Barely Significant

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an increasing trendp < 0.051.0× alphagold
While low-dose CGEF exhibited an increasing trend in p-PI3K, all doses of CGEF significantly restored phosphorylation levels of PI3K/AKT/GSK3β and CREB ( p < 0.05), indicating its potential to counteract CSR-induced disruptions in these signaling pathways ( Figure 12 ). 3.11.