For corticosteroid use at 1 year after diagnosis (Table 5 ), two predictors showed a trend of significance in the univariable analysis ( P = 0.08) and remained significant in the multivariable analysis (via forward stepwise selection and logistic regression analyses) which were female (vs. male) (OR 3.08, 95%CI: 1.02, 9.33) and CD (vs.
Participants receiving PT‐Cy showed a trend towards lower rates of positive CMV specific CD8 + responses (OR 0.44 [95% CI 0.18–1.13], p = 0.08).
Attaining the quasi-optimal/suboptimal joint PK/PD target of CI piperacillin–tazobactam showed a trend toward a higher risk of microbiological failure (33.3% vs. 0.0%; p = 0.08) (4) Conclusions: Real-time TDM-guided optimal joint PK/PD target attainment of CI piperacillin–tazobactam monotherapy may represent a valuable and effective carbapenem-sparing strategy when dealing with non-severe ESBL-producing Enterobacterales secondary BSIs.
In terms of safety, ADCs showed a trend toward fewer grade ≥3 Aes (OR = 0.68, p = 0.08), supporting their improved tolerability compared with conventional chemotherapy, and Diéras et al.
Skin Physiology Outcomes Univariate follow-up tests for lesional skin outcomes showed a trend towards lower skin surface pH values in the CP-G ( F (1, 25) = 3.33, p = 0.080, d = 0.732) indicating a potentially beneficial effect on skin barrier condition.
Compassion measured with the computer task did not change significantly but showed a trend toward increase only in socioemotional dyadic practice (β socioemotional =.08, P =.08; β waitlist socioemotional =.11, P =.06).
However, it should be noted that the RRMS‐OSA group showed a trend towards worse outcomes in several measures, including PSQI ( p = 0.08), FSS ( p = 0.1) and MFIS ( p = 0.15).
Additionally, ConA reduced contraction and relaxation velocity and CQ showed a trend towards a decreased contraction velocity (p = 0.08, Fig. 4 e–f). 4 Discussion Our study revealed that aging is associated with functional impairment of cardiomyocytes and accumulation of autofluorescent protein aggregates, such as lipofuscin.
21.48%), and the IPTW-weighted analysis showed a trend toward lower risk in G2 (OR 0.63, 95% CI 0.37–1.05; weighted p = 0.08), although this did not reach conventional statistical significance.
The inducer effect of calcium supplements on CACNA1C and ATP2C1 showed a trend to increase the expression of the FE genes (ES = 1.51, p -value = 0.08, and ES = 2.03, p -value = 2.23 × 10 −3 , respectively), which was not fully validated in the case of CACNA1C in the other datasets (ES = 1.25, p -value = 0.07, in GTEx; and ES = 1.66, p -value = 2.31 × 10 −3 , in CEDAR), nor validated in ATP2C1 (ES = 2.57, p -value = 1.04 × 10 −3 , in GTEx; and ES = −1.83, p -value = 0.01, in CEDAR).
The frontal cortex of the same animals is characterised by the significant overexpression of 10 mediators and 7 more showed a trend towards being overexpressed ( p < 0.08), with a total of 17 altered mediators representing 22% of the proteins detected (Fig. 8 a, b).
CaWidth (assessed as FWHM), a measure for the heterogeneity of the calcium concentration, showed a trend towards narrower curves in mice treated with FDI ( p = 0.08) and a significantly lower value in FCM-treated mice ( p < 0.001) (Fig. 4 E).
In our meta-analysis, MPR was found to be significantly higher in females than in males, with an odds ratio (OR) of 1.82 (95% CI 1.13–2.93; p = 0.01), while pCR showed a trend to be more favorable in females than in males, but the OR of 1.62 was not statistically significant (95% CI 0.97–2.75; p = 0.08).
One item showed a trend in the opposite direction; boys were more often (16.7%) able to put their hands flat on the ground than the girls (9.5%; Χ2 = 3.29. p = 0.08).
Notably, Observer C showed a trend toward higher scores during interventions ( p = 0.08, r = 0.24).
BMI category yielded a borderline result ( p = 0.05) that did not reach conventional significance, and enthesitis showed a trend ( p = 0.08) that warrants further investigation in adequately powered cohorts.
In contrast, anti-GDNF antibody positivity showed a trend toward an increased risk of elevated FIB-4 index in the univariate analysis (OR 4.03 [1.00-27.13], p=0.08).
Previous ischemic stroke showed a trend toward higher prevalence among patients with LVT recurrence compared to those without recurrence (22.2% vs 9.7%; P = 0.08) whereas most other comorbidities were similar between the groups.
Adults showed a trend toward higher baseline PGA scores compared with children (median PGA 5 (range 3–9) vs. 3 (range 2–9), p = 0.08). 4.3.1.
The motor phenotype of the diffuse-malignant subtype consisted of more PIGD symptoms [PIGD [H(2) = 16.7, p < 0.001, η 2 h = 0.03] and showed a trend towards more bradykinesia symptoms [F(2) = 2.5, p = 0.08, η 2 p = 0.01].
HDM-challenge resulted in the increase of total IgE serum levels in BALB/c mice, which was statistically significant in female mice ( p < 0.01) and showed a trend of increase ( p = 0.08) in males (Fig. 1 A).
Indeed, administration of an intravitreally administered siRNA targeting the REDD1 mRNA (PF-04523655) in patients with diabetic macular edema showed a trend toward improvement in BCVA when compared to focal/grid laser (+5.8 letters with 3 mg PF-04523655 versus +2.4 letters with laser, p = 0.08) ( 18 ).
Insulin treated diabetics (n = 314) showed a trend to higher mortality compared with non-insulin treated diabetics (n = 701, Hazard Ratio 1.5, 95%CI 0.9–2.3, p = 0.08).
Although not significant, children with LBW showed a trend of being smaller than children with NBW, with a strong trend of lower FM in the LBW group compared with the NBW group ( p = 0.08).
60%, p = 0.16) and non-smokers showed a trend towards greater DAS28 improvements than smokers (3.04 vs. 2.35, p = 0.08). 3.2.