Excerpts

Similar tendency was observed in nominally significant bins (p-value < 0.05).

When a significant trend (P < 0.05) in the air temperature was detected, the magnitude of the slope ( b ) was computed and expressed in °C yr -1 .

The difference in genotypic distribution between POAG males and control male subjects was close to significance threshold (p = 0.050).

parviglumis was highly significant ( X 2 = 113, p-value < 0.05).

When we conditioned on rs2178403, three of the nine variants in the best model for PSMD2 remained nominally significant (p <0.05).

Three additional SNPs from the same intron (rs1071502, rs6497730, and rs1070487) had nominally significant P values for association ( P <0.05), but did not pass the threshold value.

In addition, the top 100 transcripts from the reanalysis of dataset #1 were all nominally significant ( P <0.05) in our analysis of the pooled datasets and 20 transcripts were shared between the top 100 transcripts from dataset #1 and the pooled analyses.

The CMS+fluoxetine group showed a trend of decrease in the plasma level of IL-1β from day 0 to day 120, with significant decrease in IL-1β level on day (60 (206.06±78.41) pg/ml, p <0.05) and day 120 ((141.05±56) pg/ml, p <0.05) as compared to its baseline level on day 0 (344.31±114.33) pg/ml via Wilcoxon signed-rank test.

The significance test in UniFrac [44] reported P-Values (Bonferroni corrected) equal to 1e-02 for every pair of samples of both mother and infant sets, meaning that the results are highly significant (if P-values ≤0.05 are considered to be statistical significant).

The RNA-Seq data were analyzed using a two-way ANOVA with a focus on the two main factors of Exposure (ethanol vs saline) and p53 Genotype (KO vs WT) as well as the interaction between them (Exposure x Genotype).The results indicated that 824 genes showed nominally significant main effects of Genotype (uncorrected P < 0.05), 763 genes had nominally significant main effects of Treatment (uncorrected P-value < 0.05), and 1969 genes had nominally significant interactions of Genotype x Treatment (uncorrected P-value < 0.05).

A decreasing trend was detected for the Na + /K + -ATPase activity and its mRNA expression level in the posterior gills with salinity ( P < 0.05).

All dsRNA fragments ( Fig 4a ) gave highly significant (p < 0,05) down regulation of the target genes giving between 80% (for Lsal IR25a Fragment-1) and nearly 100% (for Lsal IR8a.1) reduction in mRNA levels ( Fig 4b ).

The APdE9 x Bdnf interaction remained marginally significant in females (p = 0.05), but did not reach significance in males (p = 0.08).

To reduce the multiple testing burden, candidate TFs were tested for interaction with a given gene only if their marginal association with the target probe set was nominally significant ( p <0.05).

Unadjusted mean IQ shows a clear trend towards increasing offspring IQ score as parental age increases (p-values<0.05, Table 2 ).

In addition, the LAARP approach had less postoperative complications compared with PSARP, with a marginally significant difference (RR 0.66, 95%CI 0.44–0.99; P = 0.05).

The strength of this effect weakened across subsequent age periods though the pattern across age periods was not significantly different for women (p-value = 0.2 for interaction) and was of borderline significance for men (p-value = 0.05 for interaction).

With Leuppi 2013 included, the mean difference is marginally significant at -0.91 days (95% CI = -1.81–-0.02 days, p = 0.05).

For our replication of previously reported GWAS SNPs (identified mainly in populations of European ancestry) in our multi-ethnic population, we defined nominally significant as ‘p<0.05 and not corrected for multiple testing.’ Given the different recruitment and BP measurement in the Mt.

Only strains from Mallorca and Zaragoza showed a R ST value slightly significant ( P < 0.05).

Such skewing towards overestimating the presence of X4 minority variants for these CRFs was maintained when the FPR cut-off was shifted, although these observations did not reach statistical significance using a Fisher’s exact test (p<0.05).

The all-cause mortality were more highly significant than other combinations ( P <0.05) when the following combinations exist: “elevated blood pressure”, “elevated fasting plasma glucose + low high-density lipoprotein cholesterol”, “elevated blood pressure + elevated triglyceride + elevated fasting plasma glucose”, “elevated fasting plasma glucose + low high-density lipoprotein cholesterol + elevated blood pressure + elevated triglyceride”.

Of the brain regions that loaded positively on the first principal component ( Figure 2B ), on the other hand, ratings of Suffering were significantly correlated with activity in the left anterior thalamus (r = 0.33) and DMPFC (r = 0.38), and showed a positive trend in the right anterior thalamus (r = 0.22, p<0.05); none of these brain regions were positively correlated with Pain, but the DMPFC showed a negative trend with ratings of Pain (r = −0.22, p<0.05).

Of the brain regions that loaded negatively on the first principal component ( Figure 2A ), ratings of Pain positively correlated with brain activity in left insula (pearson's r = 0.44, p<0.002), right insula (r = 0.43) and AMCC (r = 0.47), and showed a positive trend in lSII (r = 0.26, p<0.05) and rSII (r = 0.25, p<0.05); none of these brain regions were positively correlated with Suffering.

BayeScan indicated highly significant probabilities for outlier candidate loci for balancing selection (negative alpha values) for all loci, with the exception of EJ35 ( P > 0.05) ( Table 4 ), but q values were under the 10% threshold for FDR (False Discovery Rate) correction.