CD4 T cell response in IL-7Rα 449F cells also showed a trend towards impairment, but this was not a significant difference ( Figure S4 ), perhaps due to the lack of a robust response in WT CD4 T cells in these chimeric mice.

The NE re-uptake inhibitor atomoxetine showed a trend for improving several frontal lobe measures of cognitive performance in a small open-label study of non-demented PD patients [ 24 ].

Discussion During the period studied, the data showed a trend toward a decrease in the death rate of ELBW infants, although this trend was not significant.

Their scoring showed a trend to score in the upper third of the scoring range.

Moreover, when we determined the residual metabolic activity of the cta1 Δ/Δ mutant after confrontation with neutrophils, we found that although this mutant showed a trend towards decreased survival, the susceptibility in the killing assay was not significantly increased ( Fig. 5A ).

Furthermore, CDKN1A(p21) expression was associated with better overall patient survival (p=0.045), while CDKN2A(p16) expression showed a trend toward better overall survival, in univariate analysis.

Glucose, Lipids and Insulin Sensitivity Following weight loss, total cholesterol and triglyceride levels significantly decreased (5.40±1.21 vs 4.62±0.85 and 1.1±0.65 vs 0.98±0.56 mmol/L respectively; P<0.05 for both), HDL-cholesterol significantly increased (1.34±0.26 vs 1.55±0.36 mmol/L; P<0.01) while LDL-cholesterol showed a trend toward a decrease which did not reach, however, statistical significance (3.46±1.39 vs 2.81±0.67 mmol/L; P = ns) ( table 2 ).

Patients with a solitary bone metastasis at the time of presentation also showed a trend for improved survival relative to those with multiple bone metastases, although not statistically significant ( P = 0.07).

However, the mutation of CPI showed a trend towards reduced microfilariae in the peripheral circulation ( Figure 5D ).

Application of H-G or either of the P2 receptor antagonists showed a trend that was similar to the reduction observed with DPI ( Fig. 6B ).

Also observed was that the use of knowledge brokers along with access to the online registry of pre-processed research evidence showed a trend towards a positive effect when organizational research culture was perceived at baseline as low.

Results Referral clarity at six months was significantly improved from pre-intervention, and referral content showed a trend towards improvement.

It showed a trend towards improved HI with increasing value of prescribed dose.

The present study showed a trend regarding injury rates depending on month of the year, indicating that there were increased injuries during the month of September, October, January and February.

However, the pooled data showed a trend towards less revision surgery for patients who had undergone total hip arthroplasty compared with those who had undergone hemiarthroplasty.

As for overweight, this showed a trend in the same direction but the effect sizes were smaller and non-significant (multivariable OR 1.18, 95% CI 0.98, 1.42 for overweight vs. normal weight with respect to car size; OR 1.08, 95% CI 0.88, 1.33 for engine size).

In the present study, cell proliferation was significantly affected by the cascade of events in chronic TBI, but while neuronal differentiation showed a trend of similar reduction, it did not reach statistical significance compared to sham control.

Such blunted prostanoid production was paralleled by a reduction in COX-2 gene expression, whereas other pro-inflammatory mediators, namely interleukin-1β (IL-1 β) and -6 (IL-6) showed a trend to increased gene expression.

Additionally, the subgroup in the supplementation arm that had baseline ‘Insufficient’ levels showed a trend towards lower number of zones involved on chest radiograph ( p 0.054) and higher sputum smear clearance ( p 0.05) however, this difference was not statistically significant.

An intra-individual comparison showed a trend towards greater strength in the right hand, though it was statistically insignificant.

Although the intervention showed a trend toward reduced allergen levels, concomitant changes were occurring following Katrina; a natural reduction of mold levels and home renovations and remediation also took place after the storm ( Grimsley et al. 2012 ) and undoubtedly contributed to improvements in asthma symptoms.

Statins showed a trend of reduction in risk of subsequent PD in this meta-analysis, which may be due to a protective role through reduction of oxidative stress. 49 Hypercholesterolemia, obesity, and physical activity could not be included in the meta-analysis due to differences in assessment, and the systematic review found conflicting results.

In contrast, antigen-exposed transgene-negative animals showed a trend to increased right ventricular systolic pressures that failed to reach statistical significance ( Fig. 2 ).