Excerpts

S 1b ), we have mainly considered the conclusion obtained with RT-COV (marginally significant), because both the RT variability and mean RT decreased in this case (see Methods, Data analyses).

An initial temperature was set for each lake, expressed as the value of the linear function of RHLSWT in 1985 for LSWT with a positive trend, and as the value of the linear function of LSWT in 1985 for LSWT with a negative trend.

Results The frequency of air temperature extreme heat events in China has followed an increasing trend, albeit with notable regional variability.

Compared with the SAP group, the CA-SAP group showed a trend toward a higher MPR rate in patients with MSI-H (66.7% [2 of 3 patients with CA-SAP] versus 0.0% [0 of 3 patients with SAP]) than in those with microsatellite stability (MSS; 32.6% [15 of 46 patients with CA-SAP] versus 19.1% [9 of 47 patients with SAP]).

In the SP, related to the large interannual variability, none of the three components shows a significant trend, yielding no significant trend in the energy.

Or both annual maximum discharge series derived from the GCM and PRISM have a significant trend, but of opposite sign.

In addition, the mitochondrial compartment length showed a decreasing trend when comparing the 5- and 60-min postphotoactivation periods in VAP KD but not in SNCA and SRGAP2 KD (Supplementary Fig. 4a, b ).

This information may be highly significant for the future design of more effective tumor-targeting NPs.

The bottom line of all these numerical findings is that the same system exhibits a quite significant response to the periodic driving away from thermal equilibrium, but hardly shows any reaction to the same driving as the unperturbed system approaches thermal equilibrium, or if it already started out near thermal equilibrium (stalled response).

The TC intensification rate (IR) also shows an increasing trend; and this trend increases with the quantile of IR (Supplementary Fig. 1c ), contributing to the overall increase in TC intensity.

There were also several nominally significant CpGs in close proximity to this probe with consistent direction of effect, confirming hypermethylation in this region (Supplementary Data 4 ).

Furthermore, Cox proportional hazards model analysis 38 indicated that five of the transcriptomic markers ( STMN1, WDR12, AZIN1, MAD2L1 , and MCM4 ) had a significant association with response to Enzalutamide (Wald p value < 0.05, Supplementary Data 5C , see Methods), yet many of them were borderline significant and did not outperform MYC and NME2 (Supplementary Data 7C ).

These had little effects on the relationships found: Chl a emerged consistently as highly significant and the NBSS-temperature relationship remained non-significant.

As expected, the resulting reconstructions showed a clear trend of decreasing resolution as the tilt angle is increased (Fig. 1a ); at 0° stage tilt, the resolution is 2.3 Å, but the resolution drops to 2.8 Å at 30° stage tilt, and 4.0 Å at 60° stage tilt.

At the individual level, we observed a decreasing trend in the abundances of Staphylococcus and Corynebacterium from the skin to GI tract (Supplementary Fig. 2B ).

We observed a weak trend whereby longer transcripts are better enriched (Fig. 4b and Supplementary Fig. 4c ).

2d ) showed a trend, whereby the intensity increased for the peak at ~1.0 V, while the peak at ~1.4 V lost intensity.

Of importance, there was a strong trend supporting a reverse correlation between DLDA score and CD8 lymphocytic infiltration in posttreatment samples suggesting that viral replication plays an important role in the observed posttreatment remodeling of tumor microenvironment.

A notable trend revealed in this work is the gradual decrease of OGT during Asgard evolution.

5e ) showed a decreasing trend from layer 4 to layer 2/3, and the reduced biases were significant between layer 4 (granular, G) and 2/3 (supragranular, SG) (Fig. 5d , G vs.

Along the ventral pathway from V1 to V4, red bias against green peaked in V1 and then declined, whereas blue bias against yellow showed an increasing trend.

The latter results indicate that while the ecological advantage of genomovars DW07 and CZ05 at high-salt conditions may be significant, it is apparently not strong enough to purge diversity within the species (i.e., completely outcompete remaining genomovars), and genomovars that may be less-adapted to high-salt concentrations (e.g., CZ34 and CM11) appear to survive such (unfavorable) conditions, presumably as (viable) members of the rare biosphere.

As the float moved to the edge of CE 1, the temperature displayed an increasing trend, while nitrate, Chl and POC showed a decreasing trend (Fig.

Ten loci showed nominally significant effects in the HUNT study in accordance with the expected statistical power (Supplementary Data 9 ).

We observe no difference at the single-neuron level, though our W-maze results are only slightly non-significant (Supplementary Figs. 5 C and 7 E).