“showed a trend”

Splenocytes isolated from RALA/ mGPC2 -vaccinated mice showed a trend toward increased TNF-α production by CD4 + and CD8 + T cells, levels higher than those in control groups ( Figures 3 C and 3D).

Furthermore, we observed that across multiple cancer types, patients in the high HICDI score group consistently showed a trend toward poorer prognosis, a finding that provides preliminary exploratory evidence to support the potential generalizable application of this integrated model.

Although VAP and gastrointestinal bleeding did not reach statistical significance, the incidence rates in the intervention group showed a trend toward clinical benefit (an absolute reduction of 3.3% for VAP and 10.0% for gastrointestinal bleeding).

The study found that adding a gp100 peptide vaccine to ipilimumab (a CTLA-4 inhibitor) did not improve its efficacy and instead showed a trend toward reduced response compared to ipilimumab alone 39 .

Twenty-nine participants from the waitlist also showed a trend of improvements in Global PSQI and daytime dysfunction between weeks 6 and 12.

In macrophages, the combination group showed a trend toward elevated CD80 + expression and significantly increased CD86 + expression (both M1-associated markers), confirming polarization toward a pro-inflammatory, antitumor phenotype.

While no statistically significant difference in major adverse events was observed at 30 days, follow-up analyses at 90 days showed a trend toward improved outcomes with Impella, reaching statistical significance in per-protocol and selected post hoc analyses. 22 , 27 For the first time, the most recent European guidelines explicitly recommend the use of an mAFP in selected patients undergoing HR-PCI at experienced centres (class IIb recommendation). 1 Furthermore, in patients with significant functional MR, MCS with an Impella device offers a compelling mechanistic option.

Due to the small sample size, the inter-subgroup difference did not reach statistical significance; however, the cure rate for Pseudomonas species showed a trend toward being lower than that for Acinetobacter species.

β2m showed a trend toward reduced mitochondrial ATP production and increased glycolytic ATP production, but these changes were not statistically significant, suggesting that β2m did not measurably redistribute ATP sources under the basal assay conditions used here.

Although the two groups (CG and EG) showed a trend toward separation, a partial overlap was observed, indicating that the transcriptional differences between normal and emphysematous lungs are not dominated by the first two principal components.

Similarly, Ldha knockdown in LM8 osteosarcoma cells showed a trend toward increased ROS levels (Supplementary Fig.

Overall, female animals showed a trend of more favorable recovery than males, though many of these differences did not reach statistical significance.

Nevertheless, the model group showed a tendency toward reduced mature/antral follicles and increased atretic follicles, whereas CoQ10, Base, and Base + U treatment showed a trend toward improved follicular distribution.

Movement extent showed a trend toward larger values in the affected limb, suggesting reduced movement efficiency.

Cardiac aetiology showed a trend toward lower odds but did not reach statistical significance (OR 0.11, 95% CI 0.01 to 1.07, p=0.068).

First, compared to T1, first-generation college students’ self-esteem levels declined slightly at T2, while their academic performance improved slightly; their anxiety levels remained within the mild range and showed a trend of gradual alleviation.

Subgroup analyses showed a trend towards increased mortality in depression (HR=1.73, 95% CI 0.99 to 3.03, I2=67%) and anxiety (HR=1.21, 95% CI 1.00 to 1.47).

RF ablation showed a trend toward smaller isolated LAPW area (6.1 ± 3.9 cm2), although this difference compared with P-PFA did not reach statistical significance (p = 0.087).

The propofol group showed significantly increased VRT, indicating poorer sustained attention, while the sevoflurane group showed a trend in the same direction.

Female patients showed a trend toward better functional outcomes (lower mRS scores); however, this difference did not reach statistical significance (Mann–Whitney U = 325.5, p = 0.374). mRS data at discharge and at 90-day follow-up are presented in Figure 4 below.

Tumor size ranged from 2 to 40 mm but showed a trend towards larger lesions in certain anatomical areas, such as the palate.

Leukemia relapse post-HSCT ( p = 0.165) showed a trend of being associated with 12-month mortality.

Only standard-dose apixaban showed a trend toward lower mortality compared with VKAs (HR 0.87, 95% CI 0.76–1.00) ( Supplementary Figure S4 ).

Although subgroup-based interpretation was not the primary focus of this study, exploratory analysis showed a trend toward favorable outcomes in cases of pedicle screw-related irritation ( Table 2 ).

With the tempering temperature increasing from 520 °C to 640 °C, the strength of the studied steel showed a trend of first decreasing, then stabilizing, and then decreasing again, while the plasticity showed a stable upward trend.