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Moreover, the correlation between the GSN level and brain atrophy were analysed, with the increase of global cerebral atrophy-frontal (GCA-F), PA and MTA scores, the plasma or CSF GSN showed a trend of initially increasing and then decreasing ( online supplemental figure S6A-F ), and the plasma GSN was significantly positively correlated with GCA-F and MTA by Spearman correlation analysis (GCA-F: r=0.256, p=0.020; MTA: r=0.250, p=0.038).
<i>GSN</i> gene frameshift mutations in Alzheimer's disease.
J Neurol Neurosurg Psychiatry · 2023 · PMC10314070
Besides, HDMs‐sensitized asthma patients combined with pollen and animal dander sensitization (Class 1) showed a trend of sensitization during the school‐age children period, indicating the probability of poly‐sensitization was increased with rising age and exposure to various allergens (32.43% vs. 17.80%, p < 0.05) (Figure 5A ).
This contradicts previous national studies in Norway based on data from the same unbalanced cohort of 1994–2014, which showed a trend towards more part-time work (<37 hours/week) for specialty registrars and senior hospital consultants (6.3% to 10.0%), specialists in private practice (14.8% to 25%) and doctors in academia (3.9% to 12.5%). 31 Compared with doctors in our data from 2016 to 2019, the proportion of part-timers was
Conclusions With application of best practice as known by the time of the first three waves of the pandemic, our study failed to identify a significant improvement in mortality rate when comparing the different waves of the COVID-19 pandemic, notwithstanding, the sub-analyses showed a trend in mortality reduction in the third wave.
It is noteworthy that the subgroup of patients with prematurely terminated isoflurane, and in particular those experiencing an elevated P aCO 2, had a significantly higher peak inspiratory pressure, lower lung compliance, and showed a trend towards higher ventilator minute volume in the period -24 h to -1 h prior to the implementation of the ACD when compared with the patients with continued isoflurane sedation ( Table 5 , Supplementary Table S1 ).
Statin therapy showed a trend for reducing the risk of all-cause mortality in patients with high-risk profiles, such as older ( \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\ge$$\end{document} ≥ 65 years old) patients, female patients, those with multiple comorbidities (such as patients with diabetes, CHF and a higher CCI value).