Barely Significant

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showed a trendp<0.051.0× alpha
Additionally, a few more channels that showed a trend-level difference (uncorrected p<0.05 but not remaining significant after FDR correction) were located approximately in the bilateral frontopolar ([FP]), dorsolateral ([DL]) and ventrolateral ([VL]) regions (uncorrected p<0.01; [FP] ch 36 (d = 0.83; 95%IC 0.19, 1.43), ch47 (d = 0.93; 95%IC 0.26,1.56
marginally significantp = 0.051.0× alphagold
After pleasant picture presentation, a marginally significant decrease of the startle response was observed for val homozygotes dependent on an increase in CTQ scores ( β = −0.51, t = −2.16, p = 0.05), while no associations were observed for val/met ( β = 0.15, t = 0.97, p = 0.34) or met/met genotype carriers ( β = −0.21, t = −1.17, p = 0.25), respectively.
an increasing trendP > 0.051.0× alphagold
did not reach statistical significanceP > 0.051.0× alphaplainly factual
The results of subgroup analysis are shown in S3 Fig in S1 File : in subgroups such as mechanical ventilation, continuous renal replacement therapy, hypertension, diabetes, vasopressors, INR, and fresh frozen plasma, the mortality risk of the rapidly ascending RDW group (Traj1) was significantly higher than that of the stable low-level group (Traj0) ( P < 0.05); while in subgroups such as age, chronic kidney disease, and Hb, although the mortality risk of the Traj1 group showed an increasing trend, the difference in some subgroups did not reach statistical significance ( P > 0.05), which may be related to the limited statistical power of smaller subgroups and residual confounding.