Excerpts

Oddly, for both sets of measurements, the difference between wasted and control mice becomes at best weakly significant at 21 days but returns to being highly significant by 22 days.

Moreover, other early, innate cytokines also showed a trend towards increased secretion following treatment with VSL#3-CM, including IL-1β and IL-6, with baseline levels of these cytokines greater than age-matched AKRs.

As regards TGFβ1 serum levels, a negative trend was observed at stages II and III adenocarcinomas, with a significant difference only at stage III ( Figure 3A ).

the most commonly used inflammatory marker, showed a trend quite similar to that of IL-8, with normal serum levels in patients with benign colorectal tumors, and an increase starting from stage II of malignancy, but just below statistical significance ( Figure 2 ).

A decreasing trend of the mean values of (log)apolipoprotein ratio with increasing ethanol intake categories (adjusted for age and BMI) was more pronounced in women than in men (p-value for interaction = 0.04) ( Figure 2 ).

Here, costs are low and revenues are high; for the sampled vessels the fuel consumption is low (9 times less when compared with the trawler) and mainly justified by the journey to and from the fishing area, as fuel used during the hauling of creels is almost insignificant.

0.66–1.16 in Southern European regions), while in men they showed an increasing trend going from North to South (RII Model 4 HR = 0.74, 95% C.I. 0.66–0.84 in Northern, RII Model 4 HR = 0.68, 95% C.I. 0.59–0.78 in Central, and RII Model 4 HR = 0.66, 95% C.I. 0.52–0.82 in Southern European regions) ( Figure 2 ).

0.80–1.07) The association with cardiovascular mortality was highly significant in both men (RII Model4 HR = 0.65, 95% C.I. 0.56–0.76) and women (RII Model4 HR = 0.62, 95% C.I. 0.49–0.78), of comparable magnitude and only partially attenuated by smoking, BMI, and alcohol and fruit and vegetable consumption ( Table 4 ).

Our experimental data show that, in a placebo-controlled setting, nucleoplasty can be used to reduce the initial volume of nucleus pulposus by a statistically highly significant degree.

However, using a cut-point of ASCUS, differences in accuracy were of borderline significance. status released display-pdf yes is-olf no is-manuscript no is-preprint no is-journal-matter no is-scanned no is-retracted no Received 2012 Mar 30; Accepted 2012 May 15; Collection date 2012.

Additionally, −482 genotype showed a trend indicating an association with cholesterolemia under RTV-boosted PI, but with no statistical significance after Bonferroni correction (p = 0.0220).

Thus, although there was a small trend toward increased CD8 T cell infiltration in a peritumoral (‘stalled’) pattern in re-excision samples, this trend did not reach statistical significance.

Highly significant GISTIC peaks not associated with well-established oncogenes or tumor suppressors include 12 p13.33 ( Figure 2E, F ) and 20 q13.12 ( Figure 2G, H ), which had recurrent high-magnitude focal amplifications, as well as 14 q32.31 which, although not highly amplified, had gains of sufficient recurrence and focality as to render a highly significant GISTIC Q-value ( Figure 1B , Table S3 ).

He found a strong trend for preference of north-facing nests at lower latitudes, east-facing nests at mid-latitudes and south-facing nests at upper latitudes and attributed this to the variation in ambient temperatures across this gradient.

This difference is highly significant (see Table 1 , 2 ), indicating that a slight disparity can have a huge influence on the N270.

After correcting for multiple testing, none of these pairs showed nominally significant evidence of interaction in the WTCCC data ( File S1 Supporting Table 2) for the SNP pairs from Analysis 1 (p min = 0.0041; α≈0.05/47≈0.0011), Analysis 2 (p min = 0.0392; α≈0.05/49≈0.001), Analysis 3a (p min = 0.006; α≈0.05/45≈0.001) or Analysis 3b (p min = 0.012; α≈0.05/50≈0.001).

We performed pair-wise SNP interaction testing in three Analyses, first requiring that both potentially interacting SNPs have highly significant effects on CHD risk or CV risk factors (Analysis 1), then relaxing this requirement for one of the SNPs, requiring that it be at least moderately associated with MI (p≤0.001; Analysis 2), and finally requiring that both SNPs have only moderate (p≤0.001) or weak (p≤0.01) marginal association with MI (Analyses 3a and 3b, respectively).

Within this monophyletic group 3 highly significant sub-clades (A, B and C) encompassing 2 or 3 Rumanians and a variable number of Italian isolates (from two to nine each) were identified.

The differences in slopes between HC and patient groups were highly significant for all ROIs (p-values are in Table 2 ).

Interestingly, a procedure-related shortening of CTs (P = 0.087) and a procedure-related increase of MCF (P = 0.055) at maximum suction compared to initial supine rest showed a tendency towards significance ( Table 1 ).

When electrical stimulation was applied to U-46619-treated cPLA 2 α+/+ slices there was a highly significant dilation response when compared to arterioles that were treated with U-46619 but not electrically stimulated ( Figure 5B ).

In lymphocyte cell RNA, from individuals of known rs11573156 genotype, there was no allelic RNA expression difference for exons 5 and 6, but G allele carriers (n = 7) showed a trend to lower exon 1–2 expression compared to CC individuals.

However, the trend for lower serum BDNF levels across quartiles of treadmill test duration approached significance (p-trend = 0.06).

Elevated air humidity significantly reduced height, stem diameter and stem volume increments and transpiration of the trees whereas these effects remained highly significant also after considering the side effects from soil-related confounders within the 2.7 ha study area.

The treatment effect on foliar nutrient concentrations differed between the study years ( Table 4 ) and most of these effects were marginally significant ( q <0.05) through both study years except [K] L , which was substantially ( q <0.01) higher in H plots ( Fig. 4d ).