“showed a trend”

Plasma insulin levels also showed a trend of increase after αMG injection, but this change was not statistically significant ( Supplementary Fig. 2B ).

C-EV treatment administered before and on the day of MPTP intoxication showed a trend toward increased survival of dopaminergic neurons in the substantia nigra (SN), although the difference was not statistically significant when compared with mice treated with MPTP alone ( Figure S1 A-B).

In our study of B-cell acute lymphoblastic leukemia (B-ALL), we observed that cases positive for NOTCH1 mutations in the PEST domain showed a trend towards increased significance in terms of overall survival (OS) compared to cases with mutations in the HD domain when compared with their wildtype counterparts.

Furthermore, MM patients showed a trend toward higher proportions of PD1+Tim3+ exhausted and terminally differentiated T cells compared to HCs, even though it did not meet the threshold for significance (Figure 1 G-H) .

Although the absence of statistical significance ( p = 0.21), data showed a trend of miR-191-5p overexpression in PCa compared to BPH controls (Supplementary Figure S2 ).

Low-dose fish oil intervention showed a trend towards lower remnant cholesterol, VLDL, and significantly decreased LDL-1 particles, whereas raised concentrations of LDL-5 and LDL-6 compared with the placebo (Fig. 2 B and Table S12 ).

For individual cancers, GLP-1RA use showed a trend toward lower risk for pancreatic (HR, 0.88 [95% CI, 0.68–1.14]), bladder (HR, 0.83 [95% CI, 0.64–1.08]), and breast (HR, 0.93 [95% CI, 0.79–1.10]) cancer, though these differences were not statistically significant.

Transplant-free survival stratified by SHUNT% showed a trend towards lower survival for those with elevated SHUNT% over the entire follow-up period ( Fig. 1 ).

MOCART-2 scores showed a trend toward superior biological healing in the minced cartilage group (mean score: 77) compared to the BMAC group (mean score: 73).

Additionally, findings from the 1-year follow-up study only showed a trend level impact of GBG + MTP on teacher distress (i.e., burnout and stress), while the most robust findings were among teachers working in higher risk conditions (e.g., classrooms with higher rates of student disruptive behavior; Downer et al., 2024 ).

Although hemostasis time did not differ statistically ( P = 0.09), suturing showed a trend toward prolonged duration (median 9.5 [7.25–12.75] min).

The time × treatment interaction was significant, and follow-up contrasts showed a trend-level difference between intervention and control at the 2-month and 4-month follow-up assessments but not at baseline.

Furthermore, among MMRp patients, elevated GSVA scores for CXCR6 + CD8 + T cells showed a trend toward improved prognosis.

In this group, the initiation of psychiatric medication showed a trend toward occurring more frequently after the onset of RIP.

TKV was not only lower among participants who had lost a clinically significant amount of body mass compared to the rest, but also showed a trend toward reduction in this group, suggesting a posible signal of reduced cystic burden.

The scores of sleep quality, anxiety and depression showed a trend across the three assessment time ( Figure 2 ). 3.4.

Interestingly, the levels of the mitophagy marker protein LC3β showed a trend toward decreased levels in the presence of IgG from ME/CFS and PCS-CSF patients ( Fig. 2 D and E), but this difference was not statistically significant.

The number of differentially expressed genes upregulated and downregulated at each time point showed a trend of increasing and then decreasing, suggesting a transitional process of inflammation generation and regression ( Figure 4(f) ).

A meta-analysis of 20 studies involving 14,599 patients established that intracranial arterial calcification (ICAC) detected on routine imaging is independently associated with significantly increased ischaemic stroke risk and showed a trend towards increased mortality. 5 This finding suggests that ICAC may serve as an accessible imaging biomarker for stroke risk stratification.

Although hStrO neurons showed a trend toward increased excitability upon CGP treatment, this change did not reach statistical significance (fig.

Also, patients with a high total immunostaining score showed a trend for shorter OS and RFS (Table 2 ).

Clinically, disease activity scores showed a trend toward being higher in patients with gastrointestinal symptoms (Figure S9A).

The fact that the number of p62/SQSTM1-positive vesicles was not concomitantly increased in the FTD neurons, but rather showed a trend towards a decrease could suggest defective clearance and enhanced fusion of the p62/SQSTM1-containing vesicles.

Overall, results showed a trend that may highlight the contribution of site-effects to classification performance.

In our cohort, severe irAEs showed a trend toward reduced OS when compared to mild irAEs, but they displayed the extension of OS than that of non-irAE.