Excerpts

Compared with Q1, the adjusted ORs were 0.86 (95% CI: 0.67–1.12) for Q2, 0.74 (95% CI: 0.56–0.97) for Q3, and 0.62 (95% CI: 0.46–0.82) for Q4, with a significant trend across quartiles ( p for trend < 0.001).

NEC incidence was highest in the control (60%), IV arginine (64%), and oral citrulline (62.5%) groups, while donor human milk showed a trend toward lower NEC incidence [ 40 ].

Crucially, the VLCD intervention was associated with a highly significant within-group reduction in parameters of permanent chromosomal damage, effectively halving the frequencies of micronuclei and nuclear buds, independent of baseline variations, in adjusted multivariate regression models.

When stratified by sex, this difference showed a tendency towards significance in men ( p adj. = 0.075), but not in women ( p adj. = 0.729).

However, none of the individual predictors reached statistical significance at the p < 0.05 level: number of IVF attempts (β = −0.118; p = 0.395), age (β = 0.253; p = 0.070), and BMI (β = 0.272; p = 0.052), although age and BMI showed a trend approaching statistical significance. 3.3.

Although some analyses did not demonstrate statistically significant evidence for a clear improvement in the quality of oocytes and embryos, many studies indicate a positive trend in this area.

Research suggests that MI therapy in women with PCOS results in better fertilization rates and a clear trend to a better embryo quality [ 42 ].

We also noted a significant trend of decreasing total FHC and subscale scores with increasing education level. 4.

We observed sixty nominally significant correlations; none survived false discovery rate (FDR) correction (lowest q = 0.08) ( Table S3 ).

A distinct pattern is observed in Kenya, where both caloric availability and protein density show a decreasing trend, accompanied by a strong and statistically significant correlation (τ = 0.800, p = 0.014), suggesting a structurally consistent but negative trajectory ( Figure 3 ).

For zinc intake, a decreasing trend in the odds of DepS was observed with increasing intake, reaching the lowest point near the median intake level, followed by a possible non-linear fluctuation at higher intake levels ( p for non-linearity <0.001).

A decreasing trend was also observed for Bacteroidetes , which play a key role in complex carbohydrate degradation and metabolic balance, indicating a broader weakening of the functional foundation of the gut microbiome [ 73 ].

However, there was a slight trend indicating increased diversification in the PMC94-treated group.

After adjusting WBBMC for weight (WBBMC/kg^1.3), PTH remained a weakly significant predictor of adjusted WBBMC in multivariate regression modeling.

Statistical significance was accepted at p ≤ 0.05 whereas p -values between 0.05 and 0.1 indicated a notable trend due to the small sample size.

The mean value for LCHP could represent a “practically significant” impairment in performance ( i.e. , 1.5–1.8 min) if consistently observed across subjects.

Yet some test measures showed a trend towards improvement from oral β-alanine intake [ 55 ].

Several studies have shown that practicing a good conduct of behavior combined with a nutritious diet and treatment with rasāyanā plants lead to a highly significant improvement in combating various geriatric diseases and augmenting body immunity [ 19 , 20 , 21 , 22 , 23 ]. Āyurvedic texts have described in vivid detail a very wide array of ingredients, including a proper moral code of conduct and personal hygiene, to lead a long, healthy life with enhanced brain functions.

The difference in post treatment regarding MS count between test and control group was not statistically significant, while the difference in follow-up was highly significant [ 16 ].

A meta-analysis [ 15 ] of four genetic association studies [ 19 , 20 , 22 , 25 ], for a total of 354 MDS and 644 control mothers, was performed in 2009 to address the role of the RFC-1 80A>G polymorphism as a maternal risk factor for the birth of a child with DS, and showed a trend toward an association under the dominant model (GG + AG vs .

Although the association of diet with allergic diseases has been studied worldwide, their findings are contradictory and sometimes barely significant.

The Effect of Use of Hormonal Contraceptives on Calcium Homeostasis and Bone Turnover As shown in Table 2 , plasma concentrations of phosphate and osteocalcin were borderline significant lower in users-compared with non-users of HC; whereas no other measured indices differed between groups. 4.

In addition, they also noted an increasing trend with other pro-inflammatory markers like TNF-α and IL-6 with overweight/obesity.

The sensitivity analysis in which one study at a time was omitted generally showed statistically significant or marginally significant results; the pooled ORs ranged from 0.64 (95% CI, 0.46–0.89) to 0.78 (95% CI, 0.57–1.07).

Others have suggested that even if the level of bioavailability of post-absorptive flavonoids is lower than previously reported, localized redox reactions in the gastrointestinal tract may be significant [ 60 ].