Excerpts

According to stratified analysis results, it was possible that males, age < 40 and ≥60 years old, non-Hispanic Whites, those who declared their marital status to be single, the low and middle group of poverty-to-income ratio, 25 < BMI ≤ 28, those who had smoked <100 cigarettes and ≥100 cigarettes in life, those who were without hypertension, and those who were without diabetes had higher blood eosinophil counts, with increasing blood Pb concentrations displaying a significant trend ( p < 0.05).

ANOVA showed that this factor, the derived eABR type, was marginally significant F(2, 14) = 3.62; p = 0.05.

The total OAG-F scores of the survivors indicated a significant downward trend, whereas the scores demonstrated an increasing trend in non-survivors ( p < 0.05).

Beyond the top eight protein networks influenced by SARS/MERS infection, our analysis shows that Transmembrane Serine Protease 2 (TMPRSS2), a protein recently proven fundamental for SARS-CoV-2 entry in the cell [ 64 ], interacts with the viral Spike protein S ( Figure 1 ), and it is downregulated by beta-coronavirus infection ( Figure 3 ), although at borderline significance and not amongst the top eight ( p = 0.05, Table S2 ).

These included female sex (OR 1.31, 95% CI 1.07–1.60, p = 0.001), previous CABG (OR 1.6, 95% CI 1.18–2.17, p = 0.03) and atrial fibrillation (OR 1.84, 95% CI 1.47–2.29, p < 0.001) Patients with renal dysfunction were also at increased risk of readmission with a strong trend towards significance (OR 1.40, 95% CI 1.00 to 1.96, p = 0.05).

The Cox regression with Firth’s penalized maximum likelihood analysis revealed that only MACE (χ 2 = 23.6; HR 9.49 (3.63–30.72); p < 0.001) was independently associated with increased risk of CVD death, whereas the effect of age did not reach statistical significance (χ 2 = 3.8; HR 1.02 (1.00–1.09); p = 0.05) ( Figure 3 ). 3.3.

The remaining nominally significant associations ( p < 0.05) were considered to provide “weak” evidence.

Zorzato et al., in a recent meta-analysis involving over 5000 patients, did not find a statistically significant association between intrauterine manipulator use and recurrence or survival, though the hazard ratio for recurrence approached significance (HR: 1.52, 95% CI: 0.99–2.33, p = 0.05) [ 14 ].

A negative trend between N100 amplitude and disease duration was also detected (r = −0.468, p = 0.050).

The AUC of the Inception-ResNet-v2 (AUC 0.876 (95% CI 0.873–0.879)) was higher than the AUC of the worst performing endoscopist with a marginal significance (AUC 0.723 (95% CI 0.662–0.779), p = 0.05). 3.4.

A meta-analysis performed on isoflurane only showed a trend ( p = 0.05) towards a reduction in mortality in a subgroup of high-quality studies comparing isoflurane to propofol in cardiac surgery [ 52 ].

Residual urine volume <950 mL/day showed borderline significance (OR: 2.36, 95% CI: 1.00–5.56, p = 0.05), while albumin showed a non-significant trend (OR: 0.99, 95% CI: 0.98–1.00, p = 0.07) ( Table 3 ).

Longer REM sleep duration showed a similar trend, although marginally non-significant (B = −0.02; OR = 0.98; p = 0.05), implying that REM architecture may modulate bruxism expression, potentially through its effect on arousal thresholds and muscle activation.

For the KOOS Activities of Daily Living domain, the intraosseous PRGF group also demonstrated significantly better results at 6 months ( p = 0.007) and 12 months ( p = 0.002), though the difference at 3 months did not reach statistical significance ( p = 0.050). 3.3.

Results showed a higher survival rate for patients without vocal cord palsy, while those without IONM and with palsy had the worst survival rate, which approached marginal significance ( p = 0.05–0.1). 3.4.

We performed a test for excess significance to evaluate whether the number of studies reporting nominally significant results ( p -value < 0.05) is greater compared to their expected number [ 24 , 25 ].

a positive association between urine BPA and E2 was observed with borderline significance among women in the BPA-exposed group ( p = 0.05) [ 24 ].

Of note, the independent role of Arab ethnicity was of borderline significance ( p = 0.05) and may have been the result of factors we did not encounter in our analysis. 5.

ADC presented a borderline significant discriminatory power (AUC 0.600, p = 0.05), with a significantly lower AUC compared with the SUVavg and short-axis diameter ( p < 0.01 and p = 0.03, n = 162). 3.5.

Additionally, women had a better OS than men, with borderline significance ( p = 0.05).

Smoking history approached significance at p = 0.05, with an OR of 2.01, indicating that being a current or former smoker could double the risk of neurological signs compared to never smokers.

After adjustment for gestational age and birth weight, the risk of ventilatory support was borderline significant for Group 2 (adjusted OR 3.06; 95% CI 1.00–9.37; p = 0.05) versus Group 1 (reference).

10.3%), but it did not reach statistical significance ( p = 0.05).

Anxiety scores (HADS-Anxiety) showed a trend toward improvement in the intervention group, reaching borderline significance at T48 ( p = 0.05).

Notably, there was a trend towards a higher rate of chorioamnionitis in the ADHD group that did not reach statistical significance ( p = 0.05).