M-CLL subset #4 was associated with lower CLL-IPI scores and younger age at diagnosis; in both cohorts, these patients showed a trend towards better outcomes versus other MCLL.
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At this time point, β‐cat ex3 iDCX neurons and control neurons showed a comparable branching pattern; surprisingly, β‐cat ex3 iDCX neurons showed a trend toward decreased total dendritic length, while Sholl analysis revealed a reduction in the length of the terminal dendrites (Fig 3 D).
In addition, the T cell markers Cd3g and Cd8a showed a trend towards higher expression in NRF2 knockout tumors (Supplementary Fig. 7B ) and quantification of CD3 + immune cell infiltration into control and NRF2 knockout melanomas showed a similar trend (Supplementary Fig. 7C, D ).
Pad2 –/– significantly reduced CLP-induced permeability in lung and kidney, and it showed a trend toward the decreased permeability in spleen and liver ( Figure 4A ), suggesting that KO of the Pad2 gene could ameliorate sepsis-induced organ dysfunction by reducing microvascular permeability.
At 2 months of age, smKO mice showed a trend of increased body weight without statistical significance as compared with WT control ( Fig 2E ).
While we did not perform individual treatment controls in these experiments due to restricted numbers of available CD89 Tg animals, our previous work ( 10 ) and results from Figure 5 (below) showed that while IFN-γ; showed a trend toward protection, it alone was not sufficient to induce a statistically significant lung CFU reduction in any of our experiments.
Despite similar initial blood draw levels, sustainers showed a trend toward greater anti-S IgG ( Figure 3 J) and significantly more anti-RBD IgG ( Figure 3 L) compared to decayers in draw 3, consistent with the notion that a unique feature of sustainers is anti-virus IgG maintenance in contrast to initial magnitude.
17 – 24 The current study showed a trend of increase in the severity of DKA among children with T1DM over the study period with an overall frequency of 12.3%.
The only small, controlled trial using galantamine showed a trend for efficacy in reducing TD that was reversed after switching to placebo [ 108 ].
It showed a trend of microbial diversity similarity among participants.
Consistent with the results in cultured keratinocytes, Igfl3 and Tfcp2l1 showed a trend towards decreased induction in the epidermis of MR EKO relative to CO (Fig. 6 a,b).
However, 8 days post-inoculation, all transcripts tested showed a trend of lower levels in the lox3 mutant plants.
(C) XPO1 high expression showed a trend of unfavorable prognostic effect on PFS in MYC -rearranged ( MYC -R + ) DLBCL.
Patients with high tumor SMARCA2 (BRM) protein expression showed a trend towards a better overall survival, although this relationship did not reach statistical significance.
Plasma levels of sCD14 showed a trend of increase in SIV+ group (10.86 ± 5.994) in comparison with NON_SIV (6.47 ± 2.54) and ART groups (8.89 ± 4.30) but did not reach significant difference (Fig. 8 B).
A comparison between gene expression fold changes and copy number variation of the differentially expressed genes (log2-fold change > ± 1) for each progeny cell line compared to HEK293 showed a trend of gained gene copies amongst the majority of genes with up-regulated mRNA levels (Supplementary Fig.
Encouragingly, SIGLEC9 expression showed a trend for an inverse correlation with MUC1-ST expression suggesting the down regulation of the receptor upon engagement (Supplementary Fig. 5d ), which was also observed at both the RNA and protein level in our in vitro studies (Supplementary Fig. 3f ).
The bone length showed a trend similar to the body weight.
showed a trend for more rapid decrease in bone pain score at one month in favor of zoledronic acid compared to oral ibandronate ( 22 ).
Although there was no significance, the reduced lung lesion ratio in the CHM group showed a trend of pulmonary inflammatory resorption.
5 ), whereas the right region showed a trend ([22 ,6, − 8], pFWE (cluster) = 0.07, t = 4.14, k = 129, Fig. 5 ).
Although there was considerable variability between animals, SKT82 and DMR7 treatment showed a trend towards lower insoluble phosphorylated tau in the ipsilateral and contralateral sides of AD-tau injected 5xFAD mice.
The current study showed a trend similar to that in our previous echoic memory study (Inui et al., 2010a , 2010b ; Kinukawa et al., 2019 ).
When surgery was compared to non-operative management (NOM) and to cholecystectomy, the mortality rate showed a trend favouring surgical management.
The correlation between the left SN SUVR and the MFIS physical subscale showed a trend but did not attain statistical significance (r = 0.56, 95% CI −0.02 to 0.86).