Excerpts

These differences were highly significant, encompassing the entire Mr ROI (Fig. 7c ).

6b ) and the various yeast conditions, yielding moderately significant p -values that ranged between 1e-3 to 1e-5 (see Supplementary Data 7 for precise values).

No temporal changes in intra-host diversity were observed in Manhiça, while in Ilha Josina, there was an increasing trend over time in polyclonal infections, although not statistically significant (Fig. 2B ).

Consequently, we could not establish a clear trend between the MIC and SPs like the slope or simple statistical SPs such as the variance median or mean.

Consequently classifiers based on closed-world training, having no capability of adapting to different regimes or unexplored physics, present some quite significant practical flaws.

After filtering for highly significant interactions ( q < 0.01), we identified a total of 160.000 chromatin loops, capturing Enhancer-Promoter (E-P), Promoter-Promoter (P-P) and Enhancer-Enhancer (E-E) contacts with a similar distribution among the analyzed samples (Supplementary Fig. 3d ).

For RFS, there is a weak trend favoring the Cy-pretreated participants (HR 0.79, 95% CI, 0.52 to 1.19, Supplementary Fig. 1B ).

We also ran multivariable analysis for RFS excluding arm, and no covariates were significant, but age, sex, and advanced disease status approached significance (Supplementary Table 6 ).

In contrast, the infiltration level and predictive role of RSPO1 + fibroblasts in predicting patient prognosis showed a trend opposite to that of POSTN + fibroblasts.

We found an overall trend of elevated Treg infiltration with decreasing Th17, CD4_Tem, and CD8_Tem proportions during HNSCC progression, which indicated the transition from an immune-activated TME to an immune-exhausted TME.

As an overall trend, mutant alleles accumulated progressively in the Maternal-F lineage until virtually no WT alleles remained, while in Paternal-F lineage, even at the endpoint of adulthood, approximately 60% of WT alleles persisted, in line with our single time point experiments (Fig. 4a, d , Supplementary Fig.

As expected, there was a larger number of trials (8/75) that had an insignificant (7/75) or marginally significant (1/75, whether it is significant depends on not correcting for multiple tests) sex comparison relegated to the supplementary information; hence, Trialtrove curators missed the sex comparisons in those 8/75 publications.

Statistically significant main effects were subject to Tukey’s highly significant difference (HSD) multiple comparison procedures to assess differences between factor levels.

Our previous study of mosquito delivery of ZIKV to mice found a highly significant increase in neutralizing antibody titer with increasing virus dose estimated via forced salivations 56 .

Both mouse strains showed a trend toward a decrease in dendritic cells and macrophages; in particular, PTRMs and M2 macrophages were decreased, resulting in an increased M1/M2 macrophage ratio in both the GT and PRT, that is, a polarization shift of the macrophage population (Fig. 6d, e , Supplementary Fig. 26 ).

Additionally, the refractive index of the pV4D4 films showed an increasing trend as the monomer-to-initiator flow ratios decreased (Supplementary Fig. 15c ).

Accordingly, ELISPOT showed a trend towards reduced number of NP8 reacting IgG1 secreting LLPCs in CK bone marrow (Supplementary Fig. 4i, j ).

To investigate whether the wrinkled surface phenotype of ws fruits is caused by the accumulation of phytotoxic SGAs compounds, we assessed SGAs content in fruit extracts by UPLC-MS revealing highly significant changes in γ-tomatine compared to other metabolites (Fig. 1e , Supplementary Fig. 3a–f ; Supplementary Data 5 ).

As the applied voltage increases, the integrated E A , i.e., the generated Joule heat, as well as the temperature reached, show an increasing trend (Fig. 1c ).

The Co/Ir ratios of SI 4 C 1 , SI 6 C 1 , and SI 8 C 1 showed a decreasing trend from SI 4 C 1 , SI 6 C 1 to SI 8 C 1 as shown in.

A decreasing trend was observed for all programs except UCLUST, which almost exclusively created singleton (i.e., unclustered) clusters (Fig. 3 ).

While the overall transition energy is 23500 cm −1 (425 nm), which is too low in comparison with experiment, the variation with the torsional angle shows a clear trend with a maximum transition energy for the minimum of the S 0 potential and a minimal transition energy for the maximum potential.

We found a clear trend in phylogenetic signal for the UC chromosomes compared to the ENAA chromosomes (Supplementary Fig. 16 ).

Pairwise differences in exposure across low, medium, and high provisioning areas were highly significant in all cases (Supplementary Table 2 ).

However, the mean apparent moduli show an increasing trend as c TMC increases from 0.05 to 1 w/v% (from PA1 to PA3) with values of 1.12 ± 1.38 GPa, 1.51 ± 1.61 GPa, 2.50 ± 1.73 GPa, respectively (Fig. 5i ).