Excerpts

Despite ICOSLG, only being higher expressed in patients with an above-median PFS at T 0 , there was a trend towards patients with above-median PFS rates having higher levels of ICOSLG at T 2 , which was on the threshold of significance ( p = 0.051), while no trend was observed at T 1 ( p = 0.29). 3.3.

When TMB score was added to the adjusted variables above, the 2tPD-L1 more accurately could predict survival; however, this, too, did not quite reach significance ( p = 0.051) ( Table 4 ). 3.6.

Furthermore, in the multivariate analysis it was shown, that tumor stage was the main predictor for DFS and SPARC expression just failed significance with p = 0.051.

While results for 2-year progression-free survival show a strong trend toward favoring rituximab treatment, they were not statistically significant, but only by a slight margin (HR 0.52, 95% CI 0.32–0.86, p = 0.051).

All six lung cancer patients had positive aCL antibodies, and colon cancer patients had a borderline significant association ( p = 0.051).

Although the median time from first-cycle LDT to first-cycle follow-up imaging approached significance ( p = 0.051), and the greatest impact on TTP was HCC imaging delay.

Only N0 was shown as an independent factor ( p = 0.049), and R0 almost reached statistical significance ( p = 0.051) in multivariate analysis of ENT1 protein expression, analyzed by immunohistochemistry and covariates ( Table 5 ).

Body weight loss in the C26 hosts ( Figure 1 A) was slightly, but with borderline significance ( p = 0.051), attenuated by exercise ( Figure 1 A,B), while no differences could be observed between sedentary and exercised controls ( Figure 1 A).

A near-significant relationship was identified between DR type and tumor differentiation grade (χ 2 = 9.448, p = 0.051), with mature stroma most common in Grade 1 tumors, keloid-like stroma in Grade 2, and myxoid stroma in Grade 3.

The 3-year DFS was 91.7% in the alectinib group and 60.7% in the ChT group, albeit with a borderline significant benefit in DFS (HR: 0.17, 95% CI 0.02–1.28, p = 0.051), most likely due to the small sample size.

When stratified by cell-of-origin, the association between rs822336 and RFS was borderline significant in ABC-DLBCL (Kaplan–Meier, p = 0.051), whereas no association was observed in the GCB subtype ( p = 0.300).

Consistently, the recessive model approached but did not reach significance (OR = 1.606, p = 0.051).

No prognostic factors were significantly associated with early or late PCS complications, with thrombosis approaching significance ( p = 0.051).

While no statistically significant differences were identified between arms, p -values for time-by-arm interactions approached significance (e.g., p = 0.051). 3.7.

However, when demographic factors and NSCLC stage were adjusted for in a Cox proportional-hazards model, abnormal galectin-1 levels were not significantly associated with decreased OS, yet with borderline significance ( p = 0.0513), which is possibly due to our relatively small sample size.

Finally, a Cox proportional hazards model that included the demographic factors in Table 1 and lung cancer stage showed that abnormal galectin-1 levels were not significantly correlated with OS, with a hazard ratio of 2.928 (95% CI of 0.9940 to 8.625), yet it was borderline significant with p = 0.0513.

Instead, the increased expression of miR-146a-5p in ulcerated melanomas was borderline significant ( p = 0.0513) ( Figure 4 ).

The same participants saw relationships trending towards significance for dietary zinc intake for Pt-S and platinum resistance (Pt-R) ( p = 0.0514 and 0.0731, respectively) and dietary B12 intake and Pt-R ( p = 0.0514).

4.0%), approaching significance ( p = 0.0519).

We found this association between the FOXL2 p.C134W mutation status and FOXL2 positivity by IHC to be marginally statistically significant (mid- p -value = 0.052).

The 5-gene risk score calculated as PC1 was associated with the partial significance of worse prognosis (HR: 1.27, 95% CI: 1.0–1.61, p -value = 0.052), and the low-risk group was partially associated with better disease prognosis (HR: 0.72, 95% CI: 0.51–1.03, p -value = 0.073), as shown in Figure 2 A. 3.3.

Finally, MCT1 was overexpressed in 6/10 NSCLC samples (60%); however, the difference between the tumor tissues (median = 7.07) and the adjacent tissues (median = 9.51) was marginally statistically significant ( p = 0.052) ( Figure 2 ). 3.3.

In survival analyses we observed that high basal levels of IL-6 (over 6.0 pg/mL) were significantly associated with lower OS ( p = 0.029) and were almost significantly associated with lower PFS ( p = 0.052) ( Figure 5 C,D).

UICC-stage thereby missed statistical significance, however, a clear trend could still be observed for advanced UICC-stages (III & IV) to impair the OS of tumor patients (HR 1.486; 95% CI 0.996–2.217, p = 0.052).

Type of surgery showed borderline significance ( p = 0.052), while no lifestyle factors showed any association.