Excerpts

PD-L1 expression has, also, significant impact on overall survival (OS) ( p = 0.045), while for PD-1 expression only a positive trend was seen for OS ( p = 0.059) [ 36 ].

No effects were observed for groups, but there was a clear trend showing higher GR-positive cells in the PSS-exposed groups (F(3, 52) = 2.6, p = 0.059).

There was a correlation of borderline significance (CC = 0.152, p = 0.059) between Siglec-8 expression and tumor grading (G).

In our study, the MMP-1 rs1799750 1G2G genotype (compared to 2G2G) showed a trend toward increased arterial thrombosis risk (OR = 3.200, 95% CI 0.956–10.714, p = 0.059), indicating a possible association that warrants further investigation in larger cohorts.

RT-PCR revealed that BTG1 siRNA-transfected cells exhibited 1.18- and 1,94-fold increases in MMP2 and MMP9 mRNA expression levels compared to vehicle-treated control cells, with marginal significance ( p = 0.059 and p = 0.089, respectively; Figure 2 B).

This differential of FASS-LTP levels between the cohorts just failed to reach significance ( p = 0.059, ns) using the non-parametric one-tailed Mann–Whitney test.

A two-way ANOVA on synaptic density indicated a trend toward significance on ketamine (F [1, 33] = 3.798, p = 0.059) but not CHIMERA (F [1, 33] = 1.193, p = 0.283) as shown in Figure 4 F.

Moreover, CCL11 was among the top core enriched genes with respect to angiogenesis in the non-inflamed UC mucosa, with a borderline significant upregulation (FDR; p = 0.059), but significantly upregulated in the inflamed UC mucosa, and present in a IBD GWAS loci.

Indeed, we noticed a considerable increase in BDNF mRNA levels ( p < 0.0001) and a value near to significance for Fgf-2 ( p = 0.059) in irisin-treated mice compared to controls.

We also noticed a trend towards significance in IP-10/CXCL10 ( p = 0.059).

Moreover, ovarian cancers that were triply positive for intraepithelial CD4 + , FOXP3 + , and CD25 + cells showed a trend towards increased survival ( p = 0.059) [ 55 ].

Two-way ANOVA of the data indicated a nearly significant effect of genotype on the percent active responses (F 1,19 = 4.02, p = 0.059).

Significant main effects of sex ( p < 0.0001) existed for all four muscles, while a main effect of tumor group only existed for the EDL muscle ( p = 0.0011) and approached significance for the Tibialis Anterior muscle (TA; p = 0.0592), representing lower muscle weights in tumor groups.

non-injured p = 0.031; Figure 7 B) and a trend toward significance in the caudal zone at 7 dpi (F 2,6 = 4.48, p = 0.06; Tukey test p = 0.051; Figure 7 B).

However, the three RGL1 variants linked to HBV reactivation in the discovery cohort demonstrated marginal significance ( p = 0.06) and consistent directional effects in the replication cohort ( Table 1 ).

As shown in Figure 3 c, A2M levels for the elderberry condition at 6 months were significantly higher than baseline [ t (20.00) = −2.73, p = 0.01, g av = 0.78, moderate–large effect], and trending towards significance for higher values than 3 months [ t (20.00) = −1.99, p = 0.06, g av = 0.24, small effect] in post hoc comparisons.

Using the fixed-effects model, we did not find a significantly greater FBG level reduction in the AGO group than SSRIs; however, a trend towards significance has been observed ( p = 0.06).

The expression of LRb transcripts in the VMH/DMH was not significantly different between sheep groups; however, a trend close to significance ( p = 0.06) was observed in the Lean-R group.

The trypsin-like domain showed a statistical trend towards reduced proteasome activity in ICM tissue (0.78 ± 0.11 μU/mg), compared to DCM (1.06 ± 0.08 μU/mg) and control (1.00 ± 0.06 μU/mg, p = 0.06) tissue ( Figure 1 B). 2.2.

There was a strong trend ( p = 0.06) for RG but not CP diminishing the AUC for IkBα degradation.

Pooled univariate analysis of these studies did not quite reach significance ( p = 0.06).

Association of TIM-3 and LGALS9 Polymorphisms with Clinical Features of ccRCC Patients After stratification by gender, we found that, similarly to the relation observed in the whole ccRCC group, the genotype distribution of rs4794976 differed between patients and controls ( Table 2 ), and this difference was close to significance ( p = 0.06) in female patients.

However, we observed a decreasing trend for LDH-A staining ( p = 0.06, n = 4), showing a potential role in the ratio of decreased lactate to pyruvate ( Figure 4 D).

Examination of the model investigating the statistical interaction between STAT1 and TGFB2 showed that there was a borderline significant increase in HR for the TGFB2 high group of patients (HR (95% CI range) = 1.84 (0.97–3.46); p = 0.06) There was a significant increase in HR for the STAT1 high group of patients (HR (95% CI range) = 2 (1.08–3.71); p = 0.029), accounting for significant impact of age at diagnosis (HR (95% CI range) = 1.03 (1.01–1.05); p = 0.005).

Two-way ANOVA with virus treatment and time after HFS as independent variables and fEPSP slope as dependent variable detected a significant treatment x time interaction (F(158, 632) = 2.4, p < 0.0001), a main effect of time (F(79,632) = 4.2, p < 0.0001), and a strong trend towards main effect of treatment (F(2,8) = 3.9, p = 0.06; Figure 5 h).